SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dyj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AM6_A_HAEA555_1
(CARBONIC ANHYDRASE)		 4dyj BROAD SPECIFICITY
AMINO ACID RACEMASE
(Pseudomonas
putida) 		4 / 7 HIS A 242
HIS A 164
LEU A 239
THR A 240
 None
 0.99A 1am6A-4dyjA:
undetectable		 1am6A-4dyjA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 4dyj BROAD SPECIFICITY
AMINO ACID RACEMASE
(Pseudomonas
putida) 		4 / 8 HIS A 242
HIS A 164
LEU A 239
THR A 240
 None
 1.01A 1azmA-4dyjA:
undetectable		 1azmA-4dyjA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FO4_B_SALB4005_1
(XANTHINE
DEHYDROGENASE)		 4dyj BROAD SPECIFICITY
AMINO ACID RACEMASE
(Pseudomonas
putida) 		4 / 7 SER A 285
THR A 317
VAL A 318
ALA A 314
 None
 0.97A 1fo4B-4dyjA:
undetectable		 1fo4B-4dyjA:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_1
(TRANSTHYRETIN)		 4dyj BROAD SPECIFICITY
AMINO ACID RACEMASE
(Pseudomonas
putida) 		4 / 6 LEU A 257
ALA A 243
LEU A 241
THR A 204
 None
 1.04A 1ictB-4dyjA:
undetectable		 1ictB-4dyjA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PKV_A_RBFA100_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 4dyj BROAD SPECIFICITY
AMINO ACID RACEMASE
(Pseudomonas
putida) 		5 / 11 LEU A 239
THR A 240
ILE A 191
THR A 192
ILE A 163
 None
 1.23A 1pkvA-4dyjA:
5.1
1pkvB-4dyjA:
5.1		 1pkvA-4dyjA:
12.82
1pkvB-4dyjA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_A_ADNA252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4dyj BROAD SPECIFICITY
AMINO ACID RACEMASE
(Pseudomonas
putida) 		5 / 11 GLY A 142
VAL A 177
ILE A 191
HIS A 242
ARG A 261
 None
None
None
None
LLP  A  75 ( 4.0A)
 1.16A 1vhwA-4dyjA:
undetectable
1vhwD-4dyjA:
undetectable		 1vhwA-4dyjA:
20.98
1vhwD-4dyjA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4dyj BROAD SPECIFICITY
AMINO ACID RACEMASE
(Pseudomonas
putida) 		5 / 11 GLY A 142
VAL A 177
ILE A 191
HIS A 242
ARG A 261
 None
None
None
None
LLP  A  75 ( 4.0A)
 1.13A 1vhwC-4dyjA:
undetectable
1vhwE-4dyjA:
undetectable		 1vhwC-4dyjA:
20.98
1vhwE-4dyjA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4dyj BROAD SPECIFICITY
AMINO ACID RACEMASE
(Pseudomonas
putida) 		5 / 11 HIS A 242
ARG A 261
GLY A 142
VAL A 177
ILE A 191
 None
LLP  A  75 ( 4.0A)
None
None
None
 1.14A 1vhwA-4dyjA:
undetectable
1vhwD-4dyjA:
undetectable		 1vhwA-4dyjA:
20.98
1vhwD-4dyjA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_E_ADNE252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4dyj BROAD SPECIFICITY
AMINO ACID RACEMASE
(Pseudomonas
putida) 		5 / 11 HIS A 242
ARG A 261
GLY A 142
VAL A 177
ILE A 191
 None
LLP  A  75 ( 4.0A)
None
None
None
 1.17A 1vhwC-4dyjA:
undetectable
1vhwE-4dyjA:
undetectable		 1vhwC-4dyjA:
20.98
1vhwE-4dyjA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A164_1
(BETA-LACTOGLOBULIN)		 4dyj BROAD SPECIFICITY
AMINO ACID RACEMASE
(Pseudomonas
putida) 		4 / 5 ASP A 394
LEU A 395
MET A 384
ARG A 325
 None
 1.46A 2gj5A-4dyjA:
undetectable		 2gj5A-4dyjA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_A_ANWA99_0
(PROTEIN S100-A13)		 4dyj BROAD SPECIFICITY
AMINO ACID RACEMASE
(Pseudomonas
putida) 		4 / 7 MET A 353
THR A 304
PHE A 305
THR A 298
 None
 1.04A 2kotA-4dyjA:
undetectable		 2kotA-4dyjA:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_1
(CYTOCHROME P450 2C8)		 4dyj BROAD SPECIFICITY
AMINO ACID RACEMASE
(Pseudomonas
putida) 		5 / 12 ASN A 245
ASN A 175
THR A 270
ALA A  72
VAL A 119
 LLP  A  75 ( 4.2A)
None
None
None
None
 1.28A 2nniA-4dyjA:
undetectable		 2nniA-4dyjA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 4dyj BROAD SPECIFICITY
AMINO ACID RACEMASE
(Pseudomonas
putida) 		4 / 5 SER A 246
GLY A 263
ASP A 409
ASP A 269
 LLP  A  75 ( 2.6A)
LLP  A  75 ( 3.5A)
SO4  A 503 (-4.6A)
None
 1.04A 2oxtB-4dyjA:
undetectable		 2oxtB-4dyjA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ROX_B_T44B128_1
(TRANSTHYRETIN)		 4dyj BROAD SPECIFICITY
AMINO ACID RACEMASE
(Pseudomonas
putida) 		4 / 6 LEU A 257
ALA A 243
LEU A 241
THR A 204
 None
 1.03A 2roxB-4dyjA:
undetectable		 2roxB-4dyjA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_A_SALA1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4dyj BROAD SPECIFICITY
AMINO ACID RACEMASE
(Pseudomonas
putida) 		4 / 8 SER A 285
THR A 317
VAL A 318
LEU A 352
 None
 0.96A 3ax7A-4dyjA:
undetectable		 3ax7A-4dyjA:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_B_SALB1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4dyj BROAD SPECIFICITY
AMINO ACID RACEMASE
(Pseudomonas
putida) 		5 / 9 SER A 285
THR A 317
VAL A 318
LEU A 352
ALA A 314
 None
 1.01A 3ax7B-4dyjA:
undetectable		 3ax7B-4dyjA:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_B_SAMB600_0
(PCZA361.24)		 4dyj BROAD SPECIFICITY
AMINO ACID RACEMASE
(Pseudomonas
putida) 		5 / 12 ALA A 188
GLY A 184
LEU A 189
SER A 143
GLY A 142
 None
 1.10A 3g2oB-4dyjA:
undetectable		 3g2oB-4dyjA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_C_9PLC1_1
(CYTOCHROME P450 2A13)		 4dyj BROAD SPECIFICITY
AMINO ACID RACEMASE
(Pseudomonas
putida) 		4 / 7 PHE A 267
ALA A 265
THR A 262
LEU A  70
 None
 0.82A 3t3sC-4dyjA:
undetectable		 3t3sC-4dyjA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 4dyj BROAD SPECIFICITY
AMINO ACID RACEMASE
(Pseudomonas
putida) 		4 / 8 HIS A 242
HIS A 164
LEU A 239
THR A 240
 None
 1.05A 3w6hA-4dyjA:
undetectable		 3w6hA-4dyjA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_A_UEGA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 4dyj BROAD SPECIFICITY
AMINO ACID RACEMASE
(Pseudomonas
putida) 		5 / 11 GLY A 400
ASP A  77
ALA A  78
GLY A  80
VAL A  48
 None
 1.02A 4c5lA-4dyjA:
undetectable		 4c5lA-4dyjA:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_B_PXLB300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 4dyj BROAD SPECIFICITY
AMINO ACID RACEMASE
(Pseudomonas
putida) 		5 / 9 GLY A 400
ASP A  77
ALA A  78
GLY A  80
VAL A  48
 None
 1.02A 4c5lB-4dyjA:
2.3		 4c5lB-4dyjA:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_C_UEGC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 4dyj BROAD SPECIFICITY
AMINO ACID RACEMASE
(Pseudomonas
putida) 		5 / 10 GLY A 400
ASP A  77
ALA A  78
GLY A  80
VAL A  48
 None
 1.00A 4c5lC-4dyjA:
undetectable		 4c5lC-4dyjA:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 4dyj BROAD SPECIFICITY
AMINO ACID RACEMASE
(Pseudomonas
putida) 		5 / 10 GLY A 400
ASP A  77
ALA A  78
GLY A  80
VAL A  48
 None
 1.00A 4c5lD-4dyjA:
undetectable		 4c5lD-4dyjA:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_B_PXLB300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 4dyj BROAD SPECIFICITY
AMINO ACID RACEMASE
(Pseudomonas
putida) 		5 / 10 GLY A 400
ASP A  77
ALA A  78
GLY A  80
VAL A  48
 None
 1.00A 4c5nB-4dyjA:
2.1		 4c5nB-4dyjA:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 4dyj BROAD SPECIFICITY
AMINO ACID RACEMASE
(Pseudomonas
putida) 		5 / 10 GLY A 400
ASP A  77
ALA A  78
GLY A  80
VAL A  48
 None
 1.09A 4c5nD-4dyjA:
2.5		 4c5nD-4dyjA:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I89_A_1FLA201_1
(TRANSTHYRETIN)		 4dyj BROAD SPECIFICITY
AMINO ACID RACEMASE
(Pseudomonas
putida) 		4 / 6 LEU A 257
ALA A 243
LEU A 241
THR A 204
 None
 0.98A 4i89A-4dyjA:
undetectable		 4i89A-4dyjA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_B_FUAB1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 4dyj BROAD SPECIFICITY
AMINO ACID RACEMASE
(Pseudomonas
putida) 		4 / 5 ILE A 341
LEU A 307
HIS A 291
VAL A 290
 None
 1.11A 5jmnB-4dyjA:
undetectable		 5jmnB-4dyjA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_A_6J3A201_0
(TRANSTHYRETIN)		 4dyj BROAD SPECIFICITY
AMINO ACID RACEMASE
(Pseudomonas
putida) 		4 / 6 LEU A 257
ALA A 243
LEU A 241
THR A 204
 None
 0.98A 5l4iA-4dyjA:
undetectable		 5l4iA-4dyjA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_C_DAHC60_1
(PUTATIVE CYTOCHROME
C)		 4dyj BROAD SPECIFICITY
AMINO ACID RACEMASE
(Pseudomonas
putida) 		4 / 6 HIS A 242
ASN A 175
VAL A 141
LEU A 199
 None
 1.34A 5xdhA-4dyjA:
undetectable
5xdhC-4dyjA:
undetectable		 5xdhA-4dyjA:
10.73
5xdhC-4dyjA:
10.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_A_HFGA801_0
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 4dyj BROAD SPECIFICITY
AMINO ACID RACEMASE
(Pseudomonas
putida) 		5 / 12 PHE A 328
VAL A 334
THR A 397
SER A 402
GLY A 400
 None
 1.25A 5xioA-4dyjA:
undetectable		 5xioA-4dyjA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 4dyj BROAD SPECIFICITY
AMINO ACID RACEMASE
(Pseudomonas
putida) 		4 / 7 ILE A 341
VAL A 343
ILE A 316
THR A 351
 None
None
None
GOL  A 508 (-4.6A)
 1.00A 6cduF-4dyjA:
undetectable
6cduG-4dyjA:
undetectable		 6cduF-4dyjA:
21.18
6cduG-4dyjA:
21.18