SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dyu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_A_ACTA294_0
(GLYCINE
N-METHYLTRANSFERASE)		 4dyu DNA PROTECTION
DURING STARVATION
PROTEIN
(Yersinia
pestis) 		4 / 5 ILE A 127
LEU A 159
ALA A 122
GLU A 123
 None
 1.18A 1xvaA-4dyuA:
undetectable
1xvaB-4dyuA:
undetectable		 1xvaA-4dyuA:
22.87
1xvaB-4dyuA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_B_URFB400_1
(URIDINE
PHOSPHORYLASE 1)		 4dyu DNA PROTECTION
DURING STARVATION
PROTEIN
(Yersinia
pestis) 		4 / 8 THR A  47
LEU A 121
LEU A 118
ILE A 162
 None
 0.90A 3nbqB-4dyuA:
undetectable		 3nbqB-4dyuA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_D_NCAD302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 4dyu DNA PROTECTION
DURING STARVATION
PROTEIN
(Yersinia
pestis) 		4 / 7 LEU A  73
ASP A 154
ALA A 151
TYR A 125
 None
 0.83A 3rodD-4dyuA:
undetectable		 3rodD-4dyuA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4dyu DNA PROTECTION
DURING STARVATION
PROTEIN
(Yersinia
pestis) 		4 / 8 THR A  17
GLY A  88
GLY A  89
VAL A  85
 None
 0.79A 4qvvK-4dyuA:
undetectable
4qvvL-4dyuA:
undetectable		 4qvvK-4dyuA:
20.96
4qvvL-4dyuA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4dyu DNA PROTECTION
DURING STARVATION
PROTEIN
(Yersinia
pestis) 		4 / 8 THR A  17
GLY A  88
GLY A  89
VAL A  85
 None
 0.79A 4qvvY-4dyuA:
undetectable
4qvvZ-4dyuA:
undetectable		 4qvvY-4dyuA:
20.96
4qvvZ-4dyuA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_A_ADNA303_1
(5'/3'-NUCLEOTIDASE
SURE)		 4dyu DNA PROTECTION
DURING STARVATION
PROTEIN
(Yersinia
pestis) 		5 / 10 ASN A 130
ALA A 120
ILE A  46
LEU A  43
TYR A 107
 None
 1.16A 4xj7A-4dyuA:
undetectable
4xj7B-4dyuA:
undetectable		 4xj7A-4dyuA:
20.70
4xj7B-4dyuA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_1
(THYROXINE-BINDING
GLOBULIN)		 4dyu DNA PROTECTION
DURING STARVATION
PROTEIN
(Yersinia
pestis) 		5 / 10 LEU A 104
LEU A  43
SER A 152
LEU A 155
LEU A 121
 None
 1.17A 4yiaA-4dyuA:
undetectable		 4yiaA-4dyuA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFP_A_8W5A804_2
(GLUCOCORTICOID
RECEPTOR)		 4dyu DNA PROTECTION
DURING STARVATION
PROTEIN
(Yersinia
pestis) 		4 / 4 LEU A  77
MET A 147
ILE A  38
LEU A  33
 None
 1.42A 5nfpA-4dyuA:
undetectable		 5nfpA-4dyuA:
20.50