SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dyv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_0
(HEMK PROTEIN)		 4dyv SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Xanthobacter
autotrophicus) 		5 / 12 ILE A  32
GLY A  59
VAL A  89
GLU A 144
ASN A 109
 None
 1.18A 1sg9A-4dyvA:
7.1		 1sg9A-4dyvA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC2_0
(N8-ACTINOMYCIN D)		 4dyv SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Xanthobacter
autotrophicus) 		3 / 3 THR A 178
PRO A 176
THR A 180
 CL  A 301 ( 4.0A)
None
None
 0.80A 209dC-4dyvA:
undetectable		 209dC-4dyvA:
3.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1476_0
(MJ0495-LIKE PROTEIN)		 4dyv SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Xanthobacter
autotrophicus) 		4 / 5 ILE A 159
HIS A 198
MET A 149
ARG A 147
 None
 1.34A 4ac9B-4dyvA:
7.5
4ac9C-4dyvA:
7.3		 4ac9B-4dyvA:
20.48
4ac9C-4dyvA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1476_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4dyv SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Xanthobacter
autotrophicus) 		4 / 4 ILE A 159
HIS A 198
MET A 149
ARG A 147
 None
 1.29A 4acbB-4dyvA:
6.5
4acbC-4dyvA:
4.2		 4acbB-4dyvA:
20.48
4acbC-4dyvA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DPD_B_SAMB601_0
(PROTEIN LYSINE
METHYLTRANSFERASE 1)		 4dyv SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Xanthobacter
autotrophicus) 		5 / 12 GLY A 163
SER A 166
ILE A 205
VAL A  40
VAL A 240
 None
 1.05A 5dpdB-4dyvA:
6.5		 5dpdB-4dyvA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4dyv SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Xanthobacter
autotrophicus) 		4 / 7 ALA A  95
THR A  94
VAL A 148
GLU A 144
 None
 1.21A 5ecnA-4dyvA:
undetectable		 5ecnA-4dyvA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 4dyv SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Xanthobacter
autotrophicus) 		5 / 12 GLY A  35
GLY A  37
ASP A  82
VAL A  83
THR A  84
 None
 0.80A 5kpcB-4dyvA:
5.5		 5kpcB-4dyvA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NQA_K_SAMK500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 4dyv SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Xanthobacter
autotrophicus) 		5 / 10 THR A 188
ASP A 206
GLY A 163
ASN A 161
PHE A 107
 None
 1.45A 6nqaK-4dyvA:
undetectable		 6nqaK-4dyvA:
22.35