SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dz3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		8 / 9 TYR A  33
ASP A  44
PHE A  53
VAL A  62
ILE A  63
TRP A  66
TYR A  89
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
FK5  A 201 (-4.8A)
 0.32A 1bkfA-4dz3A:
18.9		 1bkfA-4dz3A:
53.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1C9H_A_RAPA108_1
(FKBP12.6)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		8 / 12 TYR A  33
ASP A  44
PHE A  53
VAL A  62
ILE A  63
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.43A 1c9hA-4dz3A:
18.3		 1c9hA-4dz3A:
48.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FAP_A_RAPA108_1
(FK506-BINDING
PROTEIN)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		9 / 12 TYR A  33
ASP A  44
PHE A  53
VAL A  62
ILE A  63
TRP A  66
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.37A 1fapA-4dz3A:
19.2		 1fapA-4dz3A:
53.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKB_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		8 / 12 TYR A  33
ASP A  44
PHE A  53
VAL A  62
ILE A  63
TRP A  66
TYR A  89
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
FK5  A 201 (-4.8A)
 0.30A 1fkbA-4dz3A:
19.0		 1fkbA-4dz3A:
53.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		10 / 11 TYR A  33
ASP A  44
ARG A  49
PHE A  53
VAL A  62
ILE A  63
TRP A  66
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 ( 3.7A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.40A 1fkfA-4dz3A:
18.8		 1fkfA-4dz3A:
53.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKJ_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		10 / 11 TYR A  33
ASP A  44
ARG A  49
PHE A  53
VAL A  62
ILE A  63
TRP A  66
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 ( 3.7A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.42A 1fkjA-4dz3A:
18.8		 1fkjA-4dz3A:
53.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKL_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		9 / 12 TYR A  33
ASP A  44
PHE A  53
VAL A  62
ILE A  63
TRP A  66
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.34A 1fklA-4dz3A:
18.9		 1fklA-4dz3A:
54.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_0
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		5 / 12 GLY A  77
GLY A  69
ALA A  23
VAL A 113
LEU A  57
 None
 1.12A 1jg4A-4dz3A:
undetectable		 1jg4A-4dz3A:
22.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PBK_A_RAPA225_1
(FKBP25)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		5 / 12 TYR A  33
ASP A  44
GLY A  59
TRP A  66
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
None
FK5  A 201 (-3.4A)
FK5  A 201 (-4.8A)
 0.79A 1pbkA-4dz3A:
18.1		 1pbkA-4dz3A:
41.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PBK_A_RAPA225_1
(FKBP25)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		9 / 12 TYR A  33
ASP A  44
GLY A  60
VAL A  62
ILE A  63
TRP A  66
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
None
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.37A 1pbkA-4dz3A:
18.1		 1pbkA-4dz3A:
41.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PBK_A_RAPA225_1
(FKBP25)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		7 / 12 TYR A  33
GLY A  60
VAL A  62
TRP A  66
ALA A  94
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
None
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.4A)
FK5  A 201 ( 4.6A)
None
FK5  A 201 (-4.8A)
 1.03A 1pbkA-4dz3A:
18.1		 1pbkA-4dz3A:
41.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Q6I_A_FK5A301_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		8 / 9 TYR A  33
ASP A  44
VAL A  62
ILE A  63
TRP A  66
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.37A 1q6iA-4dz3A:
18.5		 1q6iA-4dz3A:
30.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Q6I_B_FK5B401_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		9 / 10 TYR A  33
ASP A  44
ARG A  49
VAL A  62
ILE A  63
TRP A  66
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 ( 3.7A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.56A 1q6iB-4dz3A:
18.3		 1q6iB-4dz3A:
30.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TCO_C_FK5C509_2
(FK506-BINDING
PROTEIN)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		10 / 11 TYR A  33
ASP A  44
ARG A  49
PHE A  53
VAL A  62
ILE A  63
TRP A  66
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 ( 3.7A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.46A 1tcoC-4dz3A:
18.7		 1tcoC-4dz3A:
53.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YAT_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		10 / 11 TYR A  33
ASP A  44
ARG A  49
PHE A  53
VAL A  62
ILE A  63
TRP A  66
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 ( 3.7A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.32A 1yatA-4dz3A:
21.2		 1yatA-4dz3A:
51.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG3_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		8 / 11 TYR A  33
ASP A  44
PHE A  53
VAL A  62
ILE A  63
TRP A  66
TYR A  89
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
FK5  A 201 (-4.8A)
 0.36A 2dg3A-4dz3A:
18.8		 2dg3A-4dz3A:
53.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG4_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		7 / 11 TYR A  33
ASP A  44
PHE A  53
VAL A  62
ILE A  63
TYR A  89
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-4.7A)
FK5  A 201 (-4.8A)
 0.36A 2dg4A-4dz3A:
18.3		 2dg4A-4dz3A:
53.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG9_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		7 / 11 TYR A  33
ASP A  44
PHE A  53
VAL A  62
ILE A  63
TYR A  89
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-4.7A)
FK5  A 201 (-4.8A)
 0.38A 2dg9A-4dz3A:
18.6		 2dg9A-4dz3A:
53.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FKE_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		10 / 11 TYR A  33
ASP A  44
ARG A  49
PHE A  53
VAL A  62
ILE A  63
TRP A  66
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 ( 3.7A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.40A 2fkeA-4dz3A:
18.9		 2fkeA-4dz3A:
53.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_B_SALB503_1
(SALICYLATE
SYNTHETASE, IRP9)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		5 / 11 GLY A   9
THR A   6
THR A  82
GLY A  65
GLU A  68
 None
 1.05A 2fn1B-4dz3A:
undetectable		 2fn1B-4dz3A:
14.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VCD_A_RAPA138_1
(OUTER MEMBRANE
PROTEIN MIP)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		6 / 11 TYR A  33
PHE A  43
ASP A  44
VAL A  62
ILE A  63
TRP A  66
 FK5  A 201 ( 3.9A)
FK5  A 201 (-4.8A)
FK5  A 201 (-3.5A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
 0.82A 2vcdA-4dz3A:
15.2		 2vcdA-4dz3A:
34.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VCD_A_RAPA138_1
(OUTER MEMBRANE
PROTEIN MIP)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		6 / 11 TYR A  33
PHE A  43
VAL A  62
ILE A  63
TRP A  66
TYR A  89
 FK5  A 201 ( 3.9A)
FK5  A 201 (-4.8A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
 0.90A 2vcdA-4dz3A:
15.2		 2vcdA-4dz3A:
34.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VN1_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		10 / 11 TYR A  33
PHE A  43
ASP A  44
ARG A  49
PHE A  53
VAL A  62
TRP A  66
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-4.8A)
FK5  A 201 (-3.5A)
FK5  A 201 ( 3.7A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.42A 2vn1A-4dz3A:
20.1		 2vn1A-4dz3A:
40.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VN1_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		4 / 6 LEU A  15
SER A  45
ASP A  48
GLU A 107
 None
 0.79A 2vn1B-4dz3A:
20.1		 2vn1B-4dz3A:
40.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VN1_B_FK5B501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		9 / 10 TYR A  33
ASP A  44
ARG A  49
PHE A  53
VAL A  62
ILE A  63
TRP A  66
TYR A  89
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 ( 3.7A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
FK5  A 201 (-4.8A)
 0.50A 2vn1B-4dz3A:
20.1		 2vn1B-4dz3A:
40.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IHZ_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		10 / 10 TYR A  33
ASP A  44
ARG A  49
PHE A  53
VAL A  62
ILE A  63
TRP A  66
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 ( 3.7A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.42A 3ihzA-4dz3A:
20.2		 3ihzA-4dz3A:
40.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IHZ_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		6 / 8 TYR A  33
PHE A  53
TRP A  66
TYR A  89
GLY A  95
ILE A  98
 FK5  A 201 ( 3.9A)
FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
None
 0.61A 3ihzB-4dz3A:
20.4		 3ihzB-4dz3A:
40.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KZ7_A_RAPA225_1
(FK506-BINDING
PROTEIN 3)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		8 / 10 TYR A  33
ASP A  44
VAL A  62
ILE A  63
TRP A  66
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.25A 3kz7A-4dz3A:
18.2		 3kz7A-4dz3A:
40.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3O5R_A_FK5A1001_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		10 / 11 TYR A  33
ASP A  44
ARG A  49
PHE A  53
VAL A  62
ILE A  63
TRP A  66
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 ( 3.7A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.50A 3o5rA-4dz3A:
19.3		 3o5rA-4dz3A:
46.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UF8_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		10 / 10 TYR A  33
ASP A  44
ARG A  49
PHE A  53
VAL A  62
ILE A  63
TRP A  66
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 ( 3.7A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.36A 3uf8A-4dz3A:
24.5		 3uf8A-4dz3A:
98.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UQA_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		10 / 10 TYR A  33
ASP A  44
ARG A  49
PHE A  53
VAL A  62
ILE A  63
TRP A  66
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 ( 3.7A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.32A 3uqaA-4dz3A:
22.7		 3uqaA-4dz3A:
98.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UQB_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		8 / 8 TYR A  33
PHE A  53
VAL A  62
ILE A  63
TRP A  66
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.29A 3uqbA-4dz3A:
18.0		 3uqbA-4dz3A:
98.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VAW_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN
SMT3,PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		10 / 11 TYR A  33
ASP A  44
ARG A  49
PHE A  53
VAL A  62
ILE A  63
TRP A  66
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 ( 3.7A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.24A 3vawA-4dz3A:
22.8		 3vawA-4dz3A:
98.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRH_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		9 / 12 TYR A  33
ASP A  44
PHE A  53
VAL A  62
ILE A  63
TRP A  66
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.48A 4drhA-4dz3A:
18.0		 4drhA-4dz3A:
41.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRH_D_RAPD201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		9 / 12 TYR A  33
ASP A  44
PHE A  53
VAL A  62
ILE A  63
TRP A  66
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.46A 4drhD-4dz3A:
17.9		 4drhD-4dz3A:
41.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRI_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		8 / 11 TYR A  33
ASP A  44
ARG A  49
ILE A  63
TRP A  66
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 ( 3.7A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.77A 4driA-4dz3A:
19.8		 4driA-4dz3A:
41.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRI_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		9 / 11 TYR A  33
ASP A  44
PHE A  53
VAL A  62
ILE A  63
TRP A  66
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.34A 4driA-4dz3A:
19.8		 4driA-4dz3A:
41.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRJ_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		9 / 11 TYR A  33
ASP A  44
PHE A  53
VAL A  62
ILE A  63
TRP A  66
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.32A 4drjA-4dz3A:
19.8		 4drjA-4dz3A:
46.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ2_A_FK5A200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		10 / 11 TYR A  33
ASP A  44
ARG A  49
PHE A  53
VAL A  62
ILE A  63
TRP A  66
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 ( 3.7A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.48A 4dz2A-4dz3A:
25.0
4dz2B-4dz3A:
25.0		 4dz2A-4dz3A:
98.23
4dz2B-4dz3A:
98.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ2_B_FK5B200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		10 / 11 TYR A  33
ASP A  44
ARG A  49
PHE A  53
VAL A  62
ILE A  63
TRP A  66
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 ( 3.7A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.51A 4dz2A-4dz3A:
25.0
4dz2B-4dz3A:
25.0		 4dz2A-4dz3A:
98.23
4dz2B-4dz3A:
98.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAX_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		9 / 10 TYR A  33
ASP A  44
PHE A  53
VAL A  62
ILE A  63
TRP A  66
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.30A 4laxA-4dz3A:
19.9		 4laxA-4dz3A:
29.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NNR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		9 / 12 TYR A  33
ASP A  44
PHE A  53
VAL A  62
ILE A  63
TRP A  66
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.19A 4nnrA-4dz3A:
16.6
4nnrB-4dz3A:
16.7		 4nnrA-4dz3A:
45.52
4nnrB-4dz3A:
45.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NNR_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		9 / 10 TYR A  33
ASP A  44
PHE A  53
VAL A  62
ILE A  63
TRP A  66
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.22A 4nnrB-4dz3A:
16.7		 4nnrB-4dz3A:
45.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_A_FK5A205_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		5 / 10 TYR A  33
ASP A  44
ILE A  63
TYR A  89
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 (-3.8A)
FK5  A 201 (-4.7A)
FK5  A 201 (-4.8A)
 0.35A 4odoA-4dz3A:
11.6		 4odoA-4dz3A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		5 / 10 TYR A  33
ASP A  44
ILE A  63
TYR A  89
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 (-3.8A)
FK5  A 201 (-4.7A)
FK5  A 201 (-4.8A)
 0.34A 4odoB-4dz3A:
11.4		 4odoB-4dz3A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_C_FK5C204_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		5 / 10 TYR A  33
ASP A  44
ILE A  63
TYR A  89
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 (-3.8A)
FK5  A 201 (-4.7A)
FK5  A 201 (-4.8A)
 0.35A 4odoC-4dz3A:
11.3		 4odoC-4dz3A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		6 / 12 TYR A  33
ASP A  44
ILE A  63
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 (-3.8A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.41A 4odrA-4dz3A:
13.5
4odrB-4dz3A:
13.3		 4odrA-4dz3A:
25.71
4odrB-4dz3A:
25.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		5 / 11 TYR A  33
ASP A  44
ILE A  63
TYR A  89
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 (-3.8A)
FK5  A 201 (-4.7A)
FK5  A 201 (-4.8A)
 0.33A 4odrA-4dz3A:
13.5
4odrB-4dz3A:
13.3		 4odrA-4dz3A:
25.71
4odrB-4dz3A:
25.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QT2_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		9 / 10 TYR A  33
ASP A  44
PHE A  53
VAL A  62
ILE A  63
TRP A  66
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.32A 4qt2A-4dz3A:
20.3		 4qt2A-4dz3A:
38.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QT3_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		9 / 10 TYR A  33
ASP A  44
PHE A  53
VAL A  62
ILE A  63
TRP A  66
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.41A 4qt3A-4dz3A:
18.8		 4qt3A-4dz3A:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5B8I_C_FK5C201_3
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		10 / 12 TYR A  33
ASP A  44
ARG A  49
PHE A  53
VAL A  62
ILE A  63
TRP A  66
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 ( 3.7A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.52A 5b8iC-4dz3A:
18.0		 5b8iC-4dz3A:
41.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D75_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		8 / 11 TYR A  33
ASP A  44
VAL A  62
ILE A  63
TRP A  66
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.30A 5d75A-4dz3A:
18.1		 5d75A-4dz3A:
41.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GPG_A_RAPA301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		8 / 11 TYR A  33
ASP A  44
VAL A  62
ILE A  63
TRP A  66
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.21A 5gpgA-4dz3A:
19.1		 5gpgA-4dz3A:
42.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HKG_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1B)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		8 / 12 TYR A  33
ASP A  44
PHE A  53
VAL A  62
ILE A  63
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.40A 5hkgA-4dz3A:
18.6		 5hkgA-4dz3A:
48.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HUA_A_FK5A201_1
(FK506-BINDING
PROTEIN 1)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		9 / 11 TYR A  33
ASP A  44
ARG A  49
PHE A  53
VAL A  62
ILE A  63
TRP A  66
TYR A  89
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 ( 3.7A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
FK5  A 201 (-4.8A)
 0.31A 5huaA-4dz3A:
21.3		 5huaA-4dz3A:
51.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_A_FK5A201_1
(FK506-BINDING
PROTEIN 1)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		9 / 11 TYR A  33
ASP A  44
ARG A  49
PHE A  53
VAL A  62
ILE A  63
TRP A  66
TYR A  89
ILE A  98
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 ( 3.7A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
 0.72A 5hw8A-4dz3A:
17.8
5hw8D-4dz3A:
17.9		 5hw8A-4dz3A:
47.90
5hw8D-4dz3A:
47.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_B_FK5B201_1
(FK506-BINDING
PROTEIN 1)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		9 / 11 TYR A  33
ASP A  44
ARG A  49
PHE A  53
VAL A  62
TRP A  66
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 ( 3.7A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.54A 5hw8B-4dz3A:
18.1		 5hw8B-4dz3A:
47.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_C_FK5C201_1
(FK506-BINDING
PROTEIN 1)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		9 / 10 TYR A  33
ASP A  44
ARG A  49
VAL A  62
ILE A  63
TRP A  66
TYR A  89
LEU A 104
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 ( 3.7A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.71A 5hw8C-4dz3A:
17.8
5hw8H-4dz3A:
15.2		 5hw8C-4dz3A:
47.90
5hw8H-4dz3A:
47.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_D_FK5D201_1
(FK506-BINDING
PROTEIN 1)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		10 / 11 TYR A  33
ASP A  44
ARG A  49
PHE A  53
VAL A  62
ILE A  63
TRP A  66
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 ( 3.7A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.56A 5hw8D-4dz3A:
17.9		 5hw8D-4dz3A:
47.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_E_FK5E201_1
(FK506-BINDING
PROTEIN 1)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		9 / 11 TYR A  33
ASP A  44
ARG A  49
PHE A  53
VAL A  62
ILE A  63
TRP A  66
TYR A  89
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 ( 3.7A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
FK5  A 201 (-4.8A)
 0.51A 5hw8E-4dz3A:
17.8		 5hw8E-4dz3A:
47.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_F_FK5F201_1
(FK506-BINDING
PROTEIN 1)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		8 / 12 TYR A  33
ASP A  44
PHE A  53
VAL A  62
ILE A  63
TRP A  66
TYR A  89
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
FK5  A 201 (-4.8A)
 0.42A 5hw8B-4dz3A:
18.1
5hw8F-4dz3A:
15.1
5hw8G-4dz3A:
17.5		 5hw8B-4dz3A:
47.90
5hw8F-4dz3A:
47.90
5hw8G-4dz3A:
47.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_G_FK5G201_2
(FK506-BINDING
PROTEIN 1)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		9 / 11 TYR A  33
ASP A  44
PHE A  53
VAL A  62
ILE A  63
TRP A  66
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.47A 5hw8G-4dz3A:
17.5		 5hw8G-4dz3A:
47.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_H_FK5H201_1
(FK506-BINDING
PROTEIN 1)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		7 / 8 TYR A  33
ASP A  44
PHE A  53
VAL A  62
ILE A  63
TRP A  66
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.8A)
 0.58A 5hw8H-4dz3A:
15.2		 5hw8H-4dz3A:
47.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HWC_A_FK5A201_1
(FK506-BINDING
PROTEIN 1A)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		10 / 11 TYR A  33
ASP A  44
ARG A  49
PHE A  53
VAL A  62
ILE A  63
TRP A  66
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 ( 3.7A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.30A 5hwcA-4dz3A:
19.5		 5hwcA-4dz3A:
55.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_A_FK5A201_0
(PEPTIDYLPROLYL
ISOMERASE)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		10 / 12 TYR A  33
ASP A  44
ARG A  49
PHE A  53
VAL A  62
ILE A  63
TRP A  66
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 ( 3.7A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.50A 6mkeA-4dz3A:
20.3
6mkeD-4dz3A:
20.4		 6mkeA-4dz3A:
53.52
6mkeD-4dz3A:
53.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_B_FK5B201_0
(PEPTIDYLPROLYL
ISOMERASE)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		10 / 12 TYR A  33
ASP A  44
ARG A  49
PHE A  53
VAL A  62
ILE A  63
TRP A  66
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 ( 3.7A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.48A 6mkeB-4dz3A:
20.3
6mkeC-4dz3A:
20.3		 6mkeB-4dz3A:
53.52
6mkeC-4dz3A:
53.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_C_FK5C201_1
(PEPTIDYLPROLYL
ISOMERASE)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		10 / 10 TYR A  33
ASP A  44
ARG A  49
PHE A  53
VAL A  62
ILE A  63
TRP A  66
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 ( 3.7A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.39A 6mkeC-4dz3A:
20.3		 6mkeC-4dz3A:
53.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_D_FK5D201_1
(PEPTIDYLPROLYL
ISOMERASE)		 4dz3 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Burkholderia
pseudomallei) 		10 / 10 TYR A  33
ASP A  44
ARG A  49
PHE A  53
VAL A  62
ILE A  63
TRP A  66
TYR A  89
ILE A  98
PHE A 106
 FK5  A 201 ( 3.9A)
FK5  A 201 (-3.5A)
FK5  A 201 ( 3.7A)
FK5  A 201 (-4.1A)
FK5  A 201 ( 3.6A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.7A)
None
FK5  A 201 (-4.8A)
 0.36A 6mkeD-4dz3A:
20.4		 6mkeD-4dz3A:
53.52