SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dza'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB8_0
(ACTINOMYCIN D)		 4dza LYSINE RACEMASE
(Proteus
mirabilis) 		3 / 3 THR A 250
THR A 248
PRO A 252
 None
 0.78A 1a7yB-4dzaA:
undetectable		 1a7yB-4dzaA:
8.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMA_A_NCAA700_0
(EXOTOXIN A)		 4dza LYSINE RACEMASE
(Proteus
mirabilis) 		4 / 7 HIS A  80
GLY A  79
ALA A  77
TYR A  78
 None
None
None
LLP  A  74 ( 4.4A)
 0.87A 1dmaA-4dzaA:
undetectable		 1dmaA-4dzaA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4002_1
(SERUM ALBUMIN)		 4dza LYSINE RACEMASE
(Proteus
mirabilis) 		4 / 6 LEU A 233
VAL A 198
SER A 191
GLN A 192
 None
 1.11A 1e7aB-4dzaA:
undetectable		 1e7aB-4dzaA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE2_0
(ACTINOMYCIN D)		 4dza LYSINE RACEMASE
(Proteus
mirabilis) 		3 / 3 THR A 248
PRO A 252
THR A 250
 None
 0.80A 1i3wE-4dzaA:
undetectable		 1i3wE-4dzaA:
8.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)		 4dza LYSINE RACEMASE
(Proteus
mirabilis) 		3 / 3 THR A 248
PRO A 252
THR A 250
 None
 0.83A 1i3wG-4dzaA:
undetectable		 1i3wG-4dzaA:
8.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_B_NOVB444_2
(DNA GYRASE SUBUNIT B)		 4dza LYSINE RACEMASE
(Proteus
mirabilis) 		3 / 3 ASP A 320
PHE A 368
VAL A 350
 None
 0.75A 1kijB-4dzaA:
undetectable		 1kijB-4dzaA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OVF_B_DVAB2_0
(ACTINOMYCIN D)		 4dza LYSINE RACEMASE
(Proteus
mirabilis) 		3 / 3 THR A 248
PRO A 252
THR A 250
 None
 0.82A 1ovfB-4dzaA:
undetectable		 1ovfB-4dzaA:
8.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_B_DVAB8_0
(ACTINOMYCIN X2)		 4dza LYSINE RACEMASE
(Proteus
mirabilis) 		3 / 3 THR A 250
THR A 248
PRO A 252
 None
 0.73A 1qfiB-4dzaA:
undetectable		 1qfiB-4dzaA:
8.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA502_1
(YKOF)		 4dza LYSINE RACEMASE
(Proteus
mirabilis) 		4 / 6 ALA A 312
LEU A 311
ILE A 351
SER A 287
 None
 0.90A 1sbrA-4dzaA:
undetectable
1sbrB-4dzaA:
undetectable		 1sbrA-4dzaA:
20.84
1sbrB-4dzaA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF8_0
(7-AMINO-ACTINOMYCIN
D)		 4dza LYSINE RACEMASE
(Proteus
mirabilis) 		3 / 3 THR A 250
THR A 248
PRO A 252
 None
 0.85A 1unjF-4dzaA:
undetectable		 1unjF-4dzaA:
8.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)		 4dza LYSINE RACEMASE
(Proteus
mirabilis) 		3 / 3 THR A 248
PRO A 252
THR A 250
 None
 0.86A 1unjL-4dzaA:
undetectable		 1unjL-4dzaA:
8.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 4dza LYSINE RACEMASE
(Proteus
mirabilis) 		3 / 3 THR A 248
PRO A 252
THR A 250
 None
 0.86A 1unmE-4dzaA:
undetectable		 1unmE-4dzaA:
8.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC2_0
(N8-ACTINOMYCIN D)		 4dza LYSINE RACEMASE
(Proteus
mirabilis) 		3 / 3 THR A 248
PRO A 252
THR A 250
 None
 0.77A 209dC-4dzaA:
undetectable		 209dC-4dzaA:
8.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA507_0
(CHORISMATE SYNTHASE)		 4dza LYSINE RACEMASE
(Proteus
mirabilis) 		3 / 3 LEU A 105
ASN A 101
ARG A 119
 None
 0.58A 2qhfA-4dzaA:
undetectable		 2qhfA-4dzaA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 4dza LYSINE RACEMASE
(Proteus
mirabilis) 		3 / 3 ASN A 133
ASN A 102
GLU A 138
 None
 0.94A 3kpdC-4dzaA:
undetectable		 3kpdC-4dzaA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_A_ADNA353_1
(ADENOSINE KINASE)		 4dza LYSINE RACEMASE
(Proteus
mirabilis) 		5 / 12 GLY A 170
GLY A 169
SER A 168
ASN A 167
GLY A 175
 None
 1.00A 3uboA-4dzaA:
2.4		 3uboA-4dzaA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHI_A_SAMA4001_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 4dza LYSINE RACEMASE
(Proteus
mirabilis) 		5 / 12 GLY A 336
GLY A 370
GLY A 373
THR A 280
GLU A 365
 None
 1.02A 5ehiA-4dzaA:
undetectable		 5ehiA-4dzaA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHI_C_SAMC4000_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 4dza LYSINE RACEMASE
(Proteus
mirabilis) 		5 / 12 GLY A 336
GLY A 370
GLY A 373
THR A 280
GLU A 365
 None
 1.05A 5ehiC-4dzaA:
undetectable		 5ehiC-4dzaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_B_C2FB402_1
(THYMIDYLATE SYNTHASE)		 4dza LYSINE RACEMASE
(Proteus
mirabilis) 		3 / 3 ASN A 244
ASP A 216
GLY A 169
 LLP  A  74 ( 4.5A)
None
None
 0.55A 5fctB-4dzaA:
undetectable		 5fctB-4dzaA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH614_0
(NADH DEHYDROGENASE,
PUTATIVE)		 4dza LYSINE RACEMASE
(Proteus
mirabilis) 		4 / 6 ILE A 201
VAL A 178
VAL A 227
SER A 168
 None
 0.73A 5jwaH-4dzaA:
undetectable		 5jwaH-4dzaA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MRA_B_DM2B204_1
(SORCIN)		 4dza LYSINE RACEMASE
(Proteus
mirabilis) 		4 / 6 TYR A  78
PHE A 265
ASP A  76
GLY A  79
 LLP  A  74 ( 4.4A)
None
None
None
 1.13A 5mraA-4dzaA:
undetectable
5mraB-4dzaA:
undetectable		 5mraA-4dzaA:
18.67
5mraB-4dzaA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 4dza LYSINE RACEMASE
(Proteus
mirabilis) 		4 / 7 ILE A 334
VAL A 352
ILE A 314
THR A 349
 None
 0.97A 6cduF-4dzaA:
undetectable
6cduG-4dzaA:
undetectable		 6cduF-4dzaA:
22.46
6cduG-4dzaA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBF_A_ACTA507_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 4dza LYSINE RACEMASE
(Proteus
mirabilis) 		3 / 3 LYS A 276
SER A  48
SER A  50
 None
 0.96A 6gbfA-4dzaA:
undetectable		 6gbfA-4dzaA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_1
(-)		 4dza LYSINE RACEMASE
(Proteus
mirabilis) 		5 / 12 GLY A  98
VAL A 136
GLY A  79
ASP A  81
ASN A 101
 None
 1.04A 6gngA-4dzaA:
undetectable		 6gngA-4dzaA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_D_AM2D301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 4dza LYSINE RACEMASE
(Proteus
mirabilis) 		4 / 8 ASP A 179
ARG A 219
ASP A 216
GLU A 215
 None
 1.04A 6mn4D-4dzaA:
undetectable		 6mn4D-4dzaA:
22.31