SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4dzh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_A_DCFA353_1
(ADENOSINE DEAMINASE)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 12 HIS A  78
HIS A 227
GLU A 230
HIS A 264
ASP A 315
 ZN  A 504 (-3.3A)
ZN  A 504 (-3.3A)
ZN  A 505 ( 4.2A)
ZN  A 505 ( 4.8A)
ZN  A 505 ( 2.0A)
 0.43A 1a4lA-4dzhA:
20.8		 1a4lA-4dzhA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_A_DCFA353_1
(ADENOSINE DEAMINASE)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 12 HIS A  80
HIS A 227
GLU A 230
HIS A 264
ASP A 315
 ZN  A 504 (-3.1A)
ZN  A 504 (-3.3A)
ZN  A 505 ( 4.2A)
ZN  A 505 ( 4.8A)
ZN  A 505 ( 2.0A)
 0.47A 1a4lA-4dzhA:
20.8		 1a4lA-4dzhA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_1
(ADENOSINE DEAMINASE)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		6 / 12 HIS A  80
LEU A  99
HIS A 227
GLU A 230
HIS A 264
ASP A 315
 ZN  A 504 (-3.1A)
None
ZN  A 504 (-3.3A)
ZN  A 505 ( 4.2A)
ZN  A 505 ( 4.8A)
ZN  A 505 ( 2.0A)
 0.78A 1a4lB-4dzhA:
20.7		 1a4lB-4dzhA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_1
(ADENOSINE DEAMINASE)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		6 / 12 HIS A  78
HIS A  80
HIS A 227
GLU A 230
HIS A 264
ASP A 315
 ZN  A 504 (-3.3A)
ZN  A 504 (-3.1A)
ZN  A 504 (-3.3A)
ZN  A 505 ( 4.2A)
ZN  A 505 ( 4.8A)
ZN  A 505 ( 2.0A)
 0.50A 1a4lC-4dzhA:
20.6		 1a4lC-4dzhA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_1
(ADENOSINE DEAMINASE)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 12 HIS A  80
HIS A 227
GLU A 230
HIS A 264
ASP A 315
 ZN  A 504 (-3.1A)
ZN  A 504 (-3.3A)
ZN  A 505 ( 4.2A)
ZN  A 505 ( 4.8A)
ZN  A 505 ( 2.0A)
 0.45A 1a4lD-4dzhA:
20.6		 1a4lD-4dzhA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4Y_A_TPVA501_1
(PROTEIN (HIV-1
PROTEASE))		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 10 ALA A 355
ILE A  25
GLY A 370
ILE A 369
VAL A 381
 None
 1.01A 1d4yA-4dzhA:
undetectable		 1d4yA-4dzhA:
12.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKO_A_EFZA999_1
(HIV-1 RT, A-CHAIN)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 10 LEU A 250
ASN A 257
VAL A 281
VAL A 224
LEU A 247
 None
 1.07A 1fkoA-4dzhA:
undetectable		 1fkoA-4dzhA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW3_A_SAMA500_0
(HISTONE
METHYLTRANSFERASE
DOT1L)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 12 GLY A 119
VAL A 148
ALA A 437
PHE A 115
ASN A  81
 None
 1.25A 1nw3A-4dzhA:
2.5		 1nw3A-4dzhA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 12 LEU A 352
ALA A 355
LEU A  74
ASN A  76
ALA A 332
 None
 1.14A 1sa1A-4dzhA:
2.6
1sa1B-4dzhA:
2.7		 1sa1A-4dzhA:
22.05
1sa1B-4dzhA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 12 LEU A 352
ALA A 355
LEU A  74
ASN A  76
ALA A 332
 None
 1.17A 1sa1C-4dzhA:
undetectable
1sa1D-4dzhA:
undetectable		 1sa1C-4dzhA:
22.05
1sa1D-4dzhA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 7 HIS A 227
ASP A 164
THR A 204
HIS A 225
 ZN  A 504 (-3.3A)
None
None
None
 1.43A 1v54A-4dzhA:
undetectable
1v54C-4dzhA:
undetectable		 1v54A-4dzhA:
20.88
1v54C-4dzhA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 7 HIS A 227
ASP A 164
THR A 204
HIS A 225
 ZN  A 504 (-3.3A)
None
None
None
 1.43A 1v55A-4dzhA:
undetectable
1v55C-4dzhA:
undetectable		 1v55A-4dzhA:
20.88
1v55C-4dzhA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1434_1
(CHITINASE)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		3 / 3 TRP A 104
THR A 204
TYR A 203
 None
 0.45A 2a3aA-4dzhA:
5.3		 2a3aA-4dzhA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2434_1
(CHITINASE)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		3 / 3 TRP A 104
THR A 204
TYR A 203
 None
 0.41A 2a3aB-4dzhA:
6.3		 2a3aB-4dzhA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1434_1
(CHITINASE)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		3 / 3 TRP A 104
THR A 204
TYR A 203
 None
 0.46A 2a3bA-4dzhA:
5.3		 2a3bA-4dzhA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 7 HIS A 227
ASP A 164
THR A 204
HIS A 225
 ZN  A 504 (-3.3A)
None
None
None
 1.43A 2dyrA-4dzhA:
undetectable
2dyrC-4dzhA:
undetectable		 2dyrA-4dzhA:
20.88
2dyrC-4dzhA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 6 HIS A 227
ASP A 164
THR A 204
HIS A 225
 ZN  A 504 (-3.3A)
None
None
None
 1.40A 2dysA-4dzhA:
undetectable
2dysC-4dzhA:
undetectable		 2dysA-4dzhA:
20.88
2dysC-4dzhA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 7 HIS A 227
ASP A 164
THR A 204
HIS A 225
 ZN  A 504 (-3.3A)
None
None
None
 1.43A 2eijA-4dzhA:
undetectable
2eijC-4dzhA:
undetectable		 2eijA-4dzhA:
20.88
2eijC-4dzhA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 7 HIS A 227
ASP A 164
THR A 204
HIS A 225
 ZN  A 504 (-3.3A)
None
None
None
 1.44A 2eijN-4dzhA:
undetectable
2eijP-4dzhA:
undetectable		 2eijN-4dzhA:
20.88
2eijP-4dzhA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 7 HIS A 227
ASP A 164
THR A 204
HIS A 225
 ZN  A 504 (-3.3A)
None
None
None
 1.40A 2eikA-4dzhA:
undetectable
2eikC-4dzhA:
undetectable		 2eikA-4dzhA:
20.88
2eikC-4dzhA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 7 HIS A 227
ASP A 164
THR A 204
HIS A 225
 ZN  A 504 (-3.3A)
None
None
None
 1.44A 2eikN-4dzhA:
undetectable
2eikP-4dzhA:
undetectable		 2eikN-4dzhA:
20.88
2eikP-4dzhA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 7 HIS A 227
ASP A 164
THR A 204
HIS A 225
 ZN  A 504 (-3.3A)
None
None
None
 1.40A 2eilA-4dzhA:
undetectable
2eilC-4dzhA:
undetectable		 2eilA-4dzhA:
20.88
2eilC-4dzhA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 7 HIS A 227
ASP A 164
THR A 204
HIS A 225
 ZN  A 504 (-3.3A)
None
None
None
 1.43A 2eilN-4dzhA:
undetectable
2eilP-4dzhA:
undetectable		 2eilN-4dzhA:
20.88
2eilP-4dzhA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 6 HIS A 227
ASP A 164
THR A 204
HIS A 225
 ZN  A 504 (-3.3A)
None
None
None
 1.36A 2eimA-4dzhA:
undetectable
2eimC-4dzhA:
undetectable		 2eimA-4dzhA:
20.88
2eimC-4dzhA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 6 HIS A 227
ASP A 164
THR A 204
HIS A 225
 ZN  A 504 (-3.3A)
None
None
None
 1.36A 2eimN-4dzhA:
undetectable
2eimP-4dzhA:
undetectable		 2eimN-4dzhA:
20.88
2eimP-4dzhA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 6 HIS A 227
ASP A 164
THR A 204
HIS A 225
 ZN  A 504 (-3.3A)
None
None
None
 1.37A 2einA-4dzhA:
undetectable
2einC-4dzhA:
undetectable		 2einA-4dzhA:
20.88
2einC-4dzhA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 6 HIS A 227
ASP A 164
THR A 204
HIS A 225
 ZN  A 504 (-3.3A)
None
None
None
 1.41A 2einN-4dzhA:
undetectable
2einP-4dzhA:
undetectable		 2einN-4dzhA:
20.88
2einP-4dzhA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_B_SAMB201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 12 GLY A 359
ALA A 362
GLY A 364
LEU A 310
THR A 351
 None
None
GOL  A 502 ( 4.2A)
None
None
 1.02A 2nyuB-4dzhA:
undetectable		 2nyuB-4dzhA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4P_A_TPVA300_1
(PROTEASE)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 11 ALA A 355
ILE A  25
GLY A 370
ILE A 369
VAL A 381
 None
 1.04A 2o4pA-4dzhA:
undetectable		 2o4pA-4dzhA:
12.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4S_A_AB1A400_2
(PROTEASE)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 12 ALA A 355
ILE A  25
GLY A 370
ILE A 369
VAL A 381
 None
 0.92A 2o4sB-4dzhA:
undetectable		 2o4sB-4dzhA:
12.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_A_HAEA502_1
(COLLAGENASE 3)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 6 LEU A 293
HIS A  78
HIS A  80
HIS A 227
 None
ZN  A 504 (-3.3A)
ZN  A 504 (-3.1A)
ZN  A 504 (-3.3A)
 0.91A 2ow9A-4dzhA:
undetectable		 2ow9A-4dzhA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGF_A_ADNA501_1
(ADENOSINE DEAMINASE)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		6 / 12 HIS A  80
HIS A 227
GLU A 230
HIS A 264
SER A 289
ASP A 315
 ZN  A 504 (-3.1A)
ZN  A 504 (-3.3A)
ZN  A 505 ( 4.2A)
ZN  A 505 ( 4.8A)
ZN  A 505 ( 4.0A)
ZN  A 505 ( 2.0A)
 0.36A 2pgfA-4dzhA:
21.5		 2pgfA-4dzhA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_1
(ADENOSINE DEAMINASE)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		6 / 12 HIS A  78
HIS A  80
HIS A 227
GLU A 230
HIS A 264
ASP A 315
 ZN  A 504 (-3.3A)
ZN  A 504 (-3.1A)
ZN  A 504 (-3.3A)
ZN  A 505 ( 4.2A)
ZN  A 505 ( 4.8A)
ZN  A 505 ( 2.0A)
 0.37A 2pgrA-4dzhA:
21.4		 2pgrA-4dzhA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_1
(ADENOSINE DEAMINASE)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 12 HIS A 227
HIS A 264
GLY A 313
HIS A  78
HIS A  80
 ZN  A 504 (-3.3A)
ZN  A 505 ( 4.8A)
None
ZN  A 504 (-3.3A)
ZN  A 504 (-3.1A)
 1.16A 2pgrA-4dzhA:
21.4		 2pgrA-4dzhA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		3 / 3 LEU A 247
PRO A 246
LEU A 250
 None
 0.53A 2po7B-4dzhA:
undetectable		 2po7B-4dzhA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0I_A_BEZA990_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 8 ASP A 315
HIS A 264
SER A 295
LEU A 293
 ZN  A 505 ( 2.0A)
ZN  A 505 ( 4.8A)
None
None
 0.91A 2q0iA-4dzhA:
undetectable		 2q0iA-4dzhA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0J_B_BEZB500_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 11 ASP A 315
HIS A  78
HIS A 264
SER A 295
LEU A 293
 ZN  A 505 ( 2.0A)
ZN  A 504 (-3.3A)
ZN  A 505 ( 4.8A)
None
None
 1.02A 2q0jB-4dzhA:
undetectable		 2q0jB-4dzhA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q5K_A_AB1A201_2
(PROTEASE)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 12 ALA A 355
ILE A  25
GLY A 370
ILE A 369
VAL A 381
 None
 0.95A 2q5kB-4dzhA:
undetectable		 2q5kB-4dzhA:
12.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CHDA1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 7 HIS A 227
ASP A 164
THR A 204
HIS A 225
 ZN  A 504 (-3.3A)
None
None
None
 1.42A 2y69A-4dzhA:
undetectable
2y69C-4dzhA:
undetectable		 2y69A-4dzhA:
20.88
2y69C-4dzhA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 6 HIS A 227
ASP A 164
THR A 204
HIS A 225
 ZN  A 504 (-3.3A)
None
None
None
 1.42A 2zxwA-4dzhA:
undetectable
2zxwC-4dzhA:
undetectable		 2zxwA-4dzhA:
20.88
2zxwC-4dzhA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 7 HIS A 227
ASP A 164
THR A 204
HIS A 225
 ZN  A 504 (-3.3A)
None
None
None
 1.42A 3abkA-4dzhA:
undetectable
3abkC-4dzhA:
undetectable		 3abkA-4dzhA:
20.88
3abkC-4dzhA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 7 HIS A 227
ASP A 164
THR A 204
HIS A 225
 ZN  A 504 (-3.3A)
None
None
None
 1.43A 3abkN-4dzhA:
undetectable
3abkP-4dzhA:
undetectable		 3abkN-4dzhA:
20.88
3abkP-4dzhA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 7 HIS A 227
ASP A 164
THR A 204
HIS A 225
 ZN  A 504 (-3.3A)
None
None
None
 1.42A 3abmN-4dzhA:
undetectable
3abmP-4dzhA:
undetectable		 3abmN-4dzhA:
20.88
3abmP-4dzhA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 6 HIS A 227
ASP A 164
THR A 204
HIS A 225
 ZN  A 504 (-3.3A)
None
None
None
 1.42A 3ag1A-4dzhA:
undetectable
3ag1C-4dzhA:
undetectable		 3ag1A-4dzhA:
20.88
3ag1C-4dzhA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 6 HIS A 227
ASP A 164
THR A 204
HIS A 225
 ZN  A 504 (-3.3A)
None
None
None
 1.44A 3ag1N-4dzhA:
undetectable
3ag1P-4dzhA:
undetectable		 3ag1N-4dzhA:
20.88
3ag1P-4dzhA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 7 HIS A 227
ASP A 164
THR A 204
HIS A 225
 ZN  A 504 (-3.3A)
None
None
None
 1.42A 3ag2A-4dzhA:
undetectable
3ag2C-4dzhA:
undetectable		 3ag2A-4dzhA:
20.88
3ag2C-4dzhA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 7 HIS A 227
ASP A 164
THR A 204
HIS A 225
 ZN  A 504 (-3.3A)
None
None
None
 1.43A 3ag2N-4dzhA:
undetectable
3ag2P-4dzhA:
undetectable		 3ag2N-4dzhA:
20.88
3ag2P-4dzhA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 7 HIS A 227
ASP A 164
THR A 204
HIS A 225
 ZN  A 504 (-3.3A)
None
None
None
 1.44A 3ag3A-4dzhA:
undetectable
3ag3C-4dzhA:
undetectable		 3ag3A-4dzhA:
20.88
3ag3C-4dzhA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 7 HIS A 227
ASP A 164
THR A 204
HIS A 225
 ZN  A 504 (-3.3A)
None
None
None
 1.41A 3ag3N-4dzhA:
undetectable
3ag3P-4dzhA:
undetectable		 3ag3N-4dzhA:
20.88
3ag3P-4dzhA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 7 HIS A 227
ASP A 164
THR A 204
HIS A 225
 ZN  A 504 (-3.3A)
None
None
None
 1.40A 3ag4A-4dzhA:
undetectable
3ag4C-4dzhA:
undetectable		 3ag4A-4dzhA:
20.88
3ag4C-4dzhA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 7 HIS A 227
ASP A 164
THR A 204
HIS A 225
 ZN  A 504 (-3.3A)
None
None
None
 1.41A 3ag4N-4dzhA:
undetectable
3ag4P-4dzhA:
undetectable		 3ag4N-4dzhA:
20.88
3ag4P-4dzhA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB5_0
(FERROCHELATASE)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		3 / 3 PRO A  82
LEU A  85
ARG A 443
 None
 0.72A 3aqiB-4dzhA:
undetectable		 3aqiB-4dzhA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 6 HIS A 227
ASP A 164
THR A 204
HIS A 225
 ZN  A 504 (-3.3A)
None
None
None
 1.40A 3asnA-4dzhA:
undetectable
3asnC-4dzhA:
undetectable		 3asnA-4dzhA:
20.88
3asnC-4dzhA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		3 / 3 LEU A 247
PRO A 246
LEU A 250
 None
 0.51A 3hcrA-4dzhA:
undetectable		 3hcrA-4dzhA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 11 THR A 350
ALA A 311
GLY A 358
THR A 356
ALA A 355
 None
 1.26A 3mg0H-4dzhA:
undetectable
3mg0I-4dzhA:
undetectable		 3mg0H-4dzhA:
18.24
3mg0I-4dzhA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_2
(PROTEASE)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 9 ALA A 355
ILE A  25
GLY A 370
ILE A 369
VAL A 381
 None
 1.08A 3ndwB-4dzhA:
undetectable		 3ndwB-4dzhA:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_1
(16S RRNA METHYLASE)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 5 ASN A 290
GLU A 126
THR A  84
SER A 295
 None
 1.46A 3p2kC-4dzhA:
undetectable		 3p2kC-4dzhA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TMZ_A_06XA504_1
(CYTOCHROME P450 2B4)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 9 LEU A 260
LEU A 250
ILE A 273
GLU A 272
VAL A 283
 None
 1.22A 3tmzA-4dzhA:
undetectable		 3tmzA-4dzhA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTP_A_017A201_1
(HIV-1 PROTEASE)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 10 GLY A  20
ALA A  68
ASP A  67
ASP A 384
LEU A 380
 None
 0.91A 3ttpA-4dzhA:
undetectable		 3ttpA-4dzhA:
11.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTP_A_017A201_2
(HIV-1 PROTEASE)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 10 GLY A  20
ALA A  68
ASP A  67
ASP A 384
LEU A 380
 None
 0.89A 3ttpB-4dzhA:
undetectable		 3ttpB-4dzhA:
11.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A202_2
(POL POLYPROTEIN)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 9 GLY A  20
ALA A  68
ASP A  67
ASP A 384
LEU A 380
 None
 0.96A 3u7sB-4dzhA:
undetectable		 3u7sB-4dzhA:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_1
(MNMC2)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 6 HIS A  80
ASP A  92
ASP A 315
ASN A 321
 ZN  A 504 (-3.1A)
None
ZN  A 505 ( 2.0A)
None
 0.93A 3vywA-4dzhA:
undetectable		 3vywA-4dzhA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 12 ILE A 193
VAL A 381
ILE A 124
LEU A 128
VAL A 412
 None
 1.07A 3w68C-4dzhA:
undetectable		 3w68C-4dzhA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6E_A_SAMA1349_0
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 12 PHE A 154
GLY A  73
ILE A 414
VAL A 412
ALA A 355
 None
 1.04A 4a6eA-4dzhA:
undetectable		 4a6eA-4dzhA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_1
(GUANINE DEAMINASE)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 12 HIS A 227
GLU A 230
GLU A 234
HIS A 264
ASP A 315
 ZN  A 504 (-3.3A)
ZN  A 505 ( 4.2A)
None
ZN  A 505 ( 4.8A)
ZN  A 505 ( 2.0A)
 0.68A 4aqlA-4dzhA:
44.7		 4aqlA-4dzhA:
27.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_1
(GUANINE DEAMINASE)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 12 HIS A 227
GLU A 230
HIS A 264
SER A 289
ASP A 315
 ZN  A 504 (-3.3A)
ZN  A 505 ( 4.2A)
ZN  A 505 ( 4.8A)
ZN  A 505 ( 4.0A)
ZN  A 505 ( 2.0A)
 0.35A 4aqlA-4dzhA:
44.7		 4aqlA-4dzhA:
27.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_1
(GUANINE DEAMINASE)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 12 LEU A  99
GLU A 107
ALA A 108
HIS A  80
ASP A 315
 None
None
None
ZN  A 504 (-3.1A)
ZN  A 505 ( 2.0A)
 1.37A 4aqlA-4dzhA:
44.7		 4aqlA-4dzhA:
27.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_1
(GUANINE DEAMINASE)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 12 LEU A  99
GLU A 230
HIS A 264
SER A 289
ASP A 315
 None
ZN  A 505 ( 4.2A)
ZN  A 505 ( 4.8A)
ZN  A 505 ( 4.0A)
ZN  A 505 ( 2.0A)
 0.64A 4aqlA-4dzhA:
44.7		 4aqlA-4dzhA:
27.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAQ_A_2GMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 6 ILE A 312
THR A 351
VAL A 135
ASP A 379
 None
 0.97A 4iaqA-4dzhA:
undetectable		 4iaqA-4dzhA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QDC_A_ASDA404_1
(3-KETOSTEROID
9ALPHA-HYDROXYLASE
OXYGENASE)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 12 VAL A 116
HIS A  80
GLN A 145
LEU A 157
ALA A 142
 None
ZN  A 504 (-3.1A)
None
None
None
 1.48A 4qdcA-4dzhA:
undetectable		 4qdcA-4dzhA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 12 HIS A  80
HIS A 227
HIS A 264
LEU A 293
ASP A 315
 ZN  A 504 (-3.1A)
ZN  A 504 (-3.3A)
ZN  A 505 ( 4.8A)
None
ZN  A 505 ( 2.0A)
 0.45A 4r88A-4dzhA:
33.6		 4r88A-4dzhA:
25.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_B_1LDB501_0
(CYTOSINE DEAMINASE)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 12 HIS A  80
HIS A 227
GLU A 230
LEU A 293
ASP A 315
 ZN  A 504 (-3.1A)
ZN  A 504 (-3.3A)
ZN  A 505 ( 4.2A)
None
ZN  A 505 ( 2.0A)
 0.53A 4r88B-4dzhA:
34.3		 4r88B-4dzhA:
25.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_C_1LDC501_0
(CYTOSINE DEAMINASE)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 12 HIS A  80
HIS A 227
GLU A 230
LEU A 293
ASP A 315
 ZN  A 504 (-3.1A)
ZN  A 504 (-3.3A)
ZN  A 505 ( 4.2A)
None
ZN  A 505 ( 2.0A)
 0.55A 4r88C-4dzhA:
33.7		 4r88C-4dzhA:
25.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_D_1LDD501_0
(CYTOSINE DEAMINASE)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 12 HIS A  80
HIS A 227
GLU A 230
LEU A 293
ASP A 315
 ZN  A 504 (-3.1A)
ZN  A 504 (-3.3A)
ZN  A 505 ( 4.2A)
None
ZN  A 505 ( 2.0A)
 0.54A 4r88D-4dzhA:
33.5		 4r88D-4dzhA:
25.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_E_1LDE501_0
(CYTOSINE DEAMINASE)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 12 HIS A  80
HIS A 227
GLU A 230
LEU A 293
ASP A 315
 ZN  A 504 (-3.1A)
ZN  A 504 (-3.3A)
ZN  A 505 ( 4.2A)
None
ZN  A 505 ( 2.0A)
 0.54A 4r88E-4dzhA:
33.5		 4r88E-4dzhA:
25.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_F_1LDF502_0
(CYTOSINE DEAMINASE)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 12 HIS A  80
HIS A 227
GLU A 230
LEU A 293
ASP A 315
 ZN  A 504 (-3.1A)
ZN  A 504 (-3.3A)
ZN  A 505 ( 4.2A)
None
ZN  A 505 ( 2.0A)
 0.56A 4r88F-4dzhA:
33.7		 4r88F-4dzhA:
25.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_1
(ESTROGEN RECEPTOR)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 12 THR A 120
LEU A 122
ALA A 123
LEU A 323
ARG A  87
 None
 0.98A 4xi3C-4dzhA:
undetectable		 4xi3C-4dzhA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 7 HIS A 227
ASP A 164
THR A 204
HIS A 225
 ZN  A 504 (-3.3A)
None
None
None
 1.42A 5b1aN-4dzhA:
undetectable
5b1aP-4dzhA:
undetectable		 5b1aN-4dzhA:
20.88
5b1aP-4dzhA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 7 HIS A 227
ASP A 164
THR A 204
HIS A 225
 ZN  A 504 (-3.3A)
None
None
None
 1.42A 5b1bN-4dzhA:
undetectable
5b1bP-4dzhA:
undetectable		 5b1bN-4dzhA:
20.88
5b1bP-4dzhA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 11 THR A 350
ALA A 311
GLY A 358
THR A 356
ALA A 355
 None
 1.25A 5bxnV-4dzhA:
undetectable
5bxnW-4dzhA:
undetectable		 5bxnV-4dzhA:
20.59
5bxnW-4dzhA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 4 LEU A 380
TYR A  21
PRO A  24
ILE A  25
 None
 1.40A 5esgA-4dzhA:
undetectable		 5esgA-4dzhA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_B_RBFB201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 12 GLU A 373
ASP A 367
GLY A 366
ALA A 311
ASN A 309
 None
 1.16A 5kbwB-4dzhA:
undetectable		 5kbwB-4dzhA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA601_0
(LACCASE 2)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 4 HIS A  80
HIS A 225
HIS A  78
HIS A 227
 ZN  A 504 (-3.1A)
None
ZN  A 504 (-3.3A)
ZN  A 504 (-3.3A)
 0.93A 5mhwA-4dzhA:
undetectable		 5mhwA-4dzhA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA601_0
(LACCASE 2)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 4 HIS A  80
HIS A 225
HIS A  78
HIS A 227
 ZN  A 504 (-3.1A)
None
ZN  A 504 (-3.3A)
ZN  A 504 (-3.3A)
 0.93A 5mhxA-4dzhA:
undetectable		 5mhxA-4dzhA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA601_0
(LACCASE 2)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 4 HIS A  80
HIS A 225
HIS A  78
HIS A 227
 ZN  A 504 (-3.1A)
None
ZN  A 504 (-3.3A)
ZN  A 504 (-3.3A)
 0.92A 5mhyA-4dzhA:
undetectable		 5mhyA-4dzhA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA601_0
(LACCASE 2)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 4 HIS A  80
HIS A 225
HIS A  78
HIS A 227
 ZN  A 504 (-3.1A)
None
ZN  A 504 (-3.3A)
ZN  A 504 (-3.3A)
 0.92A 5mhzA-4dzhA:
undetectable		 5mhzA-4dzhA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA601_0
(LACCASE 2)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 4 HIS A  80
HIS A 225
HIS A  78
HIS A 227
 ZN  A 504 (-3.1A)
None
ZN  A 504 (-3.3A)
ZN  A 504 (-3.3A)
 0.92A 5mi1A-4dzhA:
undetectable		 5mi1A-4dzhA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA601_0
(LACCASE 2)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 4 HIS A  80
HIS A 225
HIS A  78
HIS A 227
 ZN  A 504 (-3.1A)
None
ZN  A 504 (-3.3A)
ZN  A 504 (-3.3A)
 0.92A 5mi2A-4dzhA:
undetectable		 5mi2A-4dzhA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA601_0
(LACCASE 2)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 4 HIS A  80
HIS A 225
HIS A  78
HIS A 227
 ZN  A 504 (-3.1A)
None
ZN  A 504 (-3.3A)
ZN  A 504 (-3.3A)
 0.93A 5miaA-4dzhA:
undetectable		 5miaA-4dzhA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA601_0
(LACCASE 2)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 4 HIS A  80
HIS A 225
HIS A  78
HIS A 227
 ZN  A 504 (-3.1A)
None
ZN  A 504 (-3.3A)
ZN  A 504 (-3.3A)
 0.92A 5mibA-4dzhA:
undetectable		 5mibA-4dzhA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA601_0
(LACCASE 2)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 4 HIS A  80
HIS A 225
HIS A  78
HIS A 227
 ZN  A 504 (-3.1A)
None
ZN  A 504 (-3.3A)
ZN  A 504 (-3.3A)
 0.92A 5micA-4dzhA:
undetectable		 5micA-4dzhA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA601_0
(LACCASE 2)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 4 HIS A  80
HIS A 225
HIS A  78
HIS A 227
 ZN  A 504 (-3.1A)
None
ZN  A 504 (-3.3A)
ZN  A 504 (-3.3A)
 0.93A 5midA-4dzhA:
undetectable		 5midA-4dzhA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA601_0
(LACCASE 2)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 4 HIS A  80
HIS A 225
HIS A  78
HIS A 227
 ZN  A 504 (-3.1A)
None
ZN  A 504 (-3.3A)
ZN  A 504 (-3.3A)
 0.92A 5mieA-4dzhA:
undetectable		 5mieA-4dzhA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVS_A_ADNA401_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 7 GLY A 119
ALA A 437
PHE A 115
ASN A  81
 None
 0.76A 5mvsA-4dzhA:
undetectable		 5mvsA-4dzhA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVS_B_ADNB401_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 8 GLY A 119
ALA A 437
PHE A 115
ASN A  81
 None
 0.75A 5mvsB-4dzhA:
2.1		 5mvsB-4dzhA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 12 ILE A 401
VAL A  23
SER A 398
ALA A 348
ALA A 333
 None
 1.15A 5n0oB-4dzhA:
undetectable		 5n0oB-4dzhA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 6 HIS A 227
ASP A 164
THR A 204
HIS A 225
 ZN  A 504 (-3.3A)
None
None
None
 1.40A 5x19N-4dzhA:
undetectable
5x19P-4dzhA:
undetectable		 5x19N-4dzhA:
20.88
5x19P-4dzhA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_1
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		3 / 3 GLU A 107
TRP A  98
HIS A  80
 None
None
ZN  A 504 (-3.1A)
 0.92A 5xipA-4dzhA:
undetectable		 5xipA-4dzhA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_1
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		3 / 3 GLU A 230
TRP A  98
HIS A 200
 ZN  A 505 ( 4.2A)
None
None
 1.10A 5xipA-4dzhA:
undetectable		 5xipA-4dzhA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIL_B_TPVB201_0
(HIV-1 PROTEASE)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 12 ALA A 355
ILE A  25
GLY A 370
ILE A 369
VAL A 381
 None
 1.00A 6dilA-4dzhA:
undetectable		 6dilA-4dzhA:
10.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ1_B_AB1B201_1
(HIV-1 PROTEASE)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 12 ALA A 355
ILE A  25
GLY A 370
ILE A 369
VAL A 381
 None
 0.93A 6dj1B-4dzhA:
undetectable		 6dj1B-4dzhA:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ2_B_AB1B201_1
(HIV-1 PROTEASE)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 12 ALA A 355
ILE A  25
GLY A 370
ILE A 369
VAL A 381
 None
 0.92A 6dj2B-4dzhA:
undetectable		 6dj2B-4dzhA:
10.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N7F_A_RBFA502_0
(PUTATIVE GLUTATHIONE
REDUCTASE (GR))		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 7 GLY A 358
HIS A 225
ASN A 136
GLY A 313
 None
 0.88A 6n7fA-4dzhA:
undetectable		 6n7fA-4dzhA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_0
(ADENOSINE DEAMINASE)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 12 HIS A  80
HIS A 227
GLU A 230
HIS A 264
ASP A 315
 ZN  A 504 (-3.1A)
ZN  A 504 (-3.3A)
ZN  A 505 ( 4.2A)
ZN  A 505 ( 4.8A)
ZN  A 505 ( 2.0A)
 0.36A 6n91A-4dzhA:
21.7		 6n91A-4dzhA:
11.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_0
(ADENOSINE DEAMINASE)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 12 LEU A  99
HIS A 227
GLU A 230
HIS A 264
ASP A 315
 None
ZN  A 504 (-3.3A)
ZN  A 505 ( 4.2A)
ZN  A 505 ( 4.8A)
ZN  A 505 ( 2.0A)
 0.78A 6n91A-4dzhA:
21.7		 6n91A-4dzhA:
11.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_0
(ADENOSINE DEAMINASE)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		5 / 12 HIS A  80
HIS A 227
GLU A 230
HIS A 264
ASP A 315
 ZN  A 504 (-3.1A)
ZN  A 504 (-3.3A)
ZN  A 505 ( 4.2A)
ZN  A 505 ( 4.8A)
ZN  A 505 ( 2.0A)
 0.36A 6n91B-4dzhA:
21.6		 6n91B-4dzhA:
11.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 6 HIS A 227
ASP A 164
THR A 204
HIS A 225
 ZN  A 504 (-3.3A)
None
None
None
 1.44A 6nknA-4dzhA:
undetectable
6nknC-4dzhA:
undetectable		 6nknA-4dzhA:
20.88
6nknC-4dzhA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 7 HIS A 227
ASP A 164
THR A 204
HIS A 225
 ZN  A 504 (-3.3A)
None
None
None
 1.43A 6nmfN-4dzhA:
undetectable
6nmfP-4dzhA:
undetectable		 6nmfN-4dzhA:
20.88
6nmfP-4dzhA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4dzh AMIDOHYDROLASE
(Xanthomonas
campestris) 		4 / 7 HIS A 227
ASP A 164
THR A 204
HIS A 225
 ZN  A 504 (-3.3A)
None
None
None
 1.43A 6nmpN-4dzhA:
undetectable
6nmpP-4dzhA:
undetectable		 6nmpN-4dzhA:
20.88
6nmpP-4dzhA:
19.75