SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4e0q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TOP_B_ACRB1_2
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 4e0q COP9 SIGNALOSOME
COMPLEX SUBUNIT 6
(Drosophila
melanogaster) 		4 / 5 PRO A 178
ILE A  64
TRP A 137
PHE A 182
 None
 1.47A 3topB-4e0qA:
undetectable		 3topB-4e0qA:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_B_DXCB1473_0
(MJ0495-LIKE PROTEIN)		 4e0q COP9 SIGNALOSOME
COMPLEX SUBUNIT 6
(Drosophila
melanogaster) 		5 / 11 ILE A  86
GLY A  87
PHE A 100
SER A 171
GLY A 136
 None
 0.99A 4ac9B-4e0qA:
undetectable
4ac9C-4e0qA:
undetectable		 4ac9B-4e0qA:
16.44
4ac9C-4e0qA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOG_C_C2FC302_0
(THYMIDYLATE SYNTHASE)		 4e0q COP9 SIGNALOSOME
COMPLEX SUBUNIT 6
(Drosophila
melanogaster) 		5 / 11 ILE A  86
LEU A 167
GLY A  83
PHE A 100
VAL A  60
 None
 1.31A 4fogC-4e0qA:
undetectable		 4fogC-4e0qA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YSI_A_NCAA1001_0
(UBIQUITINATING/DEUBI
QUITINATING ENZYME
SDEA)		 4e0q COP9 SIGNALOSOME
COMPLEX SUBUNIT 6
(Drosophila
melanogaster) 		4 / 6 ARG A  92
GLY A  91
SER A  51
THR A  53
 None
 1.22A 5ysiA-4e0qA:
undetectable		 5ysiA-4e0qA:
21.21