SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4e1q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2M2P_B_DHIB24_0 (INSULIN B CHAIN)	4e1q	PEPTIDYL-PROLYL CIS-TRANS ISOMERASE (Triticum aestivum)	3 / 3	TYR A 55 GLY A 57 PHE A 74	None	0.63A	2m2pB-4e1qA: undetectable	2m2pB-4e1qA: 11.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KO0_O_TFPO201_1 (PROTEIN S100-A4)	4e1q	PEPTIDYL-PROLYL CIS-TRANS ISOMERASE (Triticum aestivum)	4 / 8	GLY A 82 CYH A 168 GLY A 71 PHE A 60	None	1.00A	3ko0O-4e1qA: undetectable 3ko0Q-4e1qA: undetectable	3ko0O-4e1qA: 17.26 3ko0Q-4e1qA: 17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A97_E_ZPCE1318_2 (CYS-LOOP LIGAND-GATED ION CHANNEL)	4e1q	PEPTIDYL-PROLYL CIS-TRANS ISOMERASE (Triticum aestivum)	4 / 6	TYR A 55 HIS A 54 VAL A 164 PHE A 119	None	1.21A	4a97E-4e1qA: undetectable	4a97E-4e1qA: 17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FA8_A_SAMA301_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE, PUTATIVE)	4e1q	PEPTIDYL-PROLYL CIS-TRANS ISOMERASE (Triticum aestivum)	5 / 12	GLY A 116 ILE A 85 ASN A 109 PHE A 36 LEU A 105	None	1.13A	5fa8A-4e1qA: undetectable	5fa8A-4e1qA: 23.50

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2M2P_B_DHIB24_0","INSULIN B CHAIN","4e1q","PEPTIDYL-PROLYL CIS-TRANS ISOMERASE","Triticum aestivum",3,"TYR A  55;GLY A  57;PHE A  74","None","0.63A","2m2pB-4e1qA:undetectable","2m2pB-4e1qA:11.33"],["3KO0_O_TFPO201_1","PROTEIN S100-A4;PROTEIN S100-A4","4e1q","PEPTIDYL-PROLYL CIS-TRANS ISOMERASE","Triticum aestivum",4,"GLY A  82;CYH A 168;GLY A  71;PHE A  60","None","1.00A","3ko0O-4e1qA:undetectable;3ko0Q-4e1qA:undetectable","3ko0O-4e1qA:17.26;3ko0Q-4e1qA:17.26"],["4A97_E_ZPCE1318_2","CYS-LOOP LIGAND-GATED ION CHANNEL","4e1q","PEPTIDYL-PROLYL CIS-TRANS ISOMERASE","Triticum aestivum",4,"TYR A  55;HIS A  54;VAL A 164;PHE A 119","None","1.21A","4a97E-4e1qA:undetectable","4a97E-4e1qA:17.59"],["5FA8_A_SAMA301_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE, PUTATIVE","4e1q","PEPTIDYL-PROLYL CIS-TRANS ISOMERASE","Triticum aestivum",5,"GLY A 116;ILE A  85;ASN A 109;PHE A  36;LEU A 105","None","1.13A","5fa8A-4e1qA:undetectable","5fa8A-4e1qA:23.50"]]