SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4e22'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTI_A_CCSA47_0 (GLUTATHIONE S-TRANSFERASE)	4e22	CYTIDYLATE KINASE (Yersinia pseudotuberculos is)	4 / 7	LEU A 224 LEU A 126 GLY A 125 LEU A 29	None	0.90A	1gtiA-4e22A: undetectable	1gtiA-4e22A: 24.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YFB_B_ACTB501_0 (METHYL-ACCEPTING CHEMOTAXIS TRANSDUCER)	4e22	CYTIDYLATE KINASE (Yersinia pseudotuberculos is)	4 / 6	ARG A 32 VAL A 72 ARG A 70 ILE A 81	None	1.12A	2yfbB-4e22A: undetectable	2yfbB-4e22A: 23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3S8P_A_SAMA500_1 (HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1)	4e22	CYTIDYLATE KINASE (Yersinia pseudotuberculos is)	3 / 3	HIS A 156 SER A 150 GLU A 153	None	0.92A	3s8pA-4e22A: undetectable	3s8pA-4e22A: 19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UR0_B_SVRB516_1 (RNA-DEPENDENT RNA POLYMERASE)	4e22	CYTIDYLATE KINASE (Yersinia pseudotuberculos is)	4 / 7	PRO A 13 GLY A 15 ALA A 16 ASP A 203	None SO4 A 301 (-3.2A) SO4 A 301 (-4.9A) None	0.63A	3ur0B-4e22A: undetectable	3ur0B-4e22A: 19.21

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1GTI_A_CCSA47_0","GLUTATHIONE S-TRANSFERASE","4e22","CYTIDYLATE KINASE","Yersinia pseudotuberculosis",4,"LEU A 224;LEU A 126;GLY A 125;LEU A  29","None","0.90A","1gtiA-4e22A:undetectable","1gtiA-4e22A:24.72"],["2YFB_B_ACTB501_0","METHYL-ACCEPTING CHEMOTAXIS TRANSDUCER","4e22","CYTIDYLATE KINASE","Yersinia pseudotuberculosis",4,"ARG A  32;VAL A  72;ARG A  70;ILE A  81","None","1.12A","2yfbB-4e22A:undetectable","2yfbB-4e22A:23.79"],["3S8P_A_SAMA500_1","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","4e22","CYTIDYLATE KINASE","Yersinia pseudotuberculosis",3,"HIS A 156;SER A 150;GLU A 153","None","0.92A","3s8pA-4e22A:undetectable","3s8pA-4e22A:19.59"],["3UR0_B_SVRB516_1","RNA-DEPENDENT RNA POLYMERASE","4e22","CYTIDYLATE KINASE","Yersinia pseudotuberculosis",4,"PRO A  13;GLY A  15;ALA A  16;ASP A 203","None;SO4 A 301 (-3.2A);SO4 A 301 (-4.9A);None","0.63A","3ur0B-4e22A:undetectable","3ur0B-4e22A:19.21"]]