SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4e2c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_B_ACTB201_0
(RETINOL-BINDING
PROTEIN 2)		 4e2c CHIMERIC WZZB CHAIN
LENGTH DETERMINANT
PROTEIN
(Shigella
flexneri;
Salmonella
enterica) 		4 / 5 TYR A 151
GLU A 117
LEU A 106
GLN A 113
 None
 1.04A 4qztB-4e2cA:
undetectable		 4qztB-4e2cA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_C_ADNC501_2
(-)		 4e2c CHIMERIC WZZB CHAIN
LENGTH DETERMINANT
PROTEIN
(Salmonella
enterica;
Shigella
flexneri) 		4 / 5 GLN A 145
THR A 284
THR A 120
GLY A 143
 None
 1.11A 6gbnC-4e2cA:
undetectable		 6gbnC-4e2cA:
21.03