SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4e2l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PMZ_E_TUBE220_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4e2l FERRIC ENTEROBACTIN
(ENTEROCHELIN)
TRANSPORT
(Escherichia
coli) 		4 / 6 TYR A 194
ILE A 195
SER A 124
SER A 123
 None
 1.15A 3pmzD-4e2lA:
undetectable		 3pmzD-4e2lA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_B_MN9B401_0
(N-ACETYLNEURAMINATE
LYASE)		 4e2l FERRIC ENTEROBACTIN
(ENTEROCHELIN)
TRANSPORT
(Escherichia
coli) 		4 / 6 SER A 175
LEU A 174
TYR A 191
LEU A 188
 None
 0.93A 4wozA-4e2lA:
undetectable
4wozB-4e2lA:
undetectable		 4wozA-4e2lA:
21.18
4wozB-4e2lA:
21.18