SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4e44'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1320_0
(CHLOROPEROXIDASE)		 4e44 CENTROMERE PROTEIN S
CENTROMERE PROTEIN X
(Homo
sapiens;
Homo
sapiens) 		4 / 6 ALA B  50
PHE A  42
ILE A  47
VAL A  27
 None
 0.91A 2cizA-4e44B:
undetectable		 2cizA-4e44B:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9W_A_PAUA6001_0
(PANTOTHENATE KINASE)		 4e44 CENTROMERE PROTEIN S
CENTROMERE PROTEIN X
(Homo
sapiens;
Homo
sapiens) 		5 / 11 VAL B  73
GLY B  53
THR A  46
ILE A  50
ARG B  52
 None
 1.33A 2f9wA-4e44B:
undetectable
2f9wB-4e44B:
undetectable		 2f9wA-4e44B:
17.60
2f9wB-4e44B:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 4e44 CENTROMERE PROTEIN S
CENTROMERE PROTEIN X
(Homo
sapiens) 		5 / 12 LEU B  74
CYH A  58
ALA B  49
VAL B  46
PHE B  10
 None
 1.28A 3b0wA-4e44B:
undetectable		 3b0wA-4e44B:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_B_PAUB248_0
(TYPE III
PANTOTHENATE KINASE)		 4e44 CENTROMERE PROTEIN S
CENTROMERE PROTEIN X
(Homo
sapiens;
Homo
sapiens) 		5 / 12 VAL B  73
VAL B  54
GLY B  53
THR A  46
ILE A  50
 None
 1.14A 3bf1A-4e44B:
undetectable
3bf1B-4e44B:
undetectable		 3bf1A-4e44B:
16.73
3bf1B-4e44B:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_2
(PROTEIN S100-A4)		 4e44 CENTROMERE PROTEIN S
(Homo
sapiens) 		3 / 3 GLU A  33
LEU A  36
ASP A  37
 None
 0.43A 3ko0T-4e44A:
undetectable		 3ko0T-4e44A:
20.69