SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4e4u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_B_EAAB224_1
(GLUTATHIONE
TRANSFERASE)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		5 / 12 GLY A 288
LEU A 117
VAL A 113
LEU A 366
ALA A 100
 None
 1.09A 1gseB-4e4uA:
undetectable		 1gseB-4e4uA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GX9_A_REAA1163_1
(BETA-LACTOGLOBULIN)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		5 / 11 LEU A 179
ILE A 218
GLU A 188
MET A 212
GLN A 178
 None
 1.37A 1gx9A-4e4uA:
undetectable		 1gx9A-4e4uA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Q_A_BEZA1501_0
(ANTHRANILATE
SYNTHASE)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		5 / 11 GLU A 266
GLY A 258
THR A 257
LEU A  88
GLU A 234
 None
 1.40A 1i7qA-4e4uA:
undetectable		 1i7qA-4e4uA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		4 / 6 GLY A 313
PRO A 314
ILE A 368
GLY A 316
 None
 0.85A 1usqB-4e4uA:
undetectable		 1usqB-4e4uA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		4 / 6 GLY A 313
PRO A 314
ILE A 368
GLY A 316
 None
 0.85A 1usqC-4e4uA:
undetectable		 1usqC-4e4uA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2002_1
(SERUM ALBUMIN)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		4 / 8 ALA A 256
ALA A 307
GLU A 334
LEU A 261
 None
 0.78A 2bxgA-4e4uA:
undetectable		 2bxgA-4e4uA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_A_ACHA546_0
(ACETYLCHOLINESTERASE)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		4 / 8 TYR A  41
TYR A 128
HIS A 209
GLY A 207
 None
 1.06A 2ha4A-4e4uA:
undetectable		 2ha4A-4e4uA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_B_ACHB603_0
(ACETYLCHOLINESTERASE)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		4 / 7 TYR A  41
TYR A 128
HIS A 209
GLY A 207
 None
 1.06A 2ha4B-4e4uA:
2.1		 2ha4B-4e4uA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_A_CLMA1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		4 / 6 GLY A 313
PRO A 314
ILE A 368
GLY A 316
 None
 0.84A 2jkjA-4e4uA:
undetectable		 2jkjA-4e4uA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_B_CLMB1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		4 / 6 GLY A 313
PRO A 314
ILE A 368
GLY A 316
 None
 0.84A 2jkjB-4e4uA:
undetectable		 2jkjB-4e4uA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_C_CLMC1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		4 / 6 GLY A 313
PRO A 314
ILE A 368
GLY A 316
 None
 0.84A 2jkjC-4e4uA:
undetectable		 2jkjC-4e4uA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_E_CLME1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		4 / 7 GLY A 313
PRO A 314
ILE A 368
GLY A 316
 None
 0.84A 2jkjE-4e4uA:
undetectable		 2jkjE-4e4uA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_B_CLMB1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		4 / 6 GLY A 313
PRO A 314
ILE A 368
GLY A 316
 None
 0.83A 2jklB-4e4uA:
undetectable		 2jklB-4e4uA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		4 / 7 GLY A 313
PRO A 314
ILE A 368
GLY A 316
 None
 0.84A 2jklE-4e4uA:
undetectable		 2jklE-4e4uA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_A_DVAA6_0
(GRAMICIDIN A)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		4 / 5 ALA A 317
VAL A 315
TRP A  23
TRP A 339
 None
 1.45A 2xdcA-4e4uA:
undetectable
2xdcB-4e4uA:
undetectable		 2xdcA-4e4uA:
4.02
2xdcB-4e4uA:
4.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_B_DVAB6_0
(GRAMICIDIN A)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		4 / 5 TRP A  23
TRP A 339
ALA A 317
VAL A 315
 None
 1.43A 2xdcA-4e4uA:
undetectable
2xdcB-4e4uA:
undetectable		 2xdcA-4e4uA:
4.02
2xdcB-4e4uA:
4.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_D_DVAD6_0
(GRAMICIDIN A)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		4 / 5 TRP A  23
TRP A 339
ALA A 317
VAL A 315
 None
 1.29A 2xdcC-4e4uA:
undetectable
2xdcD-4e4uA:
undetectable		 2xdcC-4e4uA:
4.02
2xdcD-4e4uA:
4.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_F_DVAF6_0
(GRAMICIDIN A)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		4 / 5 TRP A  23
TRP A 339
ALA A 317
VAL A 315
 None
 1.29A 2xdcE-4e4uA:
undetectable
2xdcF-4e4uA:
undetectable		 2xdcE-4e4uA:
4.02
2xdcF-4e4uA:
4.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA6_0
(VAL-GRAMICIDIN A)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		4 / 5 ALA A 317
VAL A 315
TRP A  23
TRP A 339
 None
 1.40A 2y5mA-4e4uA:
undetectable
2y5mB-4e4uA:
undetectable		 2y5mA-4e4uA:
4.02
2y5mB-4e4uA:
4.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_B_DVAB6_0
(VAL-GRAMICIDIN A)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		4 / 5 TRP A  23
TRP A 339
ALA A 317
VAL A 315
 None
 1.39A 2y5mA-4e4uA:
undetectable
2y5mB-4e4uA:
undetectable		 2y5mA-4e4uA:
4.02
2y5mB-4e4uA:
4.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_D_DVAD6_0
(VAL-GRAMICIDIN A)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		4 / 5 TRP A  23
TRP A 339
ALA A 317
VAL A 315
 None
 1.31A 2y5mC-4e4uA:
undetectable
2y5mD-4e4uA:
undetectable		 2y5mC-4e4uA:
4.02
2y5mD-4e4uA:
4.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_F_DVAF6_0
(VAL-GRAMICIDIN A)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		4 / 5 TRP A  23
TRP A 339
ALA A 317
VAL A 315
 None
 1.30A 2y5mE-4e4uA:
undetectable
2y5mF-4e4uA:
undetectable		 2y5mE-4e4uA:
4.02
2y5mF-4e4uA:
4.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA6_0
(VAL-GRAMICIDIN A)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		4 / 5 ALA A 317
VAL A 315
TRP A  23
TRP A 339
 None
 1.41A 2y6nA-4e4uA:
undetectable
2y6nB-4e4uA:
undetectable		 2y6nA-4e4uA:
4.02
2y6nB-4e4uA:
4.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_B_DVAB6_0
(VAL-GRAMICIDIN A)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		4 / 5 TRP A  23
TRP A 339
ALA A 317
VAL A 315
 None
 1.39A 2y6nA-4e4uA:
undetectable
2y6nB-4e4uA:
undetectable		 2y6nA-4e4uA:
4.02
2y6nB-4e4uA:
4.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_D_DVAD6_0
(VAL-GRAMICIDIN A)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		4 / 5 TRP A  23
TRP A 339
ALA A 317
VAL A 315
 None
 1.29A 2y6nC-4e4uA:
undetectable
2y6nD-4e4uA:
undetectable		 2y6nC-4e4uA:
4.02
2y6nD-4e4uA:
4.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_F_DVAF6_0
(VAL-GRAMICIDIN A)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		4 / 5 TRP A  23
TRP A 339
ALA A 317
VAL A 315
 None
 1.29A 2y6nE-4e4uA:
undetectable
2y6nF-4e4uA:
undetectable		 2y6nE-4e4uA:
4.02
2y6nF-4e4uA:
4.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZG_B_NCAB302_0
(ADP-RIBOSYL CYCLASE
1)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		4 / 7 LEU A 158
ASP A 355
TRP A 353
THR A 129
 DTU  A 501 (-4.4A)
None
None
None
 1.08A 3dzgB-4e4uA:
2.3		 3dzgB-4e4uA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_A_KKKA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		5 / 12 PHE A 267
GLY A 287
ALA A 292
ILE A 306
ILE A 278
 None
 1.08A 3ld6A-4e4uA:
undetectable		 3ld6A-4e4uA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SM2_A_478A126_2
(GAG-PRO-POL
POLYPROTEIN)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		5 / 11 ALA A 100
VAL A 113
GLY A 106
ALA A 108
LEU A 289
 None
 0.97A 3sm2B-4e4uA:
undetectable		 3sm2B-4e4uA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_B_DXCB1473_0
(MJ0495-LIKE PROTEIN)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		5 / 11 ILE A 351
ILE A 368
GLY A 367
SER A  95
GLY A  38
 None
 1.06A 4ac9B-4e4uA:
2.1
4ac9C-4e4uA:
2.0		 4ac9B-4e4uA:
22.24
4ac9C-4e4uA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		5 / 9 ASP A 103
ILE A 104
GLY A  36
THR A  30
GLY A  33
 None
 1.22A 4acaB-4e4uA:
2.2
4acaC-4e4uA:
undetectable		 4acaB-4e4uA:
22.24
4acaC-4e4uA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C2P_A_X8ZA709_1
(ANGIOTENSIN-CONVERTI
NG ENZYME)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		5 / 11 HIS A 209
GLU A 259
HIS A 309
GLU A 334
TYR A 130
 None
 1.50A 4c2pA-4e4uA:
undetectable		 4c2pA-4e4uA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_1
(METHYLTRANSFERASE
NSUN4)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		3 / 3 ASP A 146
ARG A 193
ASP A 141
 None
 0.73A 4fp9A-4e4uA:
undetectable		 4fp9A-4e4uA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_1
(METHYLTRANSFERASE
NSUN4)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		3 / 3 ASP A 146
ARG A 193
ASP A 141
 None
 0.70A 4fp9C-4e4uA:
undetectable		 4fp9C-4e4uA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_1
(METHYLTRANSFERASE
NSUN4)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		3 / 3 ASP A 146
ARG A 193
ASP A 141
 None
 0.72A 4fp9F-4e4uA:
undetectable		 4fp9F-4e4uA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD4_C_AOQC4003_1
(CYTOCHROME B)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		5 / 12 PHE A  25
GLY A 313
ILE A 351
LEU A 370
LEU A 366
 None
 0.98A 4pd4C-4e4uA:
undetectable		 4pd4C-4e4uA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		5 / 12 ASP A 103
VAL A  37
SER A 320
GLY A 365
GLY A 316
 None
 1.38A 4pevB-4e4uA:
undetectable		 4pevB-4e4uA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_B_IMNB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		5 / 11 GLY A  92
ALA A 100
LEU A   6
ILE A  24
MET A  50
 None
 1.16A 4xumB-4e4uA:
undetectable		 4xumB-4e4uA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESK_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		5 / 12 GLY A 356
TYR A 132
LEU A 131
GLY A 207
THR A 161
 None
 1.14A 5eskA-4e4uA:
undetectable		 5eskA-4e4uA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G48_A_1FLA1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		4 / 8 THR A 262
LEU A 281
ILE A 295
LEU A 279
 None
 0.87A 5g48A-4e4uA:
undetectable		 5g48A-4e4uA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_1
(CDL2.2)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		5 / 10 ILE A   3
PRO A  67
LEU A 366
PRO A 364
LEU A   6
 None
 1.17A 5ienB-4e4uA:
undetectable		 5ienB-4e4uA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_B_ACTB401_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT
N6-ADENOSINE-METHYLT
RANSFERASE SUBUNIT
METTL14)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		4 / 6 GLU A 259
ARG A 260
LEU A 261
ARG A 285
 None
 1.10A 5l6eA-4e4uA:
undetectable
5l6eB-4e4uA:
undetectable		 5l6eA-4e4uA:
19.51
5l6eB-4e4uA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA504_1
(-)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		4 / 8 ILE A 253
GLU A 233
THR A 208
LEU A 205
 None
 0.73A 5og9A-4e4uA:
undetectable		 5og9A-4e4uA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FHW_A_ACRA801_2
(GLUCOAMYLASE P)		 4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(unidentified) 		3 / 3 TRP A 231
GLU A 234
GLU A 334
 None
 0.96A 6fhwA-4e4uA:
undetectable		 6fhwA-4e4uA:
12.86