SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4e6u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_A_MK1A401_2
(HIV-II PROTEASE)		 4e6u ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Acinetobacter
baumannii) 		5 / 9 ALA A  17
ILE A  37
ILE A  30
ILE A   7
ILE A  19
 None
 0.95A 1hshB-4e6uA:
undetectable		 1hshB-4e6uA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_B_RITB301_1
(PROTEASE)		 4e6u ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Acinetobacter
baumannii) 		4 / 7 ASP A  22
ILE A  61
ALA A  11
ILE A   7
 None
 0.79A 1n49A-4e6uA:
undetectable		 1n49A-4e6uA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2REZ_A_ACTA155_0
(MULTIFUNCTIONAL
CYCLASE-DEHYDRATASE-
3-O-METHYL
TRANSFERASE TCMN)		 4e6u ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Acinetobacter
baumannii) 		4 / 5 ARG A  99
GLY A  32
PRO A  33
PHE A  52
 None
 0.89A 2rezA-4e6uA:
undetectable		 2rezA-4e6uA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_2
(PROTEASE RETROPEPSIN)		 4e6u ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Acinetobacter
baumannii) 		5 / 12 ALA A  17
ILE A  37
VAL A  49
ILE A  12
ILE A  19
 None
 0.93A 2rkgB-4e6uA:
undetectable		 2rkgB-4e6uA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E00_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4e6u ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Acinetobacter
baumannii) 		5 / 12 ILE A 221
ALA A 231
GLN A 234
VAL A 184
ILE A 196
 None
 1.02A 3e00A-4e6uA:
undetectable		 3e00A-4e6uA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_H_SAMH300_0
(PUTATIVE RRNA
METHYLASE)		 4e6u ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Acinetobacter
baumannii) 		5 / 12 GLY A  86
ASN A  87
ASN A  88
GLY A  68
ASN A 114
 None
 1.17A 3eeyH-4e6uA:
undetectable		 3eeyH-4e6uA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_I_SAMI300_0
(PUTATIVE RRNA
METHYLASE)		 4e6u ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Acinetobacter
baumannii) 		5 / 12 GLY A  86
ASN A  87
ASN A  88
GLY A  68
ASN A 114
 None
 1.15A 3eeyI-4e6uA:
undetectable		 3eeyI-4e6uA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FAL_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4e6u ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Acinetobacter
baumannii) 		5 / 10 ILE A 221
ALA A 231
GLN A 234
VAL A 184
ILE A 196
 None
 1.00A 3falA-4e6uA:
undetectable		 3falA-4e6uA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_1
(PROTEASE)		 4e6u ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Acinetobacter
baumannii) 		6 / 9 ALA A  17
ILE A  37
VAL A  49
ILE A  12
ILE A   7
ILE A  19
 None
 1.16A 3s43A-4e6uA:
undetectable		 3s43A-4e6uA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_0
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 4e6u ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Acinetobacter
baumannii) 		5 / 12 ALA A 186
GLY A 195
ALA A 217
PRO A 181
LEU A 253
 None
 0.99A 3tm4A-4e6uA:
undetectable		 3tm4A-4e6uA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_B_SAMB401_0
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 4e6u ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Acinetobacter
baumannii) 		5 / 12 ALA A 186
GLY A 195
ALA A 217
PRO A 181
LEU A 253
 None
 1.03A 3tm4B-4e6uA:
undetectable		 3tm4B-4e6uA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGJ_A_1PQA304_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4e6u ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Acinetobacter
baumannii) 		4 / 8 ILE A  31
TRP A  82
GLY A  68
GLU A  69
 None
None
None
SO4  A 302 ( 4.3A)
 0.98A 4fgjA-4e6uA:
undetectable
4fgjB-4e6uA:
undetectable		 4fgjA-4e6uA:
21.30
4fgjB-4e6uA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVD_A_SAMA502_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 4e6u ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Acinetobacter
baumannii) 		5 / 12 ILE A 158
HIS A 143
VAL A 144
HIS A 145
ILE A 146
 None
 0.65A 4rvdA-4e6uA:
undetectable		 4rvdA-4e6uA:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_A_SALA801_1
(PROTEIN POLYBROMO-1)		 4e6u ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Acinetobacter
baumannii) 		4 / 7 ILE A 235
LEU A 214
TYR A 183
ILE A 250
 None
 0.80A 4y03A-4e6uA:
undetectable		 4y03A-4e6uA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB202_0
(HYDROXYNITRILE LYASE)		 4e6u ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Acinetobacter
baumannii) 		4 / 7 VAL A 128
LEU A 116
VAL A 138
THR A 120
 None
 1.03A 5e4dA-4e6uA:
undetectable
5e4dB-4e6uA:
undetectable		 5e4dA-4e6uA:
21.99
5e4dB-4e6uA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_D_ILED602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4e6u ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Acinetobacter
baumannii) 		5 / 6 ILE A  55
ALA A  17
THR A  36
VAL A  35
VAL A  23
 None
 1.26A 5eclD-4e6uA:
undetectable		 5eclD-4e6uA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUN_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 4e6u ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Acinetobacter
baumannii) 		5 / 9 ILE A 158
ILE A 164
ILE A 146
ASN A 132
ALA A 135
 None
None
None
None
EDO  A 309 ( 4.0A)
 0.98A 5nunA-4e6uA:
undetectable		 5nunA-4e6uA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_3
(-)		 4e6u ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Acinetobacter
baumannii) 		3 / 3 ASP A 165
ASP A 130
ASN A  59
 None
 0.84A 6gngB-4e6uA:
undetectable		 6gngB-4e6uA:
18.30