SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4e6z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_B_CCSB417_0
(ESTROGEN RECEPTOR)		 4e6z APICOPLAST TIC22,
PUTATIVE
(Plasmodium
falciparum) 		4 / 6 PRO A 193
PHE A 195
GLN A 174
VAL A 258
 None
 1.39A 1l2iB-4e6zA:
undetectable		 1l2iB-4e6zA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA2_0
(FERROCHELATASE)		 4e6z APICOPLAST TIC22,
PUTATIVE
(Plasmodium
falciparum) 		4 / 8 MET A 135
LEU A 168
SER A 263
VAL A 194
 None
 1.17A 2qd2A-4e6zA:
undetectable		 2qd2A-4e6zA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_1
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 4e6z APICOPLAST TIC22,
PUTATIVE
(Plasmodium
falciparum) 		4 / 5 GLN A 262
SER A 263
ASP A 108
ASP A 115
 None
 1.41A 4qtuB-4e6zA:
undetectable		 4qtuB-4e6zA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_D_SAMD301_1
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 4e6z APICOPLAST TIC22,
PUTATIVE
(Plasmodium
falciparum) 		4 / 5 GLN A 262
SER A 263
ASP A 108
ASP A 115
 None
 1.31A 4qtuD-4e6zA:
undetectable		 4qtuD-4e6zA:
20.00