SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4e72'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_D_BRLD503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 4e72 UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 4 ILE A  69
LEU A  31
VAL A 121
ILE A 123
 None
 0.90A 1fm6D-4e72A:
undetectable		 1fm6D-4e72A:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2001_1
(SERUM ALBUMIN)		 4e72 UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 ALA A 166
PHE A 167
ALA A 171
LEU A 211
 None
 0.94A 2bxmA-4e72A:
undetectable		 2bxmA-4e72A:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JC9_A_ADNA1497_1
(CYTOSOLIC PURINE
5'-NUCLEOTIDASE)		 4e72 UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 ASP A 214
THR A 199
ASN A 144
PHE A 142
 None
 1.25A 2jc9A-4e72A:
undetectable		 2jc9A-4e72A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_D_9PLD1_1
(CYTOCHROME P450 2A13)		 4e72 UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 PHE A 167
ALA A 174
ALA A 208
THR A 205
 None
 0.88A 3t3sD-4e72A:
undetectable		 3t3sD-4e72A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_F_9PLF1_1
(CYTOCHROME P450 2A13)		 4e72 UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 PHE A 167
ALA A 174
ALA A 208
THR A 205
 None
 0.85A 3t3sF-4e72A:
undetectable		 3t3sF-4e72A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_B_SALB1345_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4e72 UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 LEU A 155
VAL A 239
LEU A 235
ALA A 166
 None
 0.91A 3uniB-4e72A:
undetectable		 3uniB-4e72A:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQY_A_BEZA401_0
(THIOREDOXIN)		 4e72 UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 ILE A 238
PHE A 167
VAL A 239
GLN A 156
 None
 0.97A 5dqyA-4e72A:
undetectable		 5dqyA-4e72A:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_2
(ADENOSINE KINASE)		 4e72 UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 4 ASN A  54
LEU A  52
SER A 107
LEU A  98
 None
 1.34A 5kb5A-4e72A:
undetectable		 5kb5A-4e72A:
22.49