SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4e74'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB203_0
(HYDROXYNITRILE LYASE)		 4e74 PLEXIN-A4
(Homo
sapiens) 		4 / 4 VAL A1589
ALA A1585
ILE A1525
THR A1583
 None
 1.09A 5e4dB-4e74A:
undetectable		 5e4dB-4e74A:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		 4e74 PLEXIN-A4
(Homo
sapiens) 		4 / 6 LEU A1584
MET A1563
THR A1571
LEU A1581
 None
None
UNX  A1704 ( 4.4A)
None
 1.06A 6mvxA-4e74A:
undetectable
6mvxB-4e74A:
undetectable
6mvxC-4e74A:
undetectable		 6mvxA-4e74A:
14.54
6mvxB-4e74A:
14.54
6mvxC-4e74A:
14.54