SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4e8u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DBB_H_STRH229_1 (IGG1-KAPPA DB3 FAB (HEAVY CHAIN) IGG1-KAPPA DB3 FAB (LIGHT CHAIN))	4e8u	PUTATIVE UNCHARACTERIZED PROTEIN T8P19.180 (Arabidopsis thaliana)	4 / 8	GLY A 236 ASN A 238 GLY A 241 VAL A 136	None	0.85A	1dbbH-4e8uA: undetectable 1dbbL-4e8uA: undetectable	1dbbH-4e8uA: 20.70 1dbbL-4e8uA: 17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RU9_H_BEZH601_0 (IMMUNOGLOBULIN IGG2A, HEAVY CHAIN IMMUNOGLOBULIN IGG2A, LIGHT CHAIN)	4e8u	PUTATIVE UNCHARACTERIZED PROTEIN T8P19.180 (Arabidopsis thaliana)	5 / 9	ALA A 203 TYR A 204 GLY A 197 PHE A 187 GLY A 133	None	1.16A	1ru9H-4e8uA: undetectable 1ru9L-4e8uA: undetectable	1ru9H-4e8uA: 19.65 1ru9L-4e8uA: 21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RUA_H_BEZH601_0 (IMMUNOGLOBULIN IGG2A, HEAVY CHAIN IMMUNOGLOBULIN IGG2A, LIGHT CHAIN)	4e8u	PUTATIVE UNCHARACTERIZED PROTEIN T8P19.180 (Arabidopsis thaliana)	5 / 10	ALA A 203 TYR A 204 GLY A 197 PHE A 187 GLY A 133	None	1.18A	1ruaH-4e8uA: undetectable 1ruaL-4e8uA: undetectable	1ruaH-4e8uA: 19.65 1ruaL-4e8uA: 21.17

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DBB_H_STRH229_1","IGG1-KAPPA DB3 FAB (HEAVY CHAIN);IGG1-KAPPA DB3 FAB (LIGHT CHAIN)","4e8u","PUTATIVE UNCHARACTERIZED PROTEIN T8P19.180","Arabidopsis thaliana",4,"GLY A 236;ASN A 238;GLY A 241;VAL A 136","None","0.85A","1dbbH-4e8uA:undetectable;1dbbL-4e8uA:undetectable","1dbbH-4e8uA:20.70;1dbbL-4e8uA:17.89"],["1RU9_H_BEZH601_0","IMMUNOGLOBULIN IGG2A, HEAVY CHAIN;IMMUNOGLOBULIN IGG2A, LIGHT CHAIN","4e8u","PUTATIVE UNCHARACTERIZED PROTEIN T8P19.180","Arabidopsis thaliana",5,"ALA A 203;TYR A 204;GLY A 197;PHE A 187;GLY A 133","None","1.16A","1ru9H-4e8uA:undetectable;1ru9L-4e8uA:undetectable","1ru9H-4e8uA:19.65;1ru9L-4e8uA:21.17"],["1RUA_H_BEZH601_0","IMMUNOGLOBULIN IGG2A, HEAVY CHAIN;IMMUNOGLOBULIN IGG2A, LIGHT CHAIN","4e8u","PUTATIVE UNCHARACTERIZED PROTEIN T8P19.180","Arabidopsis thaliana",5,"ALA A 203;TYR A 204;GLY A 197;PHE A 187;GLY A 133","None","1.18A","1ruaH-4e8uA:undetectable;1ruaL-4e8uA:undetectable","1ruaH-4e8uA:19.65;1ruaL-4e8uA:21.17"]]