SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4e9l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_C_SPMC1434_1
(NITROALKANE OXIDASE)		 4e9l ATTACHING AND
EFFACING PROTEIN,
PATHOGENESIS FACTOR
(Escherichia
coli) 		5 / 12 LEU A 960
ALA A 936
SER A 970
LEU A 987
VAL A 986
 None
 1.22A 2c12C-4e9lA:
undetectable		 2c12C-4e9lA:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H4J_A_NCAA1002_0
(NAD-DEPENDENT
DEACETYLASE)		 4e9l ATTACHING AND
EFFACING PROTEIN,
PATHOGENESIS FACTOR
(Escherichia
coli) 		4 / 5 ALA A 758
ASN A 818
ILE A 820
ASP A 814
 None
 1.08A 2h4jA-4e9lA:
undetectable		 2h4jA-4e9lA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AF0_A_MOAA1526_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 4e9l ATTACHING AND
EFFACING PROTEIN,
PATHOGENESIS FACTOR
(Escherichia
coli) 		4 / 8 SER A 933
SER A 970
GLY A 967
GLN A 968
 None
 1.00A 4af0A-4e9lA:
undetectable		 4af0A-4e9lA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4e9l ATTACHING AND
EFFACING PROTEIN,
PATHOGENESIS FACTOR
(Escherichia
coli) 		4 / 8 GLY A 701
GLY A 700
VAL A 699
ASP A 814
 None
 0.81A 4qvvK-4e9lA:
undetectable
4qvvL-4e9lA:
undetectable		 4qvvK-4e9lA:
21.36
4qvvL-4e9lA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4e9l ATTACHING AND
EFFACING PROTEIN,
PATHOGENESIS FACTOR
(Escherichia
coli) 		4 / 8 GLY A 701
GLY A 700
VAL A 699
ASP A 814
 None
 0.82A 4qvvY-4e9lA:
undetectable
4qvvZ-4e9lA:
undetectable		 4qvvY-4e9lA:
21.36
4qvvZ-4e9lA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2O_A_ACTA1728_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9)		 4e9l ATTACHING AND
EFFACING PROTEIN,
PATHOGENESIS FACTOR
(Escherichia
coli) 		4 / 5 THR A 747
TRP A 748
ASP A 742
ASN A 743
 None
 1.48A 5b2oA-4e9lA:
0.0		 5b2oA-4e9lA:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2P_A_ACTA1728_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9)		 4e9l ATTACHING AND
EFFACING PROTEIN,
PATHOGENESIS FACTOR
(Escherichia
coli) 		4 / 5 THR A 747
TRP A 748
ASP A 742
ASN A 743
 None
 1.46A 5b2pA-4e9lA:
0.0		 5b2pA-4e9lA:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2Q_A_ACTA1729_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9)		 4e9l ATTACHING AND
EFFACING PROTEIN,
PATHOGENESIS FACTOR
(Escherichia
coli) 		4 / 5 THR A 747
TRP A 748
ASP A 742
ASN A 743
 None
 1.46A 5b2qA-4e9lA:
0.0		 5b2qA-4e9lA:
13.42