SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4e9x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_B_ESTB354_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 8 SER A1232
VAL A1231
TYR A1224
MET A1210
 None
 1.08A 1fduB-4e9xA:
undetectable		 1fduB-4e9xA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA8_0
(GRAMICIDIN A)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		3 / 4 VAL A1064
TRP A1102
TRP A1061
 None
CU  A1402 (-4.2A)
None
 0.99A 1gmkA-4e9xA:
undetectable
1gmkB-4e9xA:
undetectable		 1gmkA-4e9xA:
4.50
1gmkB-4e9xA:
4.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 4 HIS A1057
CYH A1105
HIS A1112
MET A1118
 CU  A1401 (-3.1A)
CU  A1401 (-2.2A)
CU  A1401 (-3.1A)
CU  A1401 (-2.7A)
 0.40A 1oe1A-4e9xA:
25.3		 1oe1A-4e9xA:
27.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 5 HIS A1057
CYH A1105
HIS A1112
MET A1118
 CU  A1401 (-3.1A)
CU  A1401 (-2.2A)
CU  A1401 (-3.1A)
CU  A1401 (-2.7A)
 0.39A 1oe2A-4e9xA:
25.2		 1oe2A-4e9xA:
27.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 4 HIS A1057
CYH A1105
HIS A1112
MET A1118
 CU  A1401 (-3.1A)
CU  A1401 (-2.2A)
CU  A1401 (-3.1A)
CU  A1401 (-2.7A)
 0.43A 1oe3A-4e9xA:
25.3		 1oe3A-4e9xA:
27.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDS_B_SAMB9635_0
(PROTEIN RDMB)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		5 / 12 GLY A1262
GLY A1263
ASP A1253
PHE A1168
SER A1149
 None
 1.05A 1xdsB-4e9xA:
undetectable		 1xdsB-4e9xA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YDD_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		5 / 10 HIS A1106
HIS A1060
HIS A1104
VAL A1109
VAL A1113
 None
None
CU  A1402 ( 3.2A)
None
None
 1.31A 1yddA-4e9xA:
undetectable		 1yddA-4e9xA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQD_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 4 HIS A1057
CYH A1105
HIS A1112
MET A1118
 CU  A1401 (-3.1A)
CU  A1401 (-2.2A)
CU  A1401 (-3.1A)
CU  A1401 (-2.7A)
 0.52A 2fqdA-4e9xA:
23.4		 2fqdA-4e9xA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 4 HIS A1057
CYH A1105
HIS A1112
MET A1118
 CU  A1401 (-3.1A)
CU  A1401 (-2.2A)
CU  A1401 (-3.1A)
CU  A1401 (-2.7A)
 0.50A 2fqeA-4e9xA:
23.5		 2fqeA-4e9xA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 4 HIS A1057
CYH A1105
HIS A1112
MET A1118
 CU  A1401 (-3.1A)
CU  A1401 (-2.2A)
CU  A1401 (-3.1A)
CU  A1401 (-2.7A)
 0.47A 2fqfA-4e9xA:
23.4		 2fqfA-4e9xA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 4 HIS A1057
CYH A1105
HIS A1112
MET A1118
 CU  A1401 (-3.1A)
CU  A1401 (-2.2A)
CU  A1401 (-3.1A)
CU  A1401 (-2.7A)
 0.50A 2fqgA-4e9xA:
23.4		 2fqgA-4e9xA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GEH_A_NHYA300_1
(CARBONIC ANHYDRASE 2)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		5 / 8 HIS A1106
HIS A1060
HIS A1104
VAL A1109
VAL A1113
 None
None
CU  A1402 ( 3.2A)
None
None
 1.28A 2gehA-4e9xA:
undetectable		 2gehA-4e9xA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_A_SAMA500_0
(HYPOTHETICAL PROTEIN)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 7 VAL A1183
ALA A1243
PRO A1180
THR A1271
 None
 0.99A 2q6oA-4e9xA:
undetectable		 2q6oA-4e9xA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_1
(NON-STRUCTURAL
PROTEIN 5)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		3 / 3 SER A1232
HIS A1204
ASP A1209
 None
CU  A1404 ( 3.0A)
None
 0.61A 2wa2B-4e9xA:
undetectable		 2wa2B-4e9xA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1337_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 4 HIS A1057
CYH A1105
HIS A1112
MET A1118
 CU  A1401 (-3.1A)
CU  A1401 (-2.2A)
CU  A1401 (-3.1A)
CU  A1401 (-2.7A)
 0.37A 2xxgA-4e9xA:
25.4		 2xxgA-4e9xA:
27.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 5 HIS A1057
CYH A1105
HIS A1112
MET A1118
 CU  A1401 (-3.1A)
CU  A1401 (-2.2A)
CU  A1401 (-3.1A)
CU  A1401 (-2.7A)
 0.39A 2xxgC-4e9xA:
25.4		 2xxgC-4e9xA:
27.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_2
(ADENOSYLHOMOCYSTEINA
SE)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		3 / 3 THR A1137
GLU A1242
HIS A1208
 None
 0.82A 3g1uB-4e9xA:
undetectable		 3g1uB-4e9xA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 5 LYS A1016
SER A1149
LEU A1177
SER A1174
 None
 1.16A 3ijxH-4e9xA:
undetectable		 3ijxH-4e9xA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 4 LYS A1016
SER A1149
LEU A1177
SER A1174
 None
 1.00A 3ik6H-4e9xA:
undetectable		 3ik6H-4e9xA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_H_HFZH800_1
(GLUTAMATE RECEPTOR 2)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 5 LYS A1016
SER A1149
LEU A1177
SER A1174
 None
 1.00A 3iluH-4e9xA:
undetectable		 3iluH-4e9xA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4D_A_TPFA490_1
(STEROL 14-ALPHA
DEMETHYLASE)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 8 TYR A1155
ALA A1085
THR A1009
MET A1118
 None
None
None
CU  A1401 (-2.7A)
 0.90A 3l4dA-4e9xA:
undetectable		 3l4dA-4e9xA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA357_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		3 / 3 HIS A1252
HIS A1204
HIS A1206
 CU  A1403 ( 3.2A)
CU  A1404 ( 3.0A)
CU  A1403 (-3.1A)
 0.78A 3mihA-4e9xA:
undetectable		 3mihA-4e9xA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ML5_A_AZMA264_1
(CARBONIC ANHYDRASE 7)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		5 / 11 HIS A1106
HIS A1060
HIS A1104
VAL A1109
VAL A1113
 None
None
CU  A1402 ( 3.2A)
None
None
 1.32A 3ml5A-4e9xA:
undetectable		 3ml5A-4e9xA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_B_ACRB665_1
(ALPHA-GLUCOSIDASE)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 6 GLU A1041
ASP A1043
ASP A1044
LYS A1002
 None
 1.32A 3pocB-4e9xA:
undetectable		 3pocB-4e9xA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYE_B_YTZB902_1
(DIHYDROPTEROATE
SYNTHASE)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		3 / 3 PHE A1313
LYS A1173
SER A1169
 None
 1.13A 3tyeB-4e9xA:
undetectable		 3tyeB-4e9xA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		5 / 11 HIS A1106
HIS A1060
HIS A1104
VAL A1109
VAL A1113
 None
None
CU  A1402 ( 3.2A)
None
None
 1.33A 3v2jA-4e9xA:
undetectable		 3v2jA-4e9xA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		5 / 10 HIS A1106
HIS A1060
HIS A1104
VAL A1109
VAL A1113
 None
None
CU  A1402 ( 3.2A)
None
None
 1.30A 4coqA-4e9xA:
undetectable		 4coqA-4e9xA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		5 / 9 HIS A1106
HIS A1060
HIS A1104
VAL A1109
VAL A1113
 None
None
CU  A1402 ( 3.2A)
None
None
 1.29A 4coqB-4e9xA:
undetectable		 4coqB-4e9xA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1001_0
(BLUE COPPER OXIDASE
CUEO)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 4 HIS A1057
CYH A1105
HIS A1112
MET A1118
 CU  A1401 (-3.1A)
CU  A1401 (-2.2A)
CU  A1401 (-3.1A)
CU  A1401 (-2.7A)
 0.48A 4ef3A-4e9xA:
23.1		 4ef3A-4e9xA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP4_A_COCA706_1
(DOPAMINE TRANSPORTER)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		5 / 11 ASP A1096
VAL A1039
ASP A1125
GLY A1063
GLY A1099
 None
 1.19A 4xp4A-4e9xA:
undetectable		 4xp4A-4e9xA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_D_AZMD303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		5 / 11 HIS A1106
HIS A1060
HIS A1104
VAL A1109
VAL A1113
 None
None
CU  A1402 ( 3.2A)
None
None
 1.38A 4ygfD-4e9xA:
undetectable		 4ygfD-4e9xA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_H_AZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		5 / 9 HIS A1106
HIS A1060
HIS A1104
VAL A1109
VAL A1113
 None
None
CU  A1402 ( 3.2A)
None
None
 1.37A 4ygfH-4e9xA:
undetectable		 4ygfH-4e9xA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_C_MZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		5 / 11 HIS A1106
HIS A1060
HIS A1104
VAL A1109
VAL A1113
 None
None
CU  A1402 ( 3.2A)
None
None
 1.32A 4yhaC-4e9xA:
undetectable		 4yhaC-4e9xA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_G_MZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		5 / 12 HIS A1106
HIS A1060
HIS A1104
VAL A1109
VAL A1113
 None
None
CU  A1402 ( 3.2A)
None
None
 1.34A 4yhaG-4e9xA:
undetectable		 4yhaG-4e9xA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_1_BEZ1801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		3 / 3 LEU A1122
PHE A1194
ILE A1123
 None
 0.73A 5dzk1-4e9xA:
undetectable
5dzkF-4e9xA:
undetectable
5dzkM-4e9xA:
undetectable		 5dzk1-4e9xA:
5.56
5dzkF-4e9xA:
20.83
5dzkM-4e9xA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		5 / 10 HIS A1106
HIS A1060
HIS A1104
VAL A1109
VAL A1113
 None
None
CU  A1402 ( 3.2A)
None
None
 1.26A 5jn9B-4e9xA:
undetectable		 5jn9B-4e9xA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		5 / 10 HIS A1106
HIS A1060
HIS A1104
VAL A1109
VAL A1113
 None
None
CU  A1402 ( 3.2A)
None
None
 1.24A 5jn9D-4e9xA:
undetectable		 5jn9D-4e9xA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		5 / 11 HIS A1106
HIS A1060
HIS A1104
VAL A1109
VAL A1113
 None
None
CU  A1402 ( 3.2A)
None
None
 1.27A 5jncA-4e9xA:
undetectable		 5jncA-4e9xA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		5 / 10 HIS A1106
HIS A1060
HIS A1104
VAL A1109
VAL A1113
 None
None
CU  A1402 ( 3.2A)
None
None
 1.24A 5jncB-4e9xA:
undetectable		 5jncB-4e9xA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		5 / 10 HIS A1106
HIS A1060
HIS A1104
VAL A1109
VAL A1113
 None
None
CU  A1402 ( 3.2A)
None
None
 1.27A 5ku6B-4e9xA:
undetectable		 5ku6B-4e9xA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA502_0
(LACCASE 2)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 6 HIS A1060
HIS A1062
TRP A1102
HIS A1104
 None
CU  A1402 (-3.0A)
CU  A1402 (-4.2A)
CU  A1402 ( 3.2A)
 0.18A 5mejA-4e9xA:
27.1		 5mejA-4e9xA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA502_0
(LACCASE 2)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 6 HIS A1060
HIS A1062
TRP A1102
HIS A1104
 None
CU  A1402 (-3.0A)
CU  A1402 (-4.2A)
CU  A1402 ( 3.2A)
 0.18A 5mewA-4e9xA:
27.1		 5mewA-4e9xA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA502_0
(LACCASE 2)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 6 HIS A1060
HIS A1062
TRP A1102
HIS A1104
 None
CU  A1402 (-3.0A)
CU  A1402 (-4.2A)
CU  A1402 ( 3.2A)
 0.18A 5mhuA-4e9xA:
27.2		 5mhuA-4e9xA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA502_0
(LACCASE 2)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 6 HIS A1060
HIS A1062
TRP A1102
HIS A1104
 None
CU  A1402 (-3.0A)
CU  A1402 (-4.2A)
CU  A1402 ( 3.2A)
 0.18A 5mhvA-4e9xA:
27.1		 5mhvA-4e9xA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA602_0
(LACCASE 2)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 5 HIS A1060
HIS A1062
TRP A1102
HIS A1104
 None
CU  A1402 (-3.0A)
CU  A1402 (-4.2A)
CU  A1402 ( 3.2A)
 0.18A 5mhwA-4e9xA:
27.1		 5mhwA-4e9xA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA602_0
(LACCASE 2)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 5 HIS A1254
HIS A1204
HIS A1252
HIS A1206
 OXY  A1405 ( 3.8A)
CU  A1404 ( 3.0A)
CU  A1403 ( 3.2A)
CU  A1403 (-3.1A)
 0.85A 5mhwA-4e9xA:
27.1		 5mhwA-4e9xA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA602_0
(LACCASE 2)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 5 HIS A1060
HIS A1062
TRP A1102
HIS A1104
 None
CU  A1402 (-3.0A)
CU  A1402 (-4.2A)
CU  A1402 ( 3.2A)
 0.18A 5mhxA-4e9xA:
27.1		 5mhxA-4e9xA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA602_0
(LACCASE 2)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 5 HIS A1254
HIS A1204
HIS A1252
HIS A1206
 OXY  A1405 ( 3.8A)
CU  A1404 ( 3.0A)
CU  A1403 ( 3.2A)
CU  A1403 (-3.1A)
 0.85A 5mhxA-4e9xA:
27.1		 5mhxA-4e9xA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA602_0
(LACCASE 2)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 5 HIS A1060
HIS A1062
TRP A1102
HIS A1104
 None
CU  A1402 (-3.0A)
CU  A1402 (-4.2A)
CU  A1402 ( 3.2A)
 0.18A 5mhyA-4e9xA:
27.1		 5mhyA-4e9xA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA602_0
(LACCASE 2)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 5 HIS A1254
HIS A1204
HIS A1252
HIS A1206
 OXY  A1405 ( 3.8A)
CU  A1404 ( 3.0A)
CU  A1403 ( 3.2A)
CU  A1403 (-3.1A)
 0.85A 5mhyA-4e9xA:
27.1		 5mhyA-4e9xA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA602_0
(LACCASE 2)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 5 HIS A1060
HIS A1062
TRP A1102
HIS A1104
 None
CU  A1402 (-3.0A)
CU  A1402 (-4.2A)
CU  A1402 ( 3.2A)
 0.19A 5mhzA-4e9xA:
27.1		 5mhzA-4e9xA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA602_0
(LACCASE 2)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 5 HIS A1254
HIS A1204
HIS A1252
HIS A1206
 OXY  A1405 ( 3.8A)
CU  A1404 ( 3.0A)
CU  A1403 ( 3.2A)
CU  A1403 (-3.1A)
 0.85A 5mhzA-4e9xA:
27.1		 5mhzA-4e9xA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA602_0
(LACCASE 2)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 5 HIS A1060
HIS A1062
TRP A1102
HIS A1104
 None
CU  A1402 (-3.0A)
CU  A1402 (-4.2A)
CU  A1402 ( 3.2A)
 0.19A 5mi1A-4e9xA:
27.1		 5mi1A-4e9xA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA602_0
(LACCASE 2)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 5 HIS A1254
HIS A1204
HIS A1252
HIS A1206
 OXY  A1405 ( 3.8A)
CU  A1404 ( 3.0A)
CU  A1403 ( 3.2A)
CU  A1403 (-3.1A)
 0.85A 5mi1A-4e9xA:
27.1		 5mi1A-4e9xA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA602_0
(LACCASE 2)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 5 HIS A1060
HIS A1062
TRP A1102
HIS A1104
 None
CU  A1402 (-3.0A)
CU  A1402 (-4.2A)
CU  A1402 ( 3.2A)
 0.18A 5mi2A-4e9xA:
27.0		 5mi2A-4e9xA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA602_0
(LACCASE 2)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 5 HIS A1254
HIS A1204
HIS A1252
HIS A1206
 OXY  A1405 ( 3.8A)
CU  A1404 ( 3.0A)
CU  A1403 ( 3.2A)
CU  A1403 (-3.1A)
 0.85A 5mi2A-4e9xA:
27.0		 5mi2A-4e9xA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA602_0
(LACCASE 2)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 5 HIS A1060
HIS A1062
TRP A1102
HIS A1104
 None
CU  A1402 (-3.0A)
CU  A1402 (-4.2A)
CU  A1402 ( 3.2A)
 0.19A 5miaA-4e9xA:
27.1		 5miaA-4e9xA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA602_0
(LACCASE 2)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 5 HIS A1254
HIS A1204
HIS A1252
HIS A1206
 OXY  A1405 ( 3.8A)
CU  A1404 ( 3.0A)
CU  A1403 ( 3.2A)
CU  A1403 (-3.1A)
 0.85A 5miaA-4e9xA:
27.1		 5miaA-4e9xA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA602_0
(LACCASE 2)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 5 HIS A1060
HIS A1062
TRP A1102
HIS A1104
 None
CU  A1402 (-3.0A)
CU  A1402 (-4.2A)
CU  A1402 ( 3.2A)
 0.19A 5mibA-4e9xA:
27.1		 5mibA-4e9xA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA602_0
(LACCASE 2)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 5 HIS A1254
HIS A1204
HIS A1252
HIS A1206
 OXY  A1405 ( 3.8A)
CU  A1404 ( 3.0A)
CU  A1403 ( 3.2A)
CU  A1403 (-3.1A)
 0.85A 5mibA-4e9xA:
27.1		 5mibA-4e9xA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA602_0
(LACCASE 2)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 5 HIS A1060
HIS A1062
TRP A1102
HIS A1104
 None
CU  A1402 (-3.0A)
CU  A1402 (-4.2A)
CU  A1402 ( 3.2A)
 0.19A 5micA-4e9xA:
27.1		 5micA-4e9xA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA602_0
(LACCASE 2)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 5 HIS A1254
HIS A1204
HIS A1252
HIS A1206
 OXY  A1405 ( 3.8A)
CU  A1404 ( 3.0A)
CU  A1403 ( 3.2A)
CU  A1403 (-3.1A)
 0.86A 5micA-4e9xA:
27.1		 5micA-4e9xA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA602_0
(LACCASE 2)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 5 HIS A1060
HIS A1062
TRP A1102
HIS A1104
 None
CU  A1402 (-3.0A)
CU  A1402 (-4.2A)
CU  A1402 ( 3.2A)
 0.19A 5midA-4e9xA:
27.1		 5midA-4e9xA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA602_0
(LACCASE 2)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 5 HIS A1254
HIS A1204
HIS A1252
HIS A1206
 OXY  A1405 ( 3.8A)
CU  A1404 ( 3.0A)
CU  A1403 ( 3.2A)
CU  A1403 (-3.1A)
 0.85A 5midA-4e9xA:
27.1		 5midA-4e9xA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA602_0
(LACCASE 2)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 5 HIS A1060
HIS A1062
TRP A1102
HIS A1104
 None
CU  A1402 (-3.0A)
CU  A1402 (-4.2A)
CU  A1402 ( 3.2A)
 0.19A 5mieA-4e9xA:
27.1		 5mieA-4e9xA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA602_0
(LACCASE 2)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 5 HIS A1254
HIS A1204
HIS A1252
HIS A1206
 OXY  A1405 ( 3.8A)
CU  A1404 ( 3.0A)
CU  A1403 ( 3.2A)
CU  A1403 (-3.1A)
 0.86A 5mieA-4e9xA:
27.1		 5mieA-4e9xA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA602_0
(LACCASE 2)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 5 HIS A1060
HIS A1062
TRP A1102
HIS A1104
 None
CU  A1402 (-3.0A)
CU  A1402 (-4.2A)
CU  A1402 ( 3.2A)
 0.19A 5migA-4e9xA:
27.1		 5migA-4e9xA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA602_0
(LACCASE 2)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 5 HIS A1254
HIS A1204
HIS A1252
HIS A1206
 OXY  A1405 ( 3.8A)
CU  A1404 ( 3.0A)
CU  A1403 ( 3.2A)
CU  A1403 (-3.1A)
 0.85A 5migA-4e9xA:
27.1		 5migA-4e9xA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_E_EZLE303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		5 / 9 HIS A1106
HIS A1060
HIS A1104
VAL A1109
VAL A1113
 None
None
CU  A1402 ( 3.2A)
None
None
 1.29A 5tt3E-4e9xA:
undetectable		 5tt3E-4e9xA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_G_EZLG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		5 / 9 HIS A1106
HIS A1060
HIS A1104
VAL A1109
VAL A1113
 None
None
CU  A1402 ( 3.2A)
None
None
 1.33A 5tt3G-4e9xA:
undetectable		 5tt3G-4e9xA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		 4e9x MULTICOPPER OXIDASE
(uncultured
bacterium) 		4 / 7 ASN A1163
ASN A1110
GLU A1111
ARG A1116
 None
 1.16A 6b8kA-4e9xA:
undetectable		 6b8kA-4e9xA:
14.05