SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4eae'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBM_A_CAMA517_0
(CYTOCHROME P450-CAM)		 4eae LMO1068 PROTEIN
(Listeria
monocytogenes) 		4 / 8 THR A 243
VAL A 152
VAL A 159
ILE A 117
 None
 0.93A 2qbmA-4eaeA:
undetectable		 2qbmA-4eaeA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		 4eae LMO1068 PROTEIN
(Listeria
monocytogenes) 		4 / 8 TYR A 192
ILE A 182
LEU A 210
LEU A 240
 None
 0.81A 2w98B-4eaeA:
undetectable		 2w98B-4eaeA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B301_1
(THIOPURINE
S-METHYLTRANSFERASE)		 4eae LMO1068 PROTEIN
(Listeria
monocytogenes) 		4 / 8 GLY A 173
VAL A 152
LEU A 118
PRO A 155
 None
 0.81A 3bgdB-4eaeA:
undetectable		 3bgdB-4eaeA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_F_SAMF300_0
(PUTATIVE RRNA
METHYLASE)		 4eae LMO1068 PROTEIN
(Listeria
monocytogenes) 		5 / 12 GLY A 222
ASN A 229
ASP A 226
GLY A 217
HIS A 219
 None
 1.18A 3eeyF-4eaeA:
undetectable		 3eeyF-4eaeA:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 4eae LMO1068 PROTEIN
(Listeria
monocytogenes) 		3 / 3 LYS A 193
ASP A 195
ARG A 265
 None
MLT  A 301 ( 4.9A)
None
 1.10A 5jwaA-4eaeA:
undetectable
5jwaH-4eaeA:
undetectable		 5jwaA-4eaeA:
19.02
5jwaH-4eaeA:
19.02