SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4eah'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4eah FORMIN-LIKE PROTEIN
3
(Mus
musculus) 		3 / 3 VAL A 816
ALA A 813
HIS A 810
 None
 0.79A 1q23L-4eahA:
undetectable		 1q23L-4eahA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_D_H4BD1290_1
(PTERIDINE REDUCTASE
1)		 4eah FORMIN-LIKE PROTEIN
3
(Mus
musculus) 		4 / 8 PHE A 914
LEU A 790
LEU A 763
LEU A 830
 None
 1.02A 2bfpD-4eahA:
undetectable		 2bfpD-4eahA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2002_1
(SERUM ALBUMIN)		 4eah FORMIN-LIKE PROTEIN
3
(Mus
musculus) 		4 / 8 ALA A 752
ALA A 836
LYS A 835
GLU A 834
 None
 0.80A 2bxgA-4eahA:
3.7		 2bxgA-4eahA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O02_B_JN3B1_1
(CELL INVASION
PROTEIN SIPD)		 4eah FORMIN-LIKE PROTEIN
3
(Mus
musculus) 		5 / 10 ILE A 750
ALA A 888
LEU A 841
LEU A 845
VAL A 848
 None
 1.01A 3o02A-4eahA:
undetectable
3o02B-4eahA:
undetectable		 3o02A-4eahA:
22.82
3o02B-4eahA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_0
(PUTATIVE REGULATORY
PROTEIN)		 4eah FORMIN-LIKE PROTEIN
3
(Mus
musculus) 		5 / 12 LEU A 809
TYR A 925
ILE A 812
VAL A 757
PHE A 826
 None
 1.23A 3vw1D-4eahA:
undetectable		 3vw1D-4eahA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA604_0
(SERUM ALBUMIN)		 4eah FORMIN-LIKE PROTEIN
3
(Mus
musculus) 		4 / 8 ALA A 752
ALA A 836
LYS A 835
GLU A 834
 None
 0.74A 6mdqA-4eahA:
2.2		 6mdqA-4eahA:
10.95