SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4eb5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q8J_B_C2FB802_0
(5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		5 / 12 GLU A 150
GLY A 124
ILE A 304
GLY A 318
SER A 329
 None
 1.16A 1q8jB-4eb5A:
undetectable		 1q8jB-4eb5A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA-1)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		5 / 12 ILE A  78
ILE A  77
ALA A  81
LEU A 209
ILE A 211
 GOL  A 403 ( 4.7A)
None
None
None
None
 1.08A 1xzxX-4eb5A:
undetectable		 1xzxX-4eb5A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_A_SAMA500_0
(HYPOTHETICAL PROTEIN)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		4 / 7 VAL A  93
ALA A 105
PHE A 130
PRO A 119
 None
 0.93A 2q6oA-4eb5A:
undetectable		 2q6oA-4eb5A:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_B_BEZB143_0
(PUTATIVE REDOX
PROTEIN)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		4 / 6 ARG A  15
ALA A 246
ARG A 352
PRO A  11
 None
 1.42A 2ql8A-4eb5A:
undetectable
2ql8B-4eb5A:
undetectable		 2ql8A-4eb5A:
16.75
2ql8B-4eb5A:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9H_A_TOPA1160_1
(DIHYDROFOLATE
REDUCTASE)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		5 / 10 LEU A 273
LEU A 362
LEU A 346
VAL A 294
ILE A 370
 None
 1.11A 2w9hA-4eb5A:
undetectable		 2w9hA-4eb5A:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_A_DIFA1_1
(TRANSTHYRETIN)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		4 / 6 LEU A 337
ALA A 334
LEU A 332
SER A 329
 None
 1.03A 3cfqA-4eb5A:
undetectable		 3cfqA-4eb5A:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6P_B_TA1B502_1
(TUBULIN BETA CHAIN)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		5 / 12 VAL A 101
SER A 143
ARG A 231
GLY A  79
LEU A 217
 None
 1.08A 3j6pB-4eb5A:
undetectable		 3j6pB-4eb5A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_K_DHIK3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		3 / 3 LEU A 193
TRP A 210
GLY A  59
 None
 0.81A 3l35B-4eb5A:
undetectable
3l35K-4eb5A:
undetectable		 3l35B-4eb5A:
8.24
3l35K-4eb5A:
2.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_1
(ADENOSINE KINASE)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		5 / 12 ASN A 281
ILE A 151
GLY A 152
LEU A 337
THR A   7
 None
 1.00A 3uboB-4eb5A:
3.3		 3uboB-4eb5A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_A_ADNA901_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		5 / 9 ALA A  81
GLY A  79
LEU A  75
ASN A  74
ILE A 211
 None
 1.38A 3wdmA-4eb5A:
3.0		 3wdmA-4eb5A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		4 / 5 PHE A 296
LEU A 348
ILE A 370
VAL A 369
 None
 0.83A 3wrkA-4eb5A:
undetectable		 3wrkA-4eb5A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_C_PXLC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		4 / 8 GLY A  61
GLY A  59
VAL A  63
VAL A 185
 None
 0.88A 4c5nC-4eb5A:
2.7		 4c5nC-4eb5A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_A_ADNA500_1
(SUGAR KINASE PROTEIN)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		5 / 12 ASN A 281
ILE A 151
GLY A 152
LEU A 337
THR A   7
 None
 1.02A 4e3aA-4eb5A:
3.3		 4e3aA-4eb5A:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_B_SAMB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		5 / 12 ILE A 200
GLY A 242
GLY A 202
ILE A 240
ARG A  15
 None
 1.09A 4iv0B-4eb5A:
undetectable		 4iv0B-4eb5A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_B_ADNB500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		5 / 12 ASN A 281
ILE A 151
GLY A 152
LEU A 337
THR A   7
 None
 0.99A 4jkuB-4eb5A:
2.4		 4jkuB-4eb5A:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_A_ADNA401_1
(SUGAR KINASE)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		5 / 12 ASN A 281
ILE A 151
GLY A 152
LEU A 337
THR A   7
 None
 0.98A 4k8pA-4eb5A:
2.4		 4k8pA-4eb5A:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_B_ADNB401_1
(SUGAR KINASE)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		5 / 12 ASN A 281
ILE A 151
GLY A 152
LEU A 337
THR A   7
 None
 0.98A 4k8pB-4eb5A:
2.3		 4k8pB-4eb5A:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_A_ADNA401_1
(SUGAR KINASE)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		5 / 12 ASN A 281
ILE A 151
GLY A 152
LEU A 337
THR A   7
 None
 0.97A 4k8tA-4eb5A:
3.3		 4k8tA-4eb5A:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_B_ADNB401_1
(SUGAR KINASE)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		5 / 12 ASN A 281
ILE A 151
GLY A 152
LEU A 337
THR A   7
 None
 1.00A 4k8tB-4eb5A:
3.3		 4k8tB-4eb5A:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_A_ADNA401_1
(SUGAR KINASE)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		5 / 12 ASN A 281
ILE A 151
GLY A 152
LEU A 337
THR A   7
 None
 1.00A 4k93A-4eb5A:
3.6		 4k93A-4eb5A:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_B_ADNB402_1
(SUGAR KINASE)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		5 / 12 ASN A 281
ILE A 151
GLY A 152
LEU A 337
THR A   7
 None
 0.99A 4k93B-4eb5A:
3.4		 4k93B-4eb5A:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_A_ADNA401_1
(SUGAR KINASE)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		5 / 12 ASN A 281
ILE A 151
GLY A 152
LEU A 337
THR A   7
 None
 0.99A 4k9cA-4eb5A:
3.3		 4k9cA-4eb5A:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_B_ADNB401_1
(SUGAR KINASE)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		5 / 12 ASN A 281
ILE A 151
GLY A 152
LEU A 337
THR A   7
 None
 0.99A 4k9cB-4eb5A:
2.5		 4k9cB-4eb5A:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_A_ADNA401_1
(SUGAR KINASE)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		5 / 12 ASN A 281
ILE A 151
GLY A 152
LEU A 337
THR A   7
 None
 0.99A 4k9iA-4eb5A:
3.3		 4k9iA-4eb5A:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_B_ADNB401_1
(SUGAR KINASE)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		5 / 12 ASN A 281
ILE A 151
GLY A 152
LEU A 337
THR A   7
 None
 1.00A 4k9iB-4eb5A:
3.4		 4k9iB-4eb5A:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		5 / 12 ASN A 281
ILE A 151
GLY A 152
LEU A 337
THR A   7
 None
 0.99A 4kadA-4eb5A:
3.6		 4kadA-4eb5A:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		5 / 12 ASN A 281
ILE A 151
GLY A 152
LEU A 337
THR A   7
 None
 0.98A 4kadB-4eb5A:
3.5		 4kadB-4eb5A:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOT_A_CE3A205_1
(UNCHARACTERIZED
PROTEIN)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		5 / 12 ARG A 287
GLY A 152
ASN A 291
ARG A 295
LEU A 337
 None
 1.39A 4kotA-4eb5A:
undetectable		 4kotA-4eb5A:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		5 / 12 ASN A 281
ILE A 151
GLY A 152
LEU A 337
THR A   7
 None
 0.98A 4lbxA-4eb5A:
2.4		 4lbxA-4eb5A:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		5 / 12 ASN A 281
ILE A 151
GLY A 152
LEU A 337
THR A   7
 None
 0.99A 4lbxB-4eb5A:
3.0		 4lbxB-4eb5A:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		5 / 12 ASN A 281
ILE A 151
GLY A 152
LEU A 337
THR A   7
 None
 0.98A 4lc4A-4eb5A:
2.3		 4lc4A-4eb5A:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		5 / 12 ASN A 281
ILE A 151
GLY A 152
LEU A 337
THR A   7
 None
 0.98A 4lc4B-4eb5A:
3.3		 4lc4B-4eb5A:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MV7_A_PPFA501_1
(BIOTIN CARBOXYLASE)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		4 / 7 ASN A 148
GLN A 145
VAL A 144
GLU A  97
 None
 1.29A 4mv7A-4eb5A:
2.5		 4mv7A-4eb5A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		5 / 12 ILE A 200
GLY A 242
GLY A 202
ILE A 240
ARG A  15
 None
 1.09A 4mwzA-4eb5A:
2.3		 4mwzA-4eb5A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_1
(ADENOSINE KINASE)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		5 / 12 LEU A 308
ASN A 290
ALA A 315
LEU A 346
GLY A 351
 None
 0.91A 4n09C-4eb5A:
undetectable		 4n09C-4eb5A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_2_BEZ2801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		4 / 4 LEU A 273
ARG A 374
ILE A 275
ILE A 370
 None
 1.19A 5dzk2-4eb5A:
undetectable
5dzkM-4eb5A:
undetectable
5dzkN-4eb5A:
undetectable		 5dzk2-4eb5A:
0.58
5dzkM-4eb5A:
19.74
5dzkN-4eb5A:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_V_BEZV801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		4 / 4 ILE A 275
ILE A 370
ARG A 374
LEU A 273
 None
 1.15A 5dzkh-4eb5A:
undetectable
5dzkn-4eb5A:
undetectable
5dzkv-4eb5A:
undetectable		 5dzkh-4eb5A:
19.74
5dzkn-4eb5A:
19.74
5dzkv-4eb5A:
0.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I6X_A_8PRA705_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		5 / 10 ALA A 208
ILE A 195
GLY A 202
PHE A 243
GLY A  68
 None
None
None
None
PLP  A 401 ( 4.6A)
 1.22A 5i6xA-4eb5A:
undetectable		 5i6xA-4eb5A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_1
(ADENOSINE KINASE)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		5 / 12 LEU A 308
ASN A 290
ALA A 315
LEU A 346
GLY A 351
 None
 0.92A 5kb5A-4eb5A:
undetectable		 5kb5A-4eb5A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_B_PFLB510_1
(PROTON-GATED ION
CHANNEL)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		4 / 6 ILE A  91
ALA A 105
LEU A 108
ILE A  78
 None
None
None
GOL  A 403 ( 4.7A)
 0.79A 5mvmB-4eb5A:
undetectable
5mvmC-4eb5A:
undetectable		 5mvmB-4eb5A:
14.68
5mvmC-4eb5A:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGC_B_TA1B601_1
(TUBULIN BETA CHAIN)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		5 / 12 VAL A 101
SER A 143
ARG A 231
GLY A  79
LEU A 217
 None
 1.11A 5ogcB-4eb5A:
undetectable		 5ogcB-4eb5A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYF_B_TA1B502_1
(TUBULIN BETA CHAIN)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		5 / 12 VAL A 183
ASP A 184
HIS A 146
ALA A 174
LEU A 170
 GOL  A 402 (-3.8A)
None
None
None
None
 1.32A 5syfB-4eb5A:
undetectable		 5syfB-4eb5A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUI_B_CTCB405_0
(TETRACYCLINE
DESTRUCTASE TET(50))		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		5 / 12 GLY A 242
THR A 250
GLY A 179
GLY A 207
VAL A  63
 None
None
GOL  A 402 (-3.3A)
None
None
 0.86A 5tuiB-4eb5A:
undetectable		 5tuiB-4eb5A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_B_SUEB1202_0
(NS3 PROTEASE)		 4eb5 PROBABLE CYSTEINE
DESULFURASE 2
(Archaeoglobus
fulgidus) 		5 / 12 GLY A 189
VAL A 142
ARG A  83
GLY A  60
ALA A 215
 None
 1.21A 6c2mB-4eb5A:
undetectable		 6c2mB-4eb5A:
13.40