SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ebj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4ebj AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Pseudomonas
aeruginosa)
5 / 11 GLY A  90
ALA A 177
THR A  93
HIS A 118
ALA A 174
None
None
None
None
SO4  A 303 (-3.6A)
1.10A 1gtnM-4ebjA:
undetectable
1gtnN-4ebjA:
undetectable
1gtnM-4ebjA:
14.71
1gtnN-4ebjA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4ebj AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Pseudomonas
aeruginosa)
5 / 10 GLY A  90
ALA A 177
THR A  93
HIS A 118
ALA A 174
None
None
None
None
SO4  A 303 (-3.6A)
1.13A 1gtnO-4ebjA:
undetectable
1gtnP-4ebjA:
undetectable
1gtnO-4ebjA:
14.71
1gtnP-4ebjA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4ebj AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Pseudomonas
aeruginosa)
5 / 10 GLY A  90
ALA A 177
THR A  93
HIS A 118
ALA A 174
None
None
None
None
SO4  A 303 (-3.6A)
1.11A 1gtnU-4ebjA:
undetectable
1gtnV-4ebjA:
undetectable
1gtnU-4ebjA:
14.71
1gtnV-4ebjA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_1
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)
4ebj AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Pseudomonas
aeruginosa)
4 / 4 ILE A 165
LEU A 162
VAL A 158
ALA A 151
None
0.79A 1mz9A-4ebjA:
undetectable
1mz9A-4ebjA:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)
4ebj AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Pseudomonas
aeruginosa)
4 / 5 ILE A 165
LEU A 162
VAL A 158
ALA A 151
None
0.81A 1mz9C-4ebjA:
undetectable
1mz9C-4ebjA:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_T_TRPT81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4ebj AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Pseudomonas
aeruginosa)
5 / 10 GLY A  90
ALA A 177
THR A  93
HIS A 118
ALA A 174
None
None
None
None
SO4  A 303 (-3.6A)
1.11A 1utdT-4ebjA:
undetectable
1utdU-4ebjA:
undetectable
1utdT-4ebjA:
14.71
1utdU-4ebjA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)
4ebj AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Pseudomonas
aeruginosa)
3 / 3 TRP A  56
GLU A  15
TYR A  16
None
0.76A 2a3aA-4ebjA:
undetectable
2a3aA-4ebjA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6V_B_SAMB465_0
(RRNA METHYLASE)
4ebj AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Pseudomonas
aeruginosa)
5 / 12 GLY A 220
ARG A 186
PRO A 123
PRO A 226
LEU A 231
None
1.10A 3m6vB-4ebjA:
undetectable
3m6vB-4ebjA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDA_A_RLTA403_1
(MARINER MOS1
TRANSPOSASE)
4ebj AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Pseudomonas
aeruginosa)
4 / 6 ASP A  38
ASP A  40
ALA A  70
TYR A  53
None
1.04A 4mdaA-4ebjA:
undetectable
4mdaA-4ebjA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDB_A_RLTA401_1
(MARINER MOS1
TRANSPOSASE)
4ebj AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Pseudomonas
aeruginosa)
4 / 6 ASP A  38
ASP A  40
ALA A  70
TYR A  53
None
1.03A 4mdbA-4ebjA:
undetectable
4mdbA-4ebjA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)
4ebj AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Pseudomonas
aeruginosa)
3 / 3 PRO A  92
LEU A  91
GLN A 176
None
0.70A 4pevB-4ebjA:
undetectable
4pevB-4ebjA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_A_3CJA607_1
(LACTOPEROXIDASE)
4ebj AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Pseudomonas
aeruginosa)
3 / 3 GLN A 176
HIS A 173
ARG A  30
None
SO4  A 303 (-3.9A)
None
1.13A 4qyqA-4ebjA:
undetectable
4qyqA-4ebjA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_B_3CJB607_1
(LACTOPEROXIDASE)
4ebj AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Pseudomonas
aeruginosa)
3 / 3 GLN A 176
HIS A 173
ARG A  30
None
SO4  A 303 (-3.9A)
None
1.12A 4qyqB-4ebjA:
undetectable
4qyqB-4ebjA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4ebj AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Pseudomonas
aeruginosa)
5 / 10 ALA A 174
GLY A  90
ALA A 177
THR A  93
HIS A 118
SO4  A 303 (-3.6A)
None
None
None
None
1.17A 5eeuF-4ebjA:
undetectable
5eeuG-4ebjA:
undetectable
5eeuF-4ebjA:
14.71
5eeuG-4ebjA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4ebj AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Pseudomonas
aeruginosa)
5 / 12 ALA A 174
GLY A  90
ALA A 177
THR A  93
HIS A 118
SO4  A 303 (-3.6A)
None
None
None
None
1.10A 5eeuI-4ebjA:
undetectable
5eeuJ-4ebjA:
undetectable
5eeuI-4ebjA:
14.71
5eeuJ-4ebjA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4ebj AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Pseudomonas
aeruginosa)
5 / 10 GLY A  90
ALA A 177
THR A  93
HIS A 118
ALA A 174
None
None
None
None
SO4  A 303 (-3.6A)
1.12A 5eeuO-4ebjA:
undetectable
5eeuP-4ebjA:
undetectable
5eeuO-4ebjA:
14.71
5eeuP-4ebjA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4ebj AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Pseudomonas
aeruginosa)
5 / 10 GLY A  90
ALA A 177
THR A  93
HIS A 118
ALA A 174
None
None
None
None
SO4  A 303 (-3.6A)
1.15A 5eeuQ-4ebjA:
undetectable
5eeuR-4ebjA:
undetectable
5eeuQ-4ebjA:
14.71
5eeuR-4ebjA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4ebj AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Pseudomonas
aeruginosa)
5 / 10 ALA A 174
GLY A  90
ALA A 177
THR A  93
HIS A 118
SO4  A 303 (-3.6A)
None
None
None
None
1.16A 5eevF-4ebjA:
undetectable
5eevG-4ebjA:
undetectable
5eevF-4ebjA:
14.71
5eevG-4ebjA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4ebj AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Pseudomonas
aeruginosa)
5 / 12 ALA A 174
GLY A  90
ALA A 177
THR A  93
HIS A 118
SO4  A 303 (-3.6A)
None
None
None
None
1.10A 5eevI-4ebjA:
undetectable
5eevJ-4ebjA:
undetectable
5eevI-4ebjA:
14.71
5eevJ-4ebjA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4ebj AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Pseudomonas
aeruginosa)
5 / 10 GLY A  90
ALA A 177
THR A  93
HIS A 118
ALA A 174
None
None
None
None
SO4  A 303 (-3.6A)
1.12A 5eevO-4ebjA:
undetectable
5eevP-4ebjA:
undetectable
5eevO-4ebjA:
14.71
5eevP-4ebjA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4ebj AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Pseudomonas
aeruginosa)
5 / 10 GLY A  90
ALA A 177
THR A  93
HIS A 118
ALA A 174
None
None
None
None
SO4  A 303 (-3.6A)
1.14A 5eevQ-4ebjA:
undetectable
5eevR-4ebjA:
undetectable
5eevQ-4ebjA:
14.71
5eevR-4ebjA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4ebj AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Pseudomonas
aeruginosa)
5 / 10 ALA A 174
GLY A  90
ALA A 177
THR A  93
HIS A 118
SO4  A 303 (-3.6A)
None
None
None
None
1.16A 5eewF-4ebjA:
undetectable
5eewG-4ebjA:
undetectable
5eewF-4ebjA:
14.71
5eewG-4ebjA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4ebj AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Pseudomonas
aeruginosa)
5 / 12 ALA A 174
GLY A  90
ALA A 177
THR A  93
HIS A 118
SO4  A 303 (-3.6A)
None
None
None
None
1.10A 5eewI-4ebjA:
undetectable
5eewJ-4ebjA:
undetectable
5eewI-4ebjA:
14.71
5eewJ-4ebjA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4ebj AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Pseudomonas
aeruginosa)
5 / 10 GLY A  90
ALA A 177
THR A  93
HIS A 118
ALA A 174
None
None
None
None
SO4  A 303 (-3.6A)
1.12A 5eewO-4ebjA:
undetectable
5eewP-4ebjA:
undetectable
5eewO-4ebjA:
14.71
5eewP-4ebjA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4ebj AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Pseudomonas
aeruginosa)
5 / 10 GLY A  90
ALA A 177
THR A  93
HIS A 118
ALA A 174
None
None
None
None
SO4  A 303 (-3.6A)
1.14A 5eewQ-4ebjA:
undetectable
5eewR-4ebjA:
undetectable
5eewQ-4ebjA:
14.71
5eewR-4ebjA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4ebj AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Pseudomonas
aeruginosa)
5 / 10 ALA A 174
GLY A  90
ALA A 177
THR A  93
HIS A 118
SO4  A 303 (-3.6A)
None
None
None
None
1.16A 5eexF-4ebjA:
undetectable
5eexG-4ebjA:
undetectable
5eexF-4ebjA:
14.71
5eexG-4ebjA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4ebj AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Pseudomonas
aeruginosa)
5 / 10 GLY A  90
ALA A 177
THR A  93
HIS A 118
ALA A 174
None
None
None
None
SO4  A 303 (-3.6A)
1.12A 5eexO-4ebjA:
undetectable
5eexP-4ebjA:
undetectable
5eexO-4ebjA:
14.71
5eexP-4ebjA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4ebj AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Pseudomonas
aeruginosa)
5 / 10 ALA A 174
GLY A  90
ALA A 177
THR A  93
HIS A 118
SO4  A 303 (-3.6A)
None
None
None
None
1.16A 5eeyF-4ebjA:
undetectable
5eeyG-4ebjA:
undetectable
5eeyF-4ebjA:
14.71
5eeyG-4ebjA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4ebj AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Pseudomonas
aeruginosa)
5 / 10 GLY A  90
ALA A 177
THR A  93
HIS A 118
ALA A 174
None
None
None
None
SO4  A 303 (-3.6A)
1.12A 5eeyO-4ebjA:
undetectable
5eeyP-4ebjA:
undetectable
5eeyO-4ebjA:
14.71
5eeyP-4ebjA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4ebj AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Pseudomonas
aeruginosa)
5 / 10 ALA A 174
GLY A  90
ALA A 177
THR A  93
HIS A 118
SO4  A 303 (-3.6A)
None
None
None
None
1.16A 5eezF-4ebjA:
undetectable
5eezG-4ebjA:
undetectable
5eezF-4ebjA:
14.71
5eezG-4ebjA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4ebj AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Pseudomonas
aeruginosa)
5 / 10 GLY A  90
ALA A 177
THR A  93
HIS A 118
ALA A 174
None
None
None
None
SO4  A 303 (-3.6A)
1.12A 5eezO-4ebjA:
undetectable
5eezP-4ebjA:
undetectable
5eezO-4ebjA:
14.71
5eezP-4ebjA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4ebj AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Pseudomonas
aeruginosa)
5 / 10 ALA A 174
GLY A  90
ALA A 177
THR A  93
HIS A 118
SO4  A 303 (-3.6A)
None
None
None
None
1.16A 5ef0F-4ebjA:
undetectable
5ef0G-4ebjA:
undetectable
5ef0F-4ebjA:
14.71
5ef0G-4ebjA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4ebj AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Pseudomonas
aeruginosa)
5 / 10 GLY A  90
ALA A 177
THR A  93
HIS A 118
ALA A 174
None
None
None
None
SO4  A 303 (-3.6A)
1.11A 5ef0O-4ebjA:
undetectable
5ef0P-4ebjA:
undetectable
5ef0O-4ebjA:
14.71
5ef0P-4ebjA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4ebj AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Pseudomonas
aeruginosa)
5 / 10 ALA A 174
GLY A  90
ALA A 177
THR A  93
HIS A 118
SO4  A 303 (-3.6A)
None
None
None
None
1.16A 5ef1F-4ebjA:
undetectable
5ef1G-4ebjA:
undetectable
5ef1F-4ebjA:
14.71
5ef1G-4ebjA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4ebj AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Pseudomonas
aeruginosa)
5 / 10 GLY A  90
ALA A 177
THR A  93
HIS A 118
ALA A 174
None
None
None
None
SO4  A 303 (-3.6A)
1.11A 5ef1O-4ebjA:
undetectable
5ef1P-4ebjA:
undetectable
5ef1O-4ebjA:
14.71
5ef1P-4ebjA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4ebj AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Pseudomonas
aeruginosa)
5 / 10 ALA A 174
GLY A  90
ALA A 177
THR A  93
HIS A 118
SO4  A 303 (-3.6A)
None
None
None
None
1.16A 5ef2F-4ebjA:
undetectable
5ef2G-4ebjA:
undetectable
5ef2F-4ebjA:
14.71
5ef2G-4ebjA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4ebj AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Pseudomonas
aeruginosa)
5 / 10 GLY A  90
ALA A 177
THR A  93
HIS A 118
ALA A 174
None
None
None
None
SO4  A 303 (-3.6A)
1.11A 5ef2O-4ebjA:
undetectable
5ef2P-4ebjA:
undetectable
5ef2O-4ebjA:
14.71
5ef2P-4ebjA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4ebj AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Pseudomonas
aeruginosa)
5 / 10 ALA A 174
GLY A  90
ALA A 177
THR A  93
HIS A 118
SO4  A 303 (-3.6A)
None
None
None
None
1.16A 5ef3F-4ebjA:
undetectable
5ef3G-4ebjA:
undetectable
5ef3F-4ebjA:
14.71
5ef3G-4ebjA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4ebj AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Pseudomonas
aeruginosa)
5 / 10 GLY A  90
ALA A 177
THR A  93
HIS A 118
ALA A 174
None
None
None
None
SO4  A 303 (-3.6A)
1.12A 5ef3O-4ebjA:
undetectable
5ef3P-4ebjA:
undetectable
5ef3O-4ebjA:
14.71
5ef3P-4ebjA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_A_PFLA511_1
(PROTON-GATED ION
CHANNEL)
4ebj AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Pseudomonas
aeruginosa)
4 / 8 ILE A 139
ALA A 207
ALA A 214
GLU A 215
None
0.67A 5mvmA-4ebjA:
2.2
5mvmB-4ebjA:
undetectable
5mvmA-4ebjA:
14.45
5mvmB-4ebjA:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WM2_A_ACTA605_0
(SALICYLATE-AMP
LIGASE)
4ebj AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Pseudomonas
aeruginosa)
3 / 3 THR A 197
THR A 210
ARG A 205
None
1.05A 5wm2A-4ebjA:
2.3
5wm2A-4ebjA:
20.07