SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ebr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ebr UBIQUITIN-LIKE-CONJU
GATING ENZYME ATG10
(Saccharomyces
cerevisiae) 		4 / 7 LYS A  35
LEU A  11
GLN A  12
LEU A  67
 None
 1.03A 2eijP-4ebrA:
undetectable
2eijW-4ebrA:
undetectable		 2eijP-4ebrA:
20.88
2eijW-4ebrA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LBD_A_REAA500_1
(RETINOIC ACID
RECEPTOR GAMMA)		 4ebr UBIQUITIN-LIKE-CONJU
GATING ENZYME ATG10
(Saccharomyces
cerevisiae) 		5 / 12 PHE A  20
LEU A  78
PHE A 159
SER A 160
GLY A  37
 None
 1.27A 2lbdA-4ebrA:
undetectable		 2lbdA-4ebrA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ebr UBIQUITIN-LIKE-CONJU
GATING ENZYME ATG10
(Saccharomyces
cerevisiae) 		4 / 7 LYS A  35
LEU A  11
GLN A  12
LEU A  67
 None
 0.96A 2zxwC-4ebrA:
undetectable
2zxwJ-4ebrA:
undetectable		 2zxwC-4ebrA:
20.88
2zxwJ-4ebrA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_2
(GLUCOSYLTRANSFERASE-
SI)		 4ebr UBIQUITIN-LIKE-CONJU
GATING ENZYME ATG10
(Saccharomyces
cerevisiae) 		3 / 3 LEU A  79
TRP A  83
TYR A 128
 None
 1.01A 3aicF-4ebrA:
undetectable		 3aicF-4ebrA:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_C_LEIC16_0
(COIL SER L16D-PEN)		 4ebr UBIQUITIN-LIKE-CONJU
GATING ENZYME ATG10
(Saccharomyces
cerevisiae) 		4 / 6 LEU A  39
GLN A  27
LEU A  40
GLU A  64
 None
 1.12A 3h5gB-4ebrA:
undetectable
3h5gC-4ebrA:
undetectable		 3h5gB-4ebrA:
13.25
3h5gC-4ebrA:
13.25