SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ebz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_B_REMB350_2
(RENIN)		 4ebz CHITIN ELICITOR
RECEPTOR KINASE 1
(Arabidopsis
thaliana) 		4 / 4 VAL A 199
TYR A 209
PRO A 211
PHE A 201
 None
 1.44A 3d91B-4ebzA:
undetectable		 3d91B-4ebzA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)		 4ebz CHITIN ELICITOR
RECEPTOR KINASE 1
(Arabidopsis
thaliana) 		4 / 5 LYS A  25
SER A 159
LEU A  99
SER A 154
 None
 1.25A 3ijxH-4ebzA:
undetectable		 3ijxH-4ebzA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)		 4ebz CHITIN ELICITOR
RECEPTOR KINASE 1
(Arabidopsis
thaliana) 		4 / 4 LYS A  25
SER A 159
LEU A  99
SER A 154
 None
 1.27A 3ik6H-4ebzA:
0.0		 3ik6H-4ebzA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_H_HFZH800_1
(GLUTAMATE RECEPTOR 2)		 4ebz CHITIN ELICITOR
RECEPTOR KINASE 1
(Arabidopsis
thaliana) 		4 / 5 LYS A  25
SER A 159
LEU A  99
SER A 154
 None
 1.27A 3iluH-4ebzA:
undetectable		 3iluH-4ebzA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_A_SAMA1546_0
(CYSTATHIONINE
BETA-SYNTHASE)		 4ebz CHITIN ELICITOR
RECEPTOR KINASE 1
(Arabidopsis
thaliana) 		5 / 11 PHE A 201
ASP A 176
ALA A 182
VAL A 210
ILE A 207
 None
 1.30A 4uuuA-4ebzA:
undetectable
4uuuB-4ebzA:
undetectable		 4uuuA-4ebzA:
20.57
4uuuB-4ebzA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_B_SAMB1548_0
(CYSTATHIONINE
BETA-SYNTHASE)		 4ebz CHITIN ELICITOR
RECEPTOR KINASE 1
(Arabidopsis
thaliana) 		5 / 11 PHE A 201
ASP A 176
ALA A 182
VAL A 210
ILE A 207
 None
 1.30A 4uuuB-4ebzA:
undetectable		 4uuuB-4ebzA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_2
(ENVELOPE
GLYCOPROTEIN 2)		 4ebz CHITIN ELICITOR
RECEPTOR KINASE 1
(Arabidopsis
thaliana) 		4 / 7 LEU A  51
TYR A 121
THR A 125
THR A 126
 None
None
NAG  A 805 (-4.6A)
NAG  A 805 ( 4.1A)
 1.02A 5jq7B-4ebzA:
undetectable		 5jq7B-4ebzA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND502_1
(ADENOSYLHOMOCYSTEINA
SE)		 4ebz CHITIN ELICITOR
RECEPTOR KINASE 1
(Arabidopsis
thaliana) 		3 / 3 LEU A 124
ASN A  70
LEU A  38
 None
 0.72A 6exiD-4ebzA:
undetectable		 6exiD-4ebzA:
16.06