SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ec6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KLM_A_SPPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 4ec6 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 11 LEU A 226
VAL A 310
TYR A 246
PHE A 221
TYR A 282
 None
 1.35A 1klmA-4ec6A:
undetectable		 1klmA-4ec6A:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KLM_A_SPPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 4ec6 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 11 VAL A 310
TYR A 228
TYR A 246
PHE A 221
TYR A 282
 None
 1.23A 1klmA-4ec6A:
undetectable		 1klmA-4ec6A:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WB9_A_CYSA301_0
(GLUTATHIONE
TRANSFERASE SIGMA
CLASS)		 4ec6 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		4 / 5 GLY A 222
ARG A 223
TYR A 282
TYR A 268
 None
 1.41A 2wb9A-4ec6A:
undetectable		 2wb9A-4ec6A:
24.44