SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ec7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_C_115C4_1
(HMG-COA REDUCTASE)		 4ec7 VENOM NERVE GROWTH
FACTOR
(Naja
atra) 		4 / 7 ARG A  67
ASN A  60
ASP A  15
LYS A  57
 None
 1.33A 1hwiC-4ec7A:
undetectable		 1hwiC-4ec7A:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_D_115D3_2
(HMG-COA REDUCTASE)		 4ec7 VENOM NERVE GROWTH
FACTOR
(Naja
atra) 		4 / 7 ARG A  67
ASN A  60
ASP A  15
LYS A  57
 None
 1.33A 1hwiD-4ec7A:
undetectable		 1hwiD-4ec7A:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_A_SAMA501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 4ec7 VENOM NERVE GROWTH
FACTOR
(Naja
atra) 		4 / 8 THR A 104
GLU A  80
THR A  54
SER A  16
 None
 0.97A 2fb2A-4ec7A:
undetectable		 2fb2A-4ec7A:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 4ec7 VENOM NERVE GROWTH
FACTOR
(Naja
atra) 		3 / 3 THR A  27
ASP A  82
GLU A  53
 None
 0.80A 5fa8A-4ec7A:
undetectable		 5fa8A-4ec7A:
19.73