SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ecj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_B_CHDB1130_0
(FATTY ACID-BINDING
PROTEIN)		 4ecj GLUTATHIONE
S-TRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  72
LEU A  82
ILE A  17
ARG A 191
ILE A  55
 None
 1.24A 1tw4B-4ecjA:
undetectable		 1tw4B-4ecjA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_B_SALB900_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4ecj GLUTATHIONE
S-TRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 5 VAL A  93
LEU A  97
ILE A  73
ALA A  76
 None
 0.99A 3n8yB-4ecjA:
undetectable		 3n8yB-4ecjA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NU7_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 4)		 4ecj GLUTATHIONE
S-TRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 8 LEU A 181
ALA A 157
VAL A 175
TYR A 162
 None
 0.98A 5nu7A-4ecjA:
undetectable		 5nu7A-4ecjA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C71_B_NCTB501_1
(AMINE OXIDASE)		 4ecj GLUTATHIONE
S-TRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 8 LEU A   4
TYR A  26
GLU A  20
THR A   6
 None
 0.83A 6c71B-4ecjA:
undetectable		 6c71B-4ecjA:
18.55