SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4eco'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_A_NOVA400_2
(DNA GYRASE SUBUNIT B)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		3 / 3 ASN A 551
PHE A 486
VAL A 524
 None
 0.78A 1kijA-4ecoA:
undetectable		 1kijA-4ecoA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK2_A_ACAA91_1
(TISSUE-TYPE
PLASMINOGEN
ACTIVATOR)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 8 TYR A 579
ASP A 419
HIS A 383
LEU A 391
 None
 1.12A 1pk2A-4ecoA:
undetectable		 1pk2A-4ecoA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 5 PHE A 716
LEU A 763
PHE A 721
SER A 705
 None
 1.33A 1wrkB-4ecoA:
undetectable		 1wrkB-4ecoA:
8.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_D_LEUD1893_0
(AMINOACYL-TRNA
SYNTHETASE)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 8 SER A 382
TYR A 480
HIS A 412
HIS A 383
 None
 1.18A 2bteD-4ecoA:
undetectable		 2bteD-4ecoA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 7 LYS A 613
LEU A 614
LEU A 628
PHE A 652
 None
 0.97A 2dysP-4ecoA:
undetectable
2dysW-4ecoA:
undetectable		 2dysP-4ecoA:
16.35
2dysW-4ecoA:
6.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 7 LYS A 613
LEU A 614
LEU A 628
PHE A 652
 None
 0.95A 2eijP-4ecoA:
undetectable
2eijW-4ecoA:
undetectable		 2eijP-4ecoA:
16.35
2eijW-4ecoA:
6.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 7 LYS A 613
LEU A 614
LEU A 628
PHE A 652
 None
 0.86A 2eimP-4ecoA:
undetectable
2eimW-4ecoA:
undetectable		 2eimP-4ecoA:
16.35
2eimW-4ecoA:
6.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 7 LYS A 613
LEU A 614
LEU A 628
PHE A 652
 None
 0.90A 2einC-4ecoA:
undetectable
2einJ-4ecoA:
undetectable		 2einC-4ecoA:
16.35
2einJ-4ecoA:
6.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_2
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		3 / 3 ASN A 627
ILE A 577
MET A 411
 None
 0.77A 2h42C-4ecoA:
undetectable		 2h42C-4ecoA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_B_BRLB2_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		5 / 12 PHE A 617
CYH A 641
LEU A 650
VAL A 647
LEU A 614
 None
 1.50A 2prgB-4ecoA:
undetectable		 2prgB-4ecoA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA803_0
(FERROCHELATASE)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 5 LEU A 533
PRO A 534
LEU A 537
ILE A 546
 None
 0.80A 2qd4A-4ecoA:
undetectable		 2qd4A-4ecoA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_A_ACTA142_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 5 GLU A 828
PRO A 827
ILE A 830
GLY A 829
 None
 1.07A 2qeuA-4ecoA:
undetectable
2qeuC-4ecoA:
undetectable		 2qeuA-4ecoA:
11.60
2qeuC-4ecoA:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA509_0
(CHORISMATE SYNTHASE)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		3 / 3 ARG A 821
GLN A 892
PRO A 866
 None
 0.98A 2qhfA-4ecoA:
undetectable		 2qhfA-4ecoA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RHM_B_BEZB194_0
(PUTATIVE KINASE)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 5 PRO A 866
ILE A 846
ARG A 847
ASP A 845
 None
 1.50A 2rhmB-4ecoA:
undetectable		 2rhmB-4ecoA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0G_A_LEUA1887_0
(AMINOACYL-TRNA
SYNTHETASE)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 8 SER A 382
TYR A 480
HIS A 412
HIS A 383
 None
 1.14A 2v0gA-4ecoA:
undetectable		 2v0gA-4ecoA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 7 LYS A 613
LEU A 614
LEU A 628
PHE A 652
 None
 0.85A 2zxwC-4ecoA:
undetectable
2zxwJ-4ecoA:
undetectable		 2zxwC-4ecoA:
16.35
2zxwJ-4ecoA:
6.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_D_VD3D2001_1
(VITAMIN D
HYDROXYLASE)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		5 / 12 ILE A 546
LEU A 537
LEU A 530
ALA A 549
LEU A 559
 None
 1.09A 3a50D-4ecoA:
undetectable		 3a50D-4ecoA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CD2_A_MTXA307_1
(DIHYDROFOLATE
REDUCTASE)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		5 / 12 ILE A 786
ILE A 730
SER A 729
PRO A 717
LEU A 745
 None
 1.13A 3cd2A-4ecoA:
undetectable		 3cd2A-4ecoA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKZ_A_ZMRA469_2
(NEURAMINIDASE)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 6 ASP A 425
ARG A 764
ILE A 443
ARG A 423
 None
 1.28A 3ckzA-4ecoA:
undetectable		 3ckzA-4ecoA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZU_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		5 / 12 ILE A 830
GLN A 838
ILE A 811
PHE A 809
LEU A 836
 None
 1.12A 3dzuA-4ecoA:
undetectable		 3dzuA-4ecoA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I9J_B_NCAB302_0
(ADP-RIBOSYL CYCLASE)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 6 GLU A 385
ASN A 483
SER A 355
PHE A 392
 NA  A1001 (-3.5A)
None
None
None
 1.23A 3i9jB-4ecoA:
undetectable		 3i9jB-4ecoA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_C_TFPC202_1
(PROTEIN S100-A4)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		5 / 11 PHE A 426
ASP A 421
LEU A 727
SER A 729
ASP A 676
 None
 1.28A 3ko0A-4ecoA:
undetectable
3ko0B-4ecoA:
undetectable
3ko0C-4ecoA:
undetectable
3ko0D-4ecoA:
undetectable		 3ko0A-4ecoA:
11.07
3ko0B-4ecoA:
11.07
3ko0C-4ecoA:
11.07
3ko0D-4ecoA:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_F_TFPF202_1
(PROTEIN S100-A4)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		5 / 11 ASP A 676
LEU A 727
SER A 729
PHE A 426
ASP A 421
 None
 1.26A 3ko0E-4ecoA:
undetectable
3ko0F-4ecoA:
undetectable
3ko0G-4ecoA:
undetectable
3ko0H-4ecoA:
undetectable		 3ko0E-4ecoA:
11.07
3ko0F-4ecoA:
11.07
3ko0G-4ecoA:
11.07
3ko0H-4ecoA:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_H_TFPH202_1
(PROTEIN S100-A4)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		5 / 12 ASP A 676
LEU A 727
SER A 729
PHE A 426
ASP A 421
 None
 1.28A 3ko0G-4ecoA:
undetectable
3ko0H-4ecoA:
undetectable
3ko0I-4ecoA:
undetectable
3ko0J-4ecoA:
undetectable		 3ko0G-4ecoA:
11.07
3ko0H-4ecoA:
11.07
3ko0I-4ecoA:
11.07
3ko0J-4ecoA:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO202_1
(PROTEIN S100-A4)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		5 / 11 LEU A 727
SER A 729
ASP A 676
PHE A 426
ASP A 421
 None
 1.29A 3ko0O-4ecoA:
undetectable
3ko0P-4ecoA:
undetectable
3ko0Q-4ecoA:
undetectable
3ko0R-4ecoA:
undetectable		 3ko0O-4ecoA:
11.07
3ko0P-4ecoA:
11.07
3ko0Q-4ecoA:
11.07
3ko0R-4ecoA:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ202_1
(PROTEIN S100-A4)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		5 / 10 PHE A 426
ASP A 421
LEU A 727
SER A 729
ASP A 676
 None
 1.29A 3ko0O-4ecoA:
undetectable
3ko0P-4ecoA:
undetectable
3ko0Q-4ecoA:
undetectable
3ko0R-4ecoA:
undetectable		 3ko0O-4ecoA:
11.07
3ko0P-4ecoA:
11.07
3ko0Q-4ecoA:
11.07
3ko0R-4ecoA:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_T_TFPT202_1
(PROTEIN S100-A4)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		5 / 11 ASP A 421
PHE A 426
ASP A 676
LEU A 727
SER A 729
 None
 1.29A 3ko0Q-4ecoA:
undetectable
3ko0R-4ecoA:
undetectable
3ko0S-4ecoA:
undetectable
3ko0T-4ecoA:
undetectable		 3ko0Q-4ecoA:
11.07
3ko0R-4ecoA:
11.07
3ko0S-4ecoA:
11.07
3ko0T-4ecoA:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 8 ASP A 421
PHE A 426
SER A 729
ASP A 676
 None
 0.93A 3m0wE-4ecoA:
undetectable
3m0wF-4ecoA:
undetectable
3m0wG-4ecoA:
undetectable
3m0wH-4ecoA:
undetectable		 3m0wE-4ecoA:
9.90
3m0wF-4ecoA:
9.90
3m0wG-4ecoA:
9.90
3m0wH-4ecoA:
9.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 5 TYR A 790
SER A 789
GLY A 842
ARG A 812
 None
 1.40A 3v4tA-4ecoA:
undetectable
3v4tD-4ecoA:
undetectable		 3v4tA-4ecoA:
20.80
3v4tD-4ecoA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 4 LEU A 533
PRO A 534
LEU A 537
ILE A 546
 None
 0.86A 4f4dB-4ecoA:
undetectable		 4f4dB-4ecoA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_A_RKEA401_1
(PROTON-GATED ION
CHANNEL)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 8 ASP A 561
ASP A 562
VAL A 548
LEU A 585
 None
 1.08A 4f8hA-4ecoA:
undetectable
4f8hB-4ecoA:
undetectable		 4f8hA-4ecoA:
19.72
4f8hB-4ecoA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_D_RKED401_1
(PROTON-GATED ION
CHANNEL)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 8 ASP A 561
ASP A 562
VAL A 548
LEU A 585
 None
 1.09A 4f8hD-4ecoA:
undetectable
4f8hE-4ecoA:
undetectable		 4f8hD-4ecoA:
19.72
4f8hE-4ecoA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOT_A_CE3A205_1
(UNCHARACTERIZED
PROTEIN)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		5 / 12 PHE A 664
GLY A 618
ASN A 639
PHE A 643
LEU A 626
 None
 1.47A 4kotA-4ecoA:
undetectable		 4kotA-4ecoA:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOU_A_C04A206_1
(UNCHARACTERIZED
PROTEIN)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		5 / 10 PHE A 664
GLY A 618
ASN A 639
PHE A 643
LEU A 626
 None
 1.46A 4kouA-4ecoA:
undetectable		 4kouA-4ecoA:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOW_A_CFXA204_1
(UNCHARACTERIZED
PROTEIN)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		5 / 12 PHE A 664
GLY A 618
ASN A 639
PHE A 643
LEU A 626
 None
 1.48A 4kowA-4ecoA:
undetectable		 4kowA-4ecoA:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LMN_A_EUIA503_1
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		5 / 12 LEU A 758
LEU A 727
ILE A 730
ASN A 689
LEU A 745
 None
 1.04A 4lmnA-4ecoA:
undetectable		 4lmnA-4ecoA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_B_20JB601_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 7 TYR A 506
SER A 467
ALA A 503
SER A 500
 None
 1.22A 4lv9A-4ecoA:
undetectable
4lv9B-4ecoA:
undetectable		 4lv9A-4ecoA:
22.73
4lv9B-4ecoA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_C_AERC601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 6 TYR A 525
LEU A 545
GLU A 604
ALA A 624
 None
 0.88A 4nkvC-4ecoA:
undetectable		 4nkvC-4ecoA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_2
(ANDROGEN RECEPTOR)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 6 LEU A 585
ASN A 583
LEU A 603
VAL A 418
 None
 1.19A 4okbA-4ecoA:
undetectable		 4okbA-4ecoA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB301_1
(CHITOSANASE)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		3 / 3 GLY A 393
PRO A 394
GLN A 405
 None
 0.55A 4oltB-4ecoA:
undetectable		 4oltB-4ecoA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		5 / 12 ALA A 616
ILE A 633
ASN A 655
ASN A 631
LEU A 610
 None
 1.19A 4r3aA-4ecoA:
undetectable		 4r3aA-4ecoA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_1
(HYDG PROTEIN)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		3 / 3 GLU A 295
ARG A 350
GLN A 505
 None
 0.73A 4rtbA-4ecoA:
undetectable		 4rtbA-4ecoA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_A_ADNA303_1
(5'/3'-NUCLEOTIDASE
SURE)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		5 / 10 GLY A 581
TYR A 607
ALA A 653
LEU A 606
TYR A 420
 None
 1.20A 4xj7A-4ecoA:
undetectable
4xj7B-4ecoA:
undetectable		 4xj7A-4ecoA:
17.17
4xj7B-4ecoA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVP_B_GBMB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		5 / 12 LEU A 380
VAL A 365
ILE A 369
LEU A 519
LEU A 476
 None
 1.18A 4yvpB-4ecoA:
undetectable		 4yvpB-4ecoA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 7 THR A 755
LEU A 758
THR A 779
LEU A 780
 None
 0.79A 4z90A-4ecoA:
undetectable
4z90B-4ecoA:
undetectable
4z90C-4ecoA:
undetectable
4z90D-4ecoA:
undetectable
4z90E-4ecoA:
undetectable		 4z90A-4ecoA:
20.31
4z90B-4ecoA:
20.31
4z90C-4ecoA:
20.31
4z90D-4ecoA:
20.31
4z90E-4ecoA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 8 THR A 755
LEU A 758
THR A 779
LEU A 780
 None
 0.77A 4z90F-4ecoA:
undetectable
4z90G-4ecoA:
undetectable
4z90H-4ecoA:
undetectable
4z90I-4ecoA:
undetectable
4z90J-4ecoA:
undetectable		 4z90F-4ecoA:
20.31
4z90G-4ecoA:
20.31
4z90H-4ecoA:
20.31
4z90I-4ecoA:
20.31
4z90J-4ecoA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 8 THR A 779
LEU A 780
THR A 755
LEU A 758
 None
 0.78A 4z90F-4ecoA:
undetectable
4z90G-4ecoA:
undetectable
4z90H-4ecoA:
undetectable
4z90I-4ecoA:
undetectable
4z90J-4ecoA:
undetectable		 4z90F-4ecoA:
20.31
4z90G-4ecoA:
20.31
4z90H-4ecoA:
20.31
4z90I-4ecoA:
20.31
4z90J-4ecoA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 6 LYS A 304
ASP A 299
PRO A 366
TYR A 502
 None
 1.24A 5bmvB-4ecoA:
undetectable		 5bmvB-4ecoA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_2
(CYP51 VARIANT1)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		3 / 3 PRO A 422
ILE A 786
SER A 651
 None
 0.71A 5fsaA-4ecoA:
undetectable		 5fsaA-4ecoA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBS_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 8 LEU A 476
LEU A 354
TYR A 480
GLN A 405
 None
 1.01A 5hbsA-4ecoA:
undetectable		 5hbsA-4ecoA:
11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_H_FK5H201_1
(FK506-BINDING
PROTEIN 1)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 8 PHE A 536
VAL A 522
ILE A 546
ILE A 554
 None
 0.77A 5hw8H-4ecoA:
undetectable		 5hw8H-4ecoA:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_1
(SCRFP-TAG,GP41)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		5 / 12 GLY A 342
SER A 355
GLU A 376
LEU A 375
LEU A 378
 None
 1.34A 5nwvA-4ecoA:
undetectable		 5nwvA-4ecoA:
5.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM2_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		5 / 9 LEU A 380
ALA A 379
PHE A 479
VAL A 470
ILE A 369
 None
 0.99A 5om2A-4ecoA:
undetectable
5om2B-4ecoA:
undetectable		 5om2A-4ecoA:
11.09
5om2B-4ecoA:
4.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 9 TYR A 888
LYS A 863
ILE A 862
ILE A 841
 None
 0.70A 5vkqB-4ecoA:
undetectable
5vkqC-4ecoA:
undetectable		 5vkqB-4ecoA:
16.26
5vkqC-4ecoA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_A_RBFA502_2
(RIBOFLAVIN LYASE)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 5 GLN A 892
ASP A 893
SER A 869
ARG A 895
 None
 1.49A 5w4zA-4ecoA:
undetectable		 5w4zA-4ecoA:
8.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 6 LYS A 613
LEU A 614
LEU A 628
PHE A 652
 None
 0.91A 5w97C-4ecoA:
undetectable
5w97J-4ecoA:
undetectable		 5w97C-4ecoA:
16.35
5w97J-4ecoA:
6.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Z_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		5 / 12 ILE A 306
ALA A 302
ALA A 368
GLN A 371
ILE A 463
 None
 1.15A 6a5zD-4ecoA:
undetectable		 6a5zD-4ecoA:
9.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH6_A_017A104_0
(PROTEASE)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		5 / 12 GLY A 360
ALA A 361
VAL A 365
ILE A 306
ILE A 463
 NA  A1001 (-3.7A)
None
None
None
None
 1.00A 6dh6A-4ecoA:
undetectable		 6dh6A-4ecoA:
9.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QXS_B_FOZB403_0
(THYMIDYLATE SYNTHASE)		 4eco UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		5 / 12 PRO A 534
LEU A 537
LEU A 594
LEU A 559
ILE A 580
 None
 0.85A 6qxsB-4ecoA:
undetectable		 6qxsB-4ecoA:
18.72