SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4edn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_C_THAC3_1
(LIVER
CARBOXYLESTERASE I)		 4edn BETA-PARVIN
(Homo
sapiens) 		5 / 12 THR A 349
VAL A 352
LEU A 353
LEU A 295
LEU A 356
 None
 1.15A 1mx1C-4ednA:
undetectable		 1mx1C-4ednA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_E_REAE176_1
(RETINOL BINDING
PROTEIN)		 4edn BETA-PARVIN
(Homo
sapiens) 		5 / 10 LEU A 268
ALA A 322
LEU A 278
GLN A 281
ASP A 284
 None
 1.25A 1rlbE-4ednA:
undetectable		 1rlbE-4ednA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4edn BETA-PARVIN
(Homo
sapiens) 		4 / 4 LEU A 253
PRO A 250
LEU A 245
ARG A 351
 None
 1.43A 3hcoA-4ednA:
undetectable		 3hcoA-4ednA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 4edn BETA-PARVIN
(Homo
sapiens) 		5 / 12 PRO A 309
LEU A 268
VAL A 275
GLN A 281
ALA A 283
 None
 1.20A 4a84A-4ednA:
undetectable		 4a84A-4ednA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GS4_A_ESTA603_2
(ESTROGEN RECEPTOR)		 4edn BETA-PARVIN
(Homo
sapiens) 		4 / 6 LEU A 353
LEU A 295
PHE A 282
LEU A 268
 None
 0.90A 5gs4A-4ednA:
undetectable		 5gs4A-4ednA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GTR_A_ESTA601_2
(ESTROGEN RECEPTOR)		 4edn BETA-PARVIN
(Homo
sapiens) 		4 / 5 LEU A 353
LEU A 295
PHE A 282
LEU A 268
 None
 0.99A 5gtrA-4ednA:
undetectable		 5gtrA-4ednA:
19.75