SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4eei'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_A_ESTA1_1
(ESTROGEN RECEPTOR)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		5 / 10 ALA A  33
GLU A  32
LEU A  28
ARG A  48
ILE A  97
 None
 1.41A 1a52A-4eeiA:
2.7		 1a52A-4eeiA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_A_ESTA1_1
(ESTROGEN RECEPTOR)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		5 / 10 ALA A  33
GLU A  32
LEU A  28
ARG A  48
LEU A 190
 None
 1.41A 1a52A-4eeiA:
2.7		 1a52A-4eeiA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_B_ESTB2_1
(ESTROGEN RECEPTOR)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		5 / 10 ALA A  33
GLU A  32
LEU A  28
ARG A  48
ILE A  97
 None
 1.43A 1a52B-4eeiA:
3.0		 1a52B-4eeiA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1G_B_MTXB171_1
(DIHYDROFOLATE
REDUCTASE)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		5 / 12 ARG A  48
GLU A  78
ILE A  76
LEU A  24
ILE A  53
 None
 1.20A 1d1gB-4eeiA:
undetectable		 1d1gB-4eeiA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_A_ESTA600_1
(ESTROGEN RECEPTOR)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		5 / 9 ALA A  33
GLU A  32
LEU A  28
ARG A  48
ILE A  97
 None
 1.38A 1ereA-4eeiA:
0.7		 1ereA-4eeiA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_B_ESTB600_1
(ESTROGEN RECEPTOR)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		5 / 9 ALA A  33
GLU A  32
LEU A  28
ARG A  48
ILE A  97
 None
 1.39A 1ereB-4eeiA:
0.6		 1ereB-4eeiA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_C_ESTC600_1
(ESTROGEN RECEPTOR)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		5 / 9 ALA A  33
GLU A  32
LEU A  28
ARG A  48
ILE A  97
 None
 1.39A 1ereC-4eeiA:
2.5		 1ereC-4eeiA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_C_ESTC600_1
(ESTROGEN RECEPTOR)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		5 / 9 ALA A  33
GLU A  32
LEU A  28
ARG A  48
LEU A 190
 None
 1.42A 1ereC-4eeiA:
2.5		 1ereC-4eeiA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_D_ESTD600_1
(ESTROGEN RECEPTOR)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		5 / 9 ALA A  33
GLU A  32
LEU A  28
ARG A  48
ILE A  97
 None
 1.39A 1ereD-4eeiA:
2.5		 1ereD-4eeiA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_D_ESTD600_1
(ESTROGEN RECEPTOR)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		5 / 9 ALA A  33
GLU A  32
LEU A  28
ARG A  48
LEU A 190
 None
 1.43A 1ereD-4eeiA:
2.5		 1ereD-4eeiA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		3 / 3 GLN A  52
ILE A  97
HIS A  89
 None
 0.62A 1fm9A-4eeiA:
undetectable		 1fm9A-4eeiA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1502_0
(FERROCHELATASE)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		4 / 8 ARG A  37
LEU A  34
VAL A  92
GLY A 182
 None
 1.00A 1hrkA-4eeiA:
undetectable		 1hrkA-4eeiA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		3 / 3 GLN A  52
ILE A  97
HIS A  89
 None
 0.66A 1k74A-4eeiA:
undetectable		 1k74A-4eeiA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		4 / 5 PHE A 359
PHE A 355
MET A 409
SER A 387
 None
 1.28A 1wrkB-4eeiA:
undetectable		 1wrkB-4eeiA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_B_MMZB501_1
(MONOOXYGENASE)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		3 / 3 ASN A  18
TYR A 112
SER A  11
 None
EDO  A 505 (-3.6A)
None
 0.90A 2gvcB-4eeiA:
undetectable		 2gvcB-4eeiA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_E_MMZE501_1
(MONOOXYGENASE)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		3 / 3 ASN A  18
TYR A 112
SER A  11
 None
EDO  A 505 (-3.6A)
None
 0.90A 2gvcE-4eeiA:
undetectable		 2gvcE-4eeiA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_A_PRLA1188_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		4 / 8 ASN A  18
ILE A  13
ASP A 108
ARG A 107
 None
 0.76A 2v57A-4eeiA:
1.0		 2v57A-4eeiA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_C_PRLC1187_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		4 / 8 ASN A  18
ILE A  13
ASP A 108
ARG A 107
 None
 0.74A 2v57C-4eeiA:
1.0		 2v57C-4eeiA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_A_TOPA1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		5 / 11 ILE A 229
LEU A 277
ILE A 233
SER A 123
PHE A 161
 None
None
None
EDO  A 507 (-3.0A)
None
 1.01A 2w9sA-4eeiA:
undetectable		 2w9sA-4eeiA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_B_TOPB1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		5 / 11 ILE A 229
LEU A 277
ILE A 233
SER A 123
PHE A 161
 None
None
None
EDO  A 507 (-3.0A)
None
 1.00A 2w9sB-4eeiA:
undetectable		 2w9sB-4eeiA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_B_SAMB298_0
(PUTATIVE
MODIFICATION
METHYLASE)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		5 / 12 ALA A 220
SER A 286
ALA A 281
GLY A 227
LEU A 222
 None
 1.10A 2zifB-4eeiA:
undetectable		 2zifB-4eeiA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		4 / 7 PHE A  80
GLU A  78
SER A  75
ARG A  50
 None
 1.42A 3dqtA-4eeiA:
undetectable
3dqtB-4eeiA:
1.7		 3dqtA-4eeiA:
21.05
3dqtB-4eeiA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5T_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		4 / 7 SER A  75
ARG A  50
PHE A  80
GLU A  78
 None
 1.41A 3n5tA-4eeiA:
undetectable
3n5tB-4eeiA:
undetectable		 3n5tA-4eeiA:
20.50
3n5tB-4eeiA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_B_SAMB302_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		4 / 5 TYR A 312
SER A 224
ASP A  99
ILE A 214
 None
 1.10A 3uj7B-4eeiA:
undetectable		 3uj7B-4eeiA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UUD_B_ESTB600_1
(ESTROGEN RECEPTOR)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		5 / 10 ALA A  33
GLU A  32
LEU A  28
ARG A  48
LEU A 190
 None
 1.43A 3uudB-4eeiA:
2.7		 3uudB-4eeiA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		4 / 8 GLU A  27
GLU A 195
GLY A 182
SER A 181
 None
 0.95A 4f93B-4eeiA:
undetectable		 4f93B-4eeiA:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5J_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		4 / 7 PHE A  80
GLU A  78
SER A  75
ARG A  50
 None
 1.41A 4k5jA-4eeiA:
undetectable
4k5jB-4eeiA:
undetectable		 4k5jA-4eeiA:
20.54
4k5jB-4eeiA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MX0_A_BCZA513_0
(NEURAMINIDASE)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		5 / 12 LEU A 104
ARG A 107
SER A 103
ARG A 218
GLU A 207
 None
 1.43A 4mx0A-4eeiA:
undetectable		 4mx0A-4eeiA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADL_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		4 / 7 PHE A  80
GLU A  78
SER A  75
ARG A  50
 None
 1.40A 5adlA-4eeiA:
undetectable
5adlB-4eeiA:
undetectable		 5adlA-4eeiA:
20.54
5adlB-4eeiA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXE_B_ESTB1000_1
(ESTROGEN RECEPTOR)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		5 / 10 ALA A  33
GLU A  32
LEU A  28
ARG A  48
LEU A 190
 None
 1.44A 5dxeB-4eeiA:
2.5		 5dxeB-4eeiA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ3_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		4 / 7 PHE A  80
GLU A  78
SER A  75
ARG A  50
 None
 1.44A 5fj3A-4eeiA:
undetectable
5fj3B-4eeiA:
undetectable		 5fj3A-4eeiA:
20.54
5fj3B-4eeiA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HYR_B_ESTB601_1
(ESTROGEN RECEPTOR)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		5 / 11 ALA A  33
GLU A  32
LEU A  28
ARG A  48
LEU A 190
 None
 1.45A 5hyrB-4eeiA:
2.3		 5hyrB-4eeiA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		4 / 6 SER A  75
ARG A  50
PHE A  80
GLU A  78
 None
 1.40A 5uo8A-4eeiA:
undetectable
5uo8B-4eeiA:
undetectable		 5uo8A-4eeiA:
19.18
5uo8B-4eeiA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		5 / 10 TYR A  20
ILE A  76
ILE A  47
LEU A  31
ILE A  69
 None
 1.37A 5vkqA-4eeiA:
2.4
5vkqD-4eeiA:
2.4		 5vkqA-4eeiA:
12.54
5vkqD-4eeiA:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		5 / 10 ILE A  69
TYR A  20
ILE A  76
ILE A  47
LEU A  31
 None
 1.31A 5vkqA-4eeiA:
2.4
5vkqB-4eeiA:
2.3		 5vkqA-4eeiA:
12.54
5vkqB-4eeiA:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		5 / 10 ILE A  69
TYR A  20
ILE A  76
ILE A  47
LEU A  31
 None
 1.35A 5vkqC-4eeiA:
2.4
5vkqD-4eeiA:
2.4		 5vkqC-4eeiA:
12.54
5vkqD-4eeiA:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV7_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		4 / 7 PHE A  80
GLU A  78
SER A  75
ARG A  50
 None
 1.40A 5vv7A-4eeiA:
undetectable
5vv7B-4eeiA:
1.8		 5vv7A-4eeiA:
20.54
5vv7B-4eeiA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVN_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		4 / 7 PHE A  80
GLU A  78
SER A  75
ARG A  50
 None
 1.41A 5vvnA-4eeiA:
undetectable
5vvnB-4eeiA:
undetectable		 5vvnA-4eeiA:
20.54
5vvnB-4eeiA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGD_A_ESTA601_1
(ESTROGEN RECEPTOR)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		5 / 9 ALA A  33
GLU A  32
LEU A  28
ARG A  48
LEU A 190
 None
 1.43A 5wgdA-4eeiA:
2.7		 5wgdA-4eeiA:
11.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGQ_B_ESTB601_1
(ESTROGEN RECEPTOR)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		5 / 10 ALA A  33
GLU A  32
LEU A  28
ARG A  48
LEU A 190
 None
 1.44A 5wgqB-4eeiA:
undetectable		 5wgqB-4eeiA:
11.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		3 / 3 GLN A  52
ILE A  97
HIS A  89
 None
 0.67A 5z12B-4eeiA:
undetectable		 5z12B-4eeiA:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_B_H4BB501_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		4 / 7 SER A  75
ARG A  50
PHE A  80
GLU A  78
 None
 1.42A 6av6A-4eeiA:
undetectable
6av6B-4eeiA:
undetectable		 6av6A-4eeiA:
10.90
6av6B-4eeiA:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		4 / 7 PHE A  80
GLU A  78
SER A  75
ARG A  50
 None
 1.41A 6av6C-4eeiA:
undetectable
6av6D-4eeiA:
0.0		 6av6C-4eeiA:
10.90
6av6D-4eeiA:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		4 / 7 SER A  75
ARG A  50
PHE A  80
GLU A  78
 None
 1.43A 6av7A-4eeiA:
undetectable
6av7B-4eeiA:
0.0		 6av7A-4eeiA:
10.90
6av7B-4eeiA:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ESM_A_PZEA307_1
(MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9)		 4eei ADENYLOSUCCINATE
LYASE
(Francisella
tularensis) 		3 / 3 TYR A 252
HIS A 244
PHE A 249
 None
 0.89A 6esmA-4eeiA:
undetectable		 6esmA-4eeiA:
10.73