SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4eew'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_C_URFC2081_1
(URIDINE
PHOSPHORYLASE)		 4eew LARGE PROLINE-RICH
PROTEIN BAG6
(Homo
sapiens) 		4 / 7 GLY A  34
GLN A  73
ILE A  32
VAL A  33
 None
 1.05A 1rxcC-4eewA:
undetectable		 1rxcC-4eewA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)		 4eew LARGE PROLINE-RICH
PROTEIN BAG6
(Homo
sapiens) 		4 / 7 GLY A  34
GLN A  73
ILE A  32
VAL A  33
 None
 1.07A 1rxcL-4eewA:
undetectable		 1rxcL-4eewA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_A_URFA254_1
(URIDINE
PHOSPHORYLASE)		 4eew LARGE PROLINE-RICH
PROTEIN BAG6
(Homo
sapiens) 		4 / 6 GLY A  34
GLN A  73
ILE A  32
VAL A  33
 None
 1.08A 3kvvA-4eewA:
undetectable		 3kvvA-4eewA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_B_URFB254_1
(URIDINE
PHOSPHORYLASE)		 4eew LARGE PROLINE-RICH
PROTEIN BAG6
(Homo
sapiens) 		4 / 6 GLY A  34
GLN A  73
ILE A  32
VAL A  33
 None
 1.06A 3kvvB-4eewA:
undetectable		 3kvvB-4eewA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_C_URFC254_1
(URIDINE
PHOSPHORYLASE)		 4eew LARGE PROLINE-RICH
PROTEIN BAG6
(Homo
sapiens) 		4 / 6 GLY A  34
GLN A  73
ILE A  32
VAL A  33
 None
 1.06A 3kvvC-4eewA:
undetectable		 3kvvC-4eewA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_D_URFD254_1
(URIDINE
PHOSPHORYLASE)		 4eew LARGE PROLINE-RICH
PROTEIN BAG6
(Homo
sapiens) 		4 / 6 GLY A  34
GLN A  73
ILE A  32
VAL A  33
 None
 1.05A 3kvvD-4eewA:
undetectable		 3kvvD-4eewA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_E_URFE254_1
(URIDINE
PHOSPHORYLASE)		 4eew LARGE PROLINE-RICH
PROTEIN BAG6
(Homo
sapiens) 		4 / 6 GLY A  34
GLN A  73
ILE A  32
VAL A  33
 None
 1.10A 3kvvE-4eewA:
undetectable		 3kvvE-4eewA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_F_URFF254_1
(URIDINE
PHOSPHORYLASE)		 4eew LARGE PROLINE-RICH
PROTEIN BAG6
(Homo
sapiens) 		4 / 6 GLY A  34
GLN A  73
ILE A  32
VAL A  33
 None
 1.09A 3kvvF-4eewA:
undetectable		 3kvvF-4eewA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_B_URFB1301_1
(URIDINE
PHOSPHORYLASE)		 4eew LARGE PROLINE-RICH
PROTEIN BAG6
(Homo
sapiens) 		4 / 7 GLY A  34
GLN A  73
ILE A  32
VAL A  33
 None
 1.06A 4e1vB-4eewA:
undetectable		 4e1vB-4eewA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_F_URFF1301_1
(URIDINE
PHOSPHORYLASE)		 4eew LARGE PROLINE-RICH
PROTEIN BAG6
(Homo
sapiens) 		4 / 6 GLY A  34
GLN A  73
ILE A  32
VAL A  33
 None
 1.12A 4e1vF-4eewA:
undetectable		 4e1vF-4eewA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XYZ_A_ACTA103_0
(POLYUBIQUITIN-C)		 4eew LARGE PROLINE-RICH
PROTEIN BAG6
(Homo
sapiens) 		4 / 4 LEU A  24
ILE A  60
HIS A  83
VAL A  85
 None
 0.80A 4xyzA-4eewA:
13.1		 4xyzA-4eewA:
29.55