SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4efo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_2
(ADENOSINE KINASE)		 4efo SERINE/THREONINE-PRO
TEIN KINASE TBK1
(Homo
sapiens) 		4 / 4 ALA A 367
VAL A 310
PHE A 335
THR A 373
 None
 1.33A 2pkkA-4efoA:
undetectable		 2pkkA-4efoA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PBH_A_BEZA401_0
(TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT, PUTATIVE)		 4efo SERINE/THREONINE-PRO
TEIN KINASE TBK1
(Homo
sapiens) 		5 / 12 ILE A 379
HIS A 336
ALA A 332
ARG A 365
LEU A 359
 None
 1.34A 4pbhA-4efoA:
undetectable		 4pbhA-4efoA:
13.41