SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4eg9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3002_1
(SERUM ALBUMIN)		 4eg9 UNCHARACTERIZED
PROTEIN
SAOUHSC_02783
(Staphylococcus
aureus) 		4 / 8 ASN A 197
LEU A 201
ARG A 204
LEU A 233
 None
 1.12A 1hk3A-4eg9A:
undetectable		 1hk3A-4eg9A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W76_A_GNTA1538_1
(ACETYLCHOLINESTERASE)		 4eg9 UNCHARACTERIZED
PROTEIN
SAOUHSC_02783
(Staphylococcus
aureus) 		5 / 11 GLY A 163
TYR A  47
PHE A 165
PHE A 247
PHE A 235
 None
 1.12A 1w76A-4eg9A:
undetectable		 1w76A-4eg9A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA803_0
(FERROCHELATASE)		 4eg9 UNCHARACTERIZED
PROTEIN
SAOUHSC_02783
(Staphylococcus
aureus) 		4 / 5 LEU A 144
PRO A 145
LEU A 149
ILE A 153
 None
 0.89A 2qd4A-4eg9A:
undetectable		 2qd4A-4eg9A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y04_B_68HB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4eg9 UNCHARACTERIZED
PROTEIN
SAOUHSC_02783
(Staphylococcus
aureus) 		5 / 12 THR A  49
VAL A 160
PHE A  55
SER A  78
ASN A 136
 None
 1.11A 2y04B-4eg9A:
undetectable		 2y04B-4eg9A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_1
(N-METHYLTRANSFERASE)		 4eg9 UNCHARACTERIZED
PROTEIN
SAOUHSC_02783
(Staphylococcus
aureus) 		3 / 3 TYR A 205
TYR A 162
GLU A 152
 None
 0.91A 3pfgA-4eg9A:
2.3		 3pfgA-4eg9A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4eg9 UNCHARACTERIZED
PROTEIN
SAOUHSC_02783
(Staphylococcus
aureus) 		4 / 8 VAL A  95
ILE A  75
ASN A  77
GLU A 126
 None
 0.74A 4a97C-4eg9A:
undetectable		 4a97C-4eg9A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_E_ZPCE1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4eg9 UNCHARACTERIZED
PROTEIN
SAOUHSC_02783
(Staphylococcus
aureus) 		4 / 8 VAL A  95
ILE A  75
ASN A  77
GLU A 126
 None
 0.79A 4a97D-4eg9A:
undetectable		 4a97D-4eg9A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4eg9 UNCHARACTERIZED
PROTEIN
SAOUHSC_02783
(Staphylococcus
aureus) 		4 / 8 VAL A  95
ILE A  75
ASN A  77
GLU A 126
 None
 0.70A 4a97G-4eg9A:
undetectable		 4a97G-4eg9A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_I_ZPCI1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4eg9 UNCHARACTERIZED
PROTEIN
SAOUHSC_02783
(Staphylococcus
aureus) 		4 / 7 VAL A  95
ILE A  75
ASN A  77
GLU A 126
 None
 0.63A 4a97H-4eg9A:
undetectable		 4a97H-4eg9A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_J_ZPCJ1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4eg9 UNCHARACTERIZED
PROTEIN
SAOUHSC_02783
(Staphylococcus
aureus) 		4 / 8 VAL A  95
ILE A  75
ASN A  77
GLU A 126
 None
 0.74A 4a97I-4eg9A:
undetectable		 4a97I-4eg9A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AGA_A_ACTA1131_0
(LYSOZYME C)		 4eg9 UNCHARACTERIZED
PROTEIN
SAOUHSC_02783
(Staphylococcus
aureus) 		3 / 3 ASN A  41
ASP A 167
ASN A 169
 None
 0.68A 4agaA-4eg9A:
undetectable		 4agaA-4eg9A:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4eg9 UNCHARACTERIZED
PROTEIN
SAOUHSC_02783
(Staphylococcus
aureus) 		4 / 4 LEU A 144
PRO A 145
LEU A 149
ILE A 153
 None
 0.95A 4f4dB-4eg9A:
undetectable		 4f4dB-4eg9A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_B_CLQB303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4eg9 UNCHARACTERIZED
PROTEIN
SAOUHSC_02783
(Staphylococcus
aureus) 		5 / 11 PHE A 156
ILE A 138
PHE A 158
GLY A 107
TYR A  97
 None
 1.33A 4fglA-4eg9A:
undetectable
4fglB-4eg9A:
undetectable		 4fglA-4eg9A:
20.75
4fglB-4eg9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 4eg9 UNCHARACTERIZED
PROTEIN
SAOUHSC_02783
(Staphylococcus
aureus) 		4 / 6 THR A  43
LEU A 216
GLN A 190
LEU A 191
 None
 1.24A 4nc3A-4eg9A:
undetectable		 4nc3A-4eg9A:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJB_A_198A1001_2
(ANDROGEN RECEPTOR)		 4eg9 UNCHARACTERIZED
PROTEIN
SAOUHSC_02783
(Staphylococcus
aureus) 		4 / 7 ASN A 136
ILE A 139
ILE A 138
VAL A 131
 None
 0.86A 4ojbA-4eg9A:
undetectable		 4ojbA-4eg9A:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_2
(ANDROGEN RECEPTOR)		 4eg9 UNCHARACTERIZED
PROTEIN
SAOUHSC_02783
(Staphylococcus
aureus) 		4 / 6 ASN A 136
ILE A 139
ILE A 138
VAL A 131
 None
 0.86A 4olmA-4eg9A:
undetectable		 4olmA-4eg9A:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LBT_A_6T0A304_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4eg9 UNCHARACTERIZED
PROTEIN
SAOUHSC_02783
(Staphylococcus
aureus) 		5 / 10 GLY A 107
TYR A  97
PHE A 156
ILE A 138
PHE A 158
 None
 1.37A 5lbtA-4eg9A:
undetectable
5lbtB-4eg9A:
undetectable		 5lbtA-4eg9A:
19.57
5lbtB-4eg9A:
19.57