SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4egt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_2
(PROTEIN (ADENOSINE
KINASE))		 4egt MAJOR CAPSID PROTEIN
VP60
(Rabbit
hemorrhagic
disease
virus) 		3 / 3 LEU A 547
SER A 465
ASN A 253
 None
 0.71A 1bx4A-4egtA:
undetectable		 1bx4A-4egtA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EUP_A_ASDA452_1
(CYTOCHROME P450ERYF)		 4egt MAJOR CAPSID PROTEIN
VP60
(Rabbit
hemorrhagic
disease
virus) 		4 / 8 PHE A 519
ILE A 545
LEU A 544
LEU A 547
 None
 0.60A 1eupA-4egtA:
undetectable		 1eupA-4egtA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_0
(SUN PROTEIN)		 4egt MAJOR CAPSID PROTEIN
VP60
(Rabbit
hemorrhagic
disease
virus) 		5 / 12 ALA A 452
GLY A 270
GLY A 269
ASP A 531
GLY A 527
 None
 1.05A 1sqfA-4egtA:
undetectable		 1sqfA-4egtA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 4egt MAJOR CAPSID PROTEIN
VP60
(Rabbit
hemorrhagic
disease
virus) 		4 / 7 GLY A 488
THR A 487
TYR A 436
ASN A 255
 None
 1.09A 2g70A-4egtA:
undetectable		 2g70A-4egtA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 4egt MAJOR CAPSID PROTEIN
VP60
(Rabbit
hemorrhagic
disease
virus) 		4 / 7 GLY A 488
THR A 487
TYR A 436
ASN A 255
 None
 1.08A 2g70B-4egtA:
undetectable		 2g70B-4egtA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_B_ADNB2_1
(YTAA PROTEIN)		 4egt MAJOR CAPSID PROTEIN
VP60
(Rabbit
hemorrhagic
disease
virus) 		4 / 6 ILE A 360
PRO A 333
LEU A 378
ILE A 295
 None
 1.00A 2q83B-4egtA:
undetectable		 2q83B-4egtA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_A_BEZA1222_0
(PEROXIREDOXIN 6)		 4egt MAJOR CAPSID PROTEIN
VP60
(Rabbit
hemorrhagic
disease
virus) 		4 / 7 THR A 459
PRO A 460
VAL A 267
PRO A 454
 None
 1.02A 2v2gA-4egtA:
undetectable
2v2gB-4egtA:
undetectable		 2v2gA-4egtA:
22.04
2v2gB-4egtA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_B_BEZB1220_0
(PEROXIREDOXIN 6)		 4egt MAJOR CAPSID PROTEIN
VP60
(Rabbit
hemorrhagic
disease
virus) 		4 / 7 PRO A 454
THR A 459
PRO A 460
VAL A 267
 None
 1.04A 2v2gA-4egtA:
undetectable
2v2gB-4egtA:
undetectable		 2v2gA-4egtA:
22.04
2v2gB-4egtA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_C_BEZC1222_0
(PEROXIREDOXIN 6)		 4egt MAJOR CAPSID PROTEIN
VP60
(Rabbit
hemorrhagic
disease
virus) 		4 / 7 THR A 459
PRO A 460
VAL A 267
PRO A 454
 None
 1.07A 2v2gC-4egtA:
undetectable
2v2gD-4egtA:
undetectable		 2v2gC-4egtA:
22.04
2v2gD-4egtA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_D_BEZD1221_0
(PEROXIREDOXIN 6)		 4egt MAJOR CAPSID PROTEIN
VP60
(Rabbit
hemorrhagic
disease
virus) 		4 / 7 PRO A 454
THR A 459
PRO A 460
VAL A 267
 None
 1.00A 2v2gC-4egtA:
undetectable
2v2gD-4egtA:
undetectable		 2v2gC-4egtA:
22.04
2v2gD-4egtA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_C_BEZC1218_0
(PEROXIREDOXIN 6.)		 4egt MAJOR CAPSID PROTEIN
VP60
(Rabbit
hemorrhagic
disease
virus) 		4 / 8 THR A 459
PRO A 460
VAL A 267
PRO A 454
 None
 0.98A 2v41C-4egtA:
undetectable
2v41D-4egtA:
undetectable		 2v41C-4egtA:
22.04
2v41D-4egtA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_D_BEZD1222_0
(PEROXIREDOXIN 6.)		 4egt MAJOR CAPSID PROTEIN
VP60
(Rabbit
hemorrhagic
disease
virus) 		4 / 8 PRO A 454
THR A 459
PRO A 460
VAL A 267
 None
 1.00A 2v41C-4egtA:
undetectable
2v41D-4egtA:
undetectable		 2v41C-4egtA:
22.04
2v41D-4egtA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_E_BEZE1222_0
(PEROXIREDOXIN 6.)		 4egt MAJOR CAPSID PROTEIN
VP60
(Rabbit
hemorrhagic
disease
virus) 		4 / 7 THR A 459
PRO A 460
VAL A 267
PRO A 454
 None
 1.00A 2v41E-4egtA:
undetectable
2v41F-4egtA:
undetectable		 2v41E-4egtA:
22.04
2v41F-4egtA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_F_BEZF1222_0
(PEROXIREDOXIN 6.)		 4egt MAJOR CAPSID PROTEIN
VP60
(Rabbit
hemorrhagic
disease
virus) 		4 / 7 PRO A 454
THR A 459
PRO A 460
VAL A 267
 None
 0.94A 2v41E-4egtA:
undetectable
2v41F-4egtA:
undetectable		 2v41E-4egtA:
22.04
2v41F-4egtA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_G_BEZG1222_0
(PEROXIREDOXIN 6.)		 4egt MAJOR CAPSID PROTEIN
VP60
(Rabbit
hemorrhagic
disease
virus) 		4 / 8 THR A 459
PRO A 460
VAL A 267
PRO A 454
 None
 0.99A 2v41G-4egtA:
undetectable
2v41H-4egtA:
undetectable		 2v41G-4egtA:
22.04
2v41H-4egtA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_H_BEZH1222_0
(PEROXIREDOXIN 6.)		 4egt MAJOR CAPSID PROTEIN
VP60
(Rabbit
hemorrhagic
disease
virus) 		4 / 8 PRO A 454
THR A 459
PRO A 460
VAL A 267
 None
 0.98A 2v41G-4egtA:
undetectable
2v41H-4egtA:
undetectable		 2v41G-4egtA:
22.04
2v41H-4egtA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_2
(GLUCOSYLTRANSFERASE-
SI)		 4egt MAJOR CAPSID PROTEIN
VP60
(Rabbit
hemorrhagic
disease
virus) 		3 / 3 LEU A 528
TRP A 278
TYR A 533
 None
 0.92A 3aicA-4egtA:
undetectable		 3aicA-4egtA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_2
(GLUCOSYLTRANSFERASE-
SI)		 4egt MAJOR CAPSID PROTEIN
VP60
(Rabbit
hemorrhagic
disease
virus) 		3 / 3 LEU A 528
TRP A 278
TYR A 533
 None
 0.92A 3aicB-4egtA:
undetectable		 3aicB-4egtA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_2
(GLUCOSYLTRANSFERASE-
SI)		 4egt MAJOR CAPSID PROTEIN
VP60
(Rabbit
hemorrhagic
disease
virus) 		3 / 3 LEU A 528
TRP A 278
TYR A 533
 None
 0.93A 3aicE-4egtA:
undetectable		 3aicE-4egtA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_2
(GLUCOSYLTRANSFERASE-
SI)		 4egt MAJOR CAPSID PROTEIN
VP60
(Rabbit
hemorrhagic
disease
virus) 		3 / 3 LEU A 528
TRP A 278
TYR A 533
 None
 0.98A 3aicF-4egtA:
undetectable		 3aicF-4egtA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_2
(GLUCOSYLTRANSFERASE-
SI)		 4egt MAJOR CAPSID PROTEIN
VP60
(Rabbit
hemorrhagic
disease
virus) 		3 / 3 LEU A 528
TRP A 278
TYR A 533
 None
 0.96A 3aicG-4egtA:
undetectable		 3aicG-4egtA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_2
(GLUCOSYLTRANSFERASE-
SI)		 4egt MAJOR CAPSID PROTEIN
VP60
(Rabbit
hemorrhagic
disease
virus) 		3 / 3 LEU A 528
TRP A 278
TYR A 533
 None
 0.93A 3aicH-4egtA:
undetectable		 3aicH-4egtA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF502_3
(PHOSPHOLIPASE A2)		 4egt MAJOR CAPSID PROTEIN
VP60
(Rabbit
hemorrhagic
disease
virus) 		5 / 12 VAL A 407
GLY A 410
SER A 303
PHE A 315
SER A 301
 None
 1.13A 3bjwF-4egtA:
undetectable		 3bjwF-4egtA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PRS_A_RITA1001_2
(ENDOTHIAPEPSIN)		 4egt MAJOR CAPSID PROTEIN
VP60
(Rabbit
hemorrhagic
disease
virus) 		5 / 12 ASP A 531
GLY A 488
ASP A 338
THR A 273
ILE A 443
 None
 1.13A 3prsA-4egtA:
undetectable		 3prsA-4egtA:
25.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TVX_A_PNXA902_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4A)		 4egt MAJOR CAPSID PROTEIN
VP60
(Rabbit
hemorrhagic
disease
virus) 		5 / 9 LEU A 243
PRO A 491
THR A 495
GLN A 490
PHE A 534
 None
 1.42A 3tvxA-4egtA:
undetectable		 3tvxA-4egtA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A202_1
(POL POLYPROTEIN)		 4egt MAJOR CAPSID PROTEIN
VP60
(Rabbit
hemorrhagic
disease
virus) 		5 / 9 LEU A 498
ASP A 254
ILE A 261
ILE A 526
LEU A 242
 None
 1.13A 3u7sA-4egtA:
undetectable		 3u7sA-4egtA:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PBH_A_BEZA401_0
(TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT, PUTATIVE)		 4egt MAJOR CAPSID PROTEIN
VP60
(Rabbit
hemorrhagic
disease
virus) 		5 / 12 ILE A 461
THR A 538
LEU A 264
LEU A 517
PHE A 567
 None
 1.37A 4pbhA-4egtA:
undetectable		 4pbhA-4egtA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4egt MAJOR CAPSID PROTEIN
VP60
(Rabbit
hemorrhagic
disease
virus) 		5 / 12 GLY A 321
ILE A 404
GLY A 356
LEU A 418
HIS A 297
 None
 1.13A 4zdyA-4egtA:
undetectable		 4zdyA-4egtA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA503_1
(CYTOCHROME P450 2C9)		 4egt MAJOR CAPSID PROTEIN
VP60
(Rabbit
hemorrhagic
disease
virus) 		4 / 5 GLY A 537
THR A 538
ASN A 458
LYS A 457
 None
 1.20A 5x23A-4egtA:
undetectable		 5x23A-4egtA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YN6_A_SAMA401_0
(NSP16 PROTEIN)		 4egt MAJOR CAPSID PROTEIN
VP60
(Rabbit
hemorrhagic
disease
virus) 		5 / 12 GLY A 286
PRO A 447
GLY A 448
ASN A 275
ASP A 334
 None
 1.32A 5yn6A-4egtA:
undetectable		 5yn6A-4egtA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YNI_A_SAMA401_0
(NSP16 PROTEIN)		 4egt MAJOR CAPSID PROTEIN
VP60
(Rabbit
hemorrhagic
disease
virus) 		5 / 12 GLY A 286
PRO A 447
GLY A 448
ASN A 275
ASP A 334
 None
 1.32A 5yniA-4egtA:
undetectable		 5yniA-4egtA:
23.47