SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ei0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT6_B_DESB128_1
(TRANSTHYRETIN)		 4ei0 UNCHARACTERIZED
HYPOTHETICAL PROTEIN
(Parabacteroides
merdae) 		4 / 5 LYS A 213
LEU A 210
ALA A 212
SER A 247
 None
 1.05A 1tt6B-4ei0A:
undetectable		 1tt6B-4ei0A:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_B_STIB600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4ei0 UNCHARACTERIZED
HYPOTHETICAL PROTEIN
(Parabacteroides
merdae) 		4 / 6 LEU A 190
VAL A 324
VAL A 328
ILE A 198
 None
 1.24A 2hyyB-4ei0A:
undetectable		 2hyyB-4ei0A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_2
(PROGESTERONE
RECEPTOR)		 4ei0 UNCHARACTERIZED
HYPOTHETICAL PROTEIN
(Parabacteroides
merdae) 		4 / 7 LEU A 295
LEU A 178
MET A 255
TYR A 231
 None
 1.20A 2w8yA-4ei0A:
undetectable		 2w8yA-4ei0A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1160_1
(ALLERGEN ARG R 1)		 4ei0 UNCHARACTERIZED
HYPOTHETICAL PROTEIN
(Parabacteroides
merdae) 		4 / 7 SER A 170
TYR A 331
ILE A  52
ASP A 277
 None
None
GOL  A 400 (-4.7A)
None
 1.19A 2x45B-4ei0A:
undetectable		 2x45B-4ei0A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1160_1
(ALLERGEN ARG R 1)		 4ei0 UNCHARACTERIZED
HYPOTHETICAL PROTEIN
(Parabacteroides
merdae) 		4 / 7 SER A 170
TYR A 331
ILE A  52
ASP A 277
 None
None
GOL  A 400 (-4.7A)
None
 1.21A 2x45C-4ei0A:
undetectable		 2x45C-4ei0A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K5V_A_STIA2_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4ei0 UNCHARACTERIZED
HYPOTHETICAL PROTEIN
(Parabacteroides
merdae) 		4 / 6 LEU A 190
VAL A 324
VAL A 328
ILE A 198
 None
 1.20A 3k5vA-4ei0A:
undetectable		 3k5vA-4ei0A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K5V_B_STIB2_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4ei0 UNCHARACTERIZED
HYPOTHETICAL PROTEIN
(Parabacteroides
merdae) 		4 / 6 LEU A 190
VAL A 324
VAL A 328
ILE A 198
 None
 1.23A 3k5vB-4ei0A:
undetectable		 3k5vB-4ei0A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG801_0
(GLUTAMATE RECEPTOR 2)		 4ei0 UNCHARACTERIZED
HYPOTHETICAL PROTEIN
(Parabacteroides
merdae) 		3 / 3 PRO A  50
SER A 170
ASN A  55
 None
 0.63A 3lslG-4ei0A:
undetectable		 3lslG-4ei0A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKI_A_IMNA201_1
(TRANSTHYRETIN)		 4ei0 UNCHARACTERIZED
HYPOTHETICAL PROTEIN
(Parabacteroides
merdae) 		3 / 3 LYS A 213
LEU A 210
ALA A 212
 None
 0.61A 4ikiA-4ei0A:
undetectable		 4ikiA-4ei0A:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_A_ACTA403_0
(D-ALANINE--D-ALANINE
LIGASE)		 4ei0 UNCHARACTERIZED
HYPOTHETICAL PROTEIN
(Parabacteroides
merdae) 		4 / 6 TYR A 231
GLY A 294
SER A 227
LEU A 226
 None
 1.05A 5bphA-4ei0A:
undetectable		 5bphA-4ei0A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_B_ACTB404_0
(D-ALANINE--D-ALANINE
LIGASE)		 4ei0 UNCHARACTERIZED
HYPOTHETICAL PROTEIN
(Parabacteroides
merdae) 		4 / 7 TYR A 231
GLY A 294
SER A 227
LEU A 226
 None
 1.01A 5bphB-4ei0A:
undetectable		 5bphB-4ei0A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_C_ACTC403_0
(D-ALANINE--D-ALANINE
LIGASE)		 4ei0 UNCHARACTERIZED
HYPOTHETICAL PROTEIN
(Parabacteroides
merdae) 		4 / 4 TYR A 231
GLY A 294
SER A 227
LEU A 226
 None
 1.08A 5bphC-4ei0A:
undetectable		 5bphC-4ei0A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_D_ACTD403_0
(D-ALANINE--D-ALANINE
LIGASE)		 4ei0 UNCHARACTERIZED
HYPOTHETICAL PROTEIN
(Parabacteroides
merdae) 		4 / 6 TYR A 231
GLY A 294
SER A 227
LEU A 226
 None
 1.07A 5bphD-4ei0A:
undetectable		 5bphD-4ei0A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 4ei0 UNCHARACTERIZED
HYPOTHETICAL PROTEIN
(Parabacteroides
merdae) 		4 / 7 LEU A 266
GLU A 297
ILE A 198
VAL A 326
 None
 1.03A 5jh7C-4ei0A:
undetectable		 5jh7C-4ei0A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_I_Z80I401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4ei0 UNCHARACTERIZED
HYPOTHETICAL PROTEIN
(Parabacteroides
merdae) 		4 / 9 ILE A 292
VAL A 303
THR A 253
ILE A 216
 None
 1.04A 5lg3I-4ei0A:
3.6		 5lg3I-4ei0A:
22.06