SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4eih'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_A_PPFA410_1
(PHOSPHONOACETATE
HYDROLASE)		 4eih ABELSON
TYROSINE-PROTEIN
KINASE 2
(Homo
sapiens) 		4 / 5 THR A 233
ASP A 253
HIS A 247
HIS A 248
 None
 1.25A 1ei6A-4eihA:
undetectable		 1ei6A-4eihA:
13.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PBC_A_BHAA396_0
(P-HYDROXYBENZOATE
HYDROXYLASE)		 4eih ABELSON
TYROSINE-PROTEIN
KINASE 2
(Homo
sapiens) 		5 / 10 VAL A 178
LEU A 196
LEU A 187
SER A 210
ALA A 182
 None
 1.24A 1pbcA-4eihA:
undetectable		 1pbcA-4eihA:
15.62