SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4eis'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K5Q_B_PACB559_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 4eis POLYSACCHARIDE
MONOOXYGENASE-3
(Neurospora
crassa) 		4 / 7 SER B  81
PRO B  79
ALA B 158
TYR B 171
 None
HIC  B   1 ( 3.7A)
None
HIC  B   1 (-3.5A)
 0.98A 1k5qA-4eisB:
undetectable
1k5qB-4eisB:
undetectable		 1k5qA-4eisB:
22.13
1k5qB-4eisB:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4eis POLYSACCHARIDE
MONOOXYGENASE-3
(Neurospora
crassa) 		4 / 6 GLY B  84
PRO B  85
ILE B 217
GLY B 117
 None
 0.85A 1usqB-4eisB:
undetectable		 1usqB-4eisB:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4eis POLYSACCHARIDE
MONOOXYGENASE-3
(Neurospora
crassa) 		4 / 6 GLY B  84
PRO B  85
ILE B 217
GLY B 117
 None
 0.85A 1usqC-4eisB:
undetectable		 1usqC-4eisB:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4eis POLYSACCHARIDE
MONOOXYGENASE-3
(Neurospora
crassa) 		4 / 6 GLY B  84
PRO B  85
ILE B 217
GLY B 117
 None
 0.84A 1usqD-4eisB:
undetectable		 1usqD-4eisB:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4eis POLYSACCHARIDE
MONOOXYGENASE-3
(Neurospora
crassa) 		4 / 6 GLY B  84
PRO B  85
ILE B 217
GLY B 117
 None
 0.84A 1usqE-4eisB:
undetectable		 1usqE-4eisB:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_F_CLMF1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4eis POLYSACCHARIDE
MONOOXYGENASE-3
(Neurospora
crassa) 		4 / 7 GLY B  84
PRO B  85
ILE B 217
GLY B 117
 None
 0.82A 1usqF-4eisB:
undetectable		 1usqF-4eisB:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_B_ACHB603_0
(ACETYLCHOLINESTERASE)		 4eis POLYSACCHARIDE
MONOOXYGENASE-3
(Neurospora
crassa) 		4 / 7 TYR B  89
GLU B 115
TYR B 215
GLY B 116
 None
 1.13A 2ha4B-4eisB:
undetectable		 2ha4B-4eisB:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_B_CLMB1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4eis POLYSACCHARIDE
MONOOXYGENASE-3
(Neurospora
crassa) 		4 / 6 GLY B  84
PRO B  85
ILE B 217
GLY B 117
 None
 0.85A 2jklB-4eisB:
undetectable		 2jklB-4eisB:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4eis POLYSACCHARIDE
MONOOXYGENASE-3
(Neurospora
crassa) 		4 / 7 GLY B  84
PRO B  85
ILE B 217
GLY B 117
 None
 0.85A 2jklE-4eisB:
undetectable		 2jklE-4eisB:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNC_A_CLUA808_1
(COPPER AMINE
OXIDASE, LIVER
ISOZYME)		 4eis POLYSACCHARIDE
MONOOXYGENASE-3
(Neurospora
crassa) 		4 / 7 ALA B 158
TYR B 171
MET B 131
HIS B 160
 None
HIC  B   1 (-3.5A)
None
None
 1.31A 2pncA-4eisB:
undetectable		 2pncA-4eisB:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA801_1
(PROSTAGLANDIN
REDUCTASE 1)		 4eis POLYSACCHARIDE
MONOOXYGENASE-3
(Neurospora
crassa) 		4 / 8 VAL B 205
SER B  81
TYR B 165
TYR B 171
 None
None
None
HIC  B   1 (-3.5A)
 1.00A 2y05A-4eisB:
undetectable
2y05B-4eisB:
undetectable		 2y05A-4eisB:
20.66
2y05B-4eisB:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3COT_A_STRA1501_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 4eis POLYSACCHARIDE
MONOOXYGENASE-3
(Neurospora
crassa) 		4 / 7 TYR B 198
GLU B 155
TYR B 215
TRP B 125
 None
 1.50A 3cotA-4eisB:
undetectable		 3cotA-4eisB:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OYA_A_RLTA398_1
(PFV INTEGRASE)		 4eis POLYSACCHARIDE
MONOOXYGENASE-3
(Neurospora
crassa) 		4 / 8 GLN B 169
PRO B  41
PRO B 172
GLU B 155
 HIC  B   1 ( 4.3A)
HIC  B   1 ( 4.6A)
None
None
 1.04A 3oyaA-4eisB:
undetectable		 3oyaA-4eisB:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_I_ACHI323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 4eis POLYSACCHARIDE
MONOOXYGENASE-3
(Neurospora
crassa) 		4 / 8 ILE B  87
GLU B 155
TYR B 198
PHE B 170
 None
 0.74A 3rqwI-4eisB:
undetectable
3rqwJ-4eisB:
undetectable		 3rqwI-4eisB:
21.82
3rqwJ-4eisB:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4eis POLYSACCHARIDE
MONOOXYGENASE-3
(Neurospora
crassa) 		4 / 7 ILE B  87
GLU B 155
TYR B 198
PHE B 170
 None
 0.80A 4a97H-4eisB:
undetectable		 4a97H-4eisB:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G10_A_ACTA301_0
(GLUTATHIONE
S-TRANSFERASE
HOMOLOG)		 4eis POLYSACCHARIDE
MONOOXYGENASE-3
(Neurospora
crassa) 		4 / 6 PRO B 218
ILE B  50
TYR B  89
PHE B 194
 None
 1.19A 4g10A-4eisB:
undetectable		 4g10A-4eisB:
22.46