SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4eiu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEA_A_ACAA90_1
(PLASMINOGEN)		 4eiu UNCHARACTERIZED
HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		4 / 8 ASP A 186
TRP A 260
TYR A 199
ARG A 202
 None
None
PEG  A 305 ( 4.5A)
None
 1.15A 1ceaA-4eiuA:
undetectable
1ceaB-4eiuA:
undetectable		 1ceaA-4eiuA:
14.46
1ceaB-4eiuA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEA_B_ACAB90_1
(PLASMINOGEN)		 4eiu UNCHARACTERIZED
HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		4 / 7 ASP A 186
TRP A 260
TYR A 199
ARG A 202
 None
None
PEG  A 305 ( 4.5A)
None
 1.15A 1ceaB-4eiuA:
undetectable		 1ceaB-4eiuA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_A_AMHA90_1
(PLASMINOGEN)		 4eiu UNCHARACTERIZED
HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		4 / 7 ASP A 186
TRP A 260
TYR A 199
ARG A 202
 None
None
PEG  A 305 ( 4.5A)
None
 1.11A 1cebA-4eiuA:
undetectable		 1cebA-4eiuA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_B_AMHB90_1
(PLASMINOGEN)		 4eiu UNCHARACTERIZED
HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		4 / 7 ASP A 186
TRP A 260
TYR A 199
ARG A 202
 None
None
PEG  A 305 ( 4.5A)
None
 1.25A 1cebB-4eiuA:
undetectable		 1cebB-4eiuA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_B_AMHB90_1
(PLASMINOGEN)		 4eiu UNCHARACTERIZED
HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		4 / 7 ASP A 186
TRP A 260
TYR A 199
ARG A 202
 None
None
PEG  A 305 ( 4.5A)
None
 1.39A 1cebB-4eiuA:
undetectable		 1cebB-4eiuA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4002_1
(SERUM ALBUMIN)		 4eiu UNCHARACTERIZED
HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		4 / 6 VAL A 191
VAL A 151
SER A 229
GLN A 228
 None
None
None
PEG  A 307 (-4.9A)
 1.12A 1e7aB-4eiuA:
undetectable		 1e7aB-4eiuA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 4eiu UNCHARACTERIZED
HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		5 / 11 VAL A  58
PHE A  75
GLY A  36
ILE A 123
LEU A  60
 None
 0.72A 1z11A-4eiuA:
undetectable		 1z11A-4eiuA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 4eiu UNCHARACTERIZED
HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		5 / 11 VAL A  58
PHE A  75
GLY A  36
ILE A 123
LEU A  60
 None
 0.73A 1z11B-4eiuA:
undetectable		 1z11B-4eiuA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXK_A_IMNA2001_1
(SERUM ALBUMIN)		 4eiu UNCHARACTERIZED
HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		4 / 8 SER A 216
ALA A 245
ARG A 246
LEU A 137
 None
None
PEG  A 305 (-3.2A)
None
 1.04A 2bxkA-4eiuA:
undetectable		 2bxkA-4eiuA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_D_CHDD702_0
(FERROCHELATASE)		 4eiu UNCHARACTERIZED
HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		3 / 3 ARG A  57
GLY A  99
PRO A 100
 None
 0.72A 2hreD-4eiuA:
undetectable		 2hreD-4eiuA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_A_SAMA201_1
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 4eiu UNCHARACTERIZED
HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		4 / 4 PRO A 103
ASP A  98
ASP A  74
ASP A 250
 None
 1.17A 2nyuA-4eiuA:
undetectable		 2nyuA-4eiuA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 4eiu UNCHARACTERIZED
HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		3 / 3 ASP A 250
TYR A 249
LYS A 178
 None
PEG  A 302 (-4.5A)
PEG  A 309 (-3.1A)
 1.08A 2othA-4eiuA:
undetectable		 2othA-4eiuA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_A_NCAA300_0
(PROTOGLOBIN)		 4eiu UNCHARACTERIZED
HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		4 / 7 VAL A  58
PHE A 131
VAL A 119
ILE A  88
 None
 0.94A 3zjqA-4eiuA:
undetectable		 3zjqA-4eiuA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_B_NCAB300_0
(PROTOGLOBIN)		 4eiu UNCHARACTERIZED
HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		4 / 7 VAL A  58
PHE A 131
VAL A 119
ILE A  88
 None
 0.98A 3zjqB-4eiuA:
undetectable		 3zjqB-4eiuA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 4eiu UNCHARACTERIZED
HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		5 / 12 VAL A  47
PHE A 136
ASN A 261
GLY A  99
GLY A 161
 None
None
None
None
PEG  A 304 ( 4.5A)
 1.11A 4pevB-4eiuA:
undetectable		 4pevB-4eiuA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QT3_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 4eiu UNCHARACTERIZED
HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		5 / 10 ASP A  74
GLU A  62
ILE A  34
ILE A  97
PHE A  75
 None
PEG  A 308 (-2.7A)
None
None
None
 1.36A 4qt3A-4eiuA:
undetectable		 4qt3A-4eiuA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_1
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)		 4eiu UNCHARACTERIZED
HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		5 / 12 THR A 251
VAL A 253
VAL A  47
GLN A 134
ILE A  97
 None
PEG  A 302 (-4.8A)
None
None
None
 1.13A 4s0vA-4eiuA:
undetectable		 4s0vA-4eiuA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MXT_A_K5YA1401_1
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 4eiu UNCHARACTERIZED
HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		3 / 3 ASP A  50
SER A 194
SER A 192
 None
 0.56A 6mxtA-4eiuA:
undetectable		 6mxtA-4eiuA:
19.75