SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ej1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_B_CFXB1002_2
(BETA-LACTAMASE
CTX-M-9)		 4ej1 NB113 CAMELID
ANTIBODY FRAGMENT
(Lama
glama) 		4 / 5 TYR C 107
PRO C 113
THR C  57
THR C  52
 None
 1.48A 1ymxB-4ej1C:
undetectable		 1ymxB-4ej1C:
22.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXT_B_MTXB2000_1
(ANTI-METHOTREXATE
CDR1-3 GRAFT VHH)		 4ej1 NB113 CAMELID
ANTIBODY FRAGMENT
(Lama
glama) 		6 / 12 LEU C   4
ALA C  24
MET C  34
ARG C  72
VAL C  79
ALA C  98
 None
 0.59A 3qxtB-4ej1C:
21.9		 3qxtB-4ej1C:
75.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_A_MTXA2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 4ej1 NB113 CAMELID
ANTIBODY FRAGMENT
(Lama
glama) 		5 / 12 MET C  34
ARG C  72
ASN C  74
VAL C  79
ALA C  98
 None
 0.34A 3qxvA-4ej1C:
21.6		 3qxvA-4ej1C:
74.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_C_MTXC2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 4ej1 NB113 CAMELID
ANTIBODY FRAGMENT
(Lama
glama) 		5 / 11 ALA C  24
MET C  34
ASN C  74
VAL C  79
ALA C  98
 None
 0.70A 3qxvC-4ej1C:
21.7		 3qxvC-4ej1C:
74.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_C_MTXC2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 4ej1 NB113 CAMELID
ANTIBODY FRAGMENT
(Lama
glama) 		5 / 11 MET C  34
ARG C  72
ASN C  74
VAL C  79
ALA C  98
 None
 0.38A 3qxvC-4ej1C:
21.7		 3qxvC-4ej1C:
74.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_E_MTXE2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 4ej1 NB113 CAMELID
ANTIBODY FRAGMENT
(Lama
glama) 		5 / 12 ALA C  97
SER C 101
ARG C  72
VAL C  79
ALA C  50
 None
 1.16A 3qxvE-4ej1C:
17.6		 3qxvE-4ej1C:
74.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CJK_B_ACTB302_0
(IMMUNOGLOBULIN FAB
HEAVY CHAIN)		 4ej1 NB113 CAMELID
ANTIBODY FRAGMENT
(Lama
glama) 		3 / 3 TYR C  60
GLY C  66
THR C  69
 None
 0.14A 6cjkB-4ej1C:
19.5		 6cjkB-4ej1C:
34.07