SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ejr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VL2_A_BEZA1162_0 (PEROXIREDOXIN-5)	4ejr	MAJOR CAPSID PROTEIN VP60 (Rabbit hemorrhagic disease virus)	5 / 10	PRO A 97 THR A 103 PHE A 221 THR A 181 GLY A 112	None	1.43A	2vl2A-4ejrA: undetectable 2vl2C-4ejrA: undetectable	2vl2A-4ejrA: 24.11 2vl2C-4ejrA: 24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WEK_B_DIFB1373_1 (ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2)	4ejr	MAJOR CAPSID PROTEIN VP60 (Rabbit hemorrhagic disease virus)	4 / 8	ASN A 99 VAL A 93 TYR A 74 PHE A 78	None	1.18A	2wekB-4ejrA: undetectable	2wekB-4ejrA: 20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3R9V_B_DXCB323_0 (INVASIN IPAD)	4ejr	MAJOR CAPSID PROTEIN VP60 (Rabbit hemorrhagic disease virus)	4 / 7	LEU A 173 ILE A 142 ILE A 144 VAL A 150	None	0.51A	3r9vA-4ejrA: undetectable 3r9vB-4ejrA: undetectable	3r9vA-4ejrA: 21.54 3r9vB-4ejrA: 21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CSY_B_ACRB601_2 (4-ALPHA-GLUCANOTRANS FERASE DPE1, CHLOROPLASTIC/AMYLOP LASTIC)	4ejr	MAJOR CAPSID PROTEIN VP60 (Rabbit hemorrhagic disease virus)	4 / 5	TYR A 73 PHE A 221 LEU A 106 PRO A 217	None	1.40A	5csyB-4ejrA: undetectable	5csyB-4ejrA: 19.46

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2VL2_A_BEZA1162_0","PEROXIREDOXIN-5","4ejr","MAJOR CAPSID PROTEIN VP60","Rabbit hemorrhagic disease virus",5,"PRO A  97;THR A 103;PHE A 221;THR A 181;GLY A 112","None","1.43A","2vl2A-4ejrA:undetectable;2vl2C-4ejrA:undetectable","2vl2A-4ejrA:24.11;2vl2C-4ejrA:24.11"],["2WEK_B_DIFB1373_1","ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2","4ejr","MAJOR CAPSID PROTEIN VP60","Rabbit hemorrhagic disease virus",4,"ASN A  99;VAL A  93;TYR A  74;PHE A  78","None","1.18A","2wekB-4ejrA:undetectable","2wekB-4ejrA:20.73"],["3R9V_B_DXCB323_0","INVASIN IPAD","4ejr","MAJOR CAPSID PROTEIN VP60","Rabbit hemorrhagic disease virus",4,"LEU A 173;ILE A 142;ILE A 144;VAL A 150","None","0.51A","3r9vA-4ejrA:undetectable;3r9vB-4ejrA:undetectable","3r9vA-4ejrA:21.54;3r9vB-4ejrA:21.54"],["5CSY_B_ACRB601_2","4-ALPHA-GLUCANOTRANSFERASE DPE1, CHLOROPLASTIC\/AMYLOPLASTIC","4ejr","MAJOR CAPSID PROTEIN VP60","Rabbit hemorrhagic disease virus",4,"TYR A  73;PHE A 221;LEU A 106;PRO A 217","None","1.40A","5csyB-4ejrA:undetectable","5csyB-4ejrA:19.46"]]