SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ejy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_A_017A200_2
(FIV PROTEASE)		 4ejy 3-METHYLADENINE DNA
GLYCOSYLASE
(Caldanaerobacter
subterraneus) 		5 / 10 LEU A 212
ALA A 186
VAL A 119
VAL A 226
LEU A 118
 None
 1.31A 3ogpB-4ejyA:
undetectable		 3ogpB-4ejyA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AN2_A_EUIA1382_1
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 4ejy 3-METHYLADENINE DNA
GLYCOSYLASE
(Caldanaerobacter
subterraneus) 		6 / 12 LEU A 212
LEU A 118
ILE A 195
ASP A 185
GLY A 217
VAL A 218
 None
None
None
None
NA  A 301 ( 4.9A)
NA  A 301 (-4.6A)
 1.47A 4an2A-4ejyA:
undetectable		 4an2A-4ejyA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_A_BQ1A1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 4ejy 3-METHYLADENINE DNA
GLYCOSYLASE
(Caldanaerobacter
subterraneus) 		3 / 3 GLU A  99
ALA A 100
PHE A 103
 None
 0.48A 4v1fA-4ejyA:
undetectable		 4v1fA-4ejyA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_C_BQ1C1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 4ejy 3-METHYLADENINE DNA
GLYCOSYLASE
(Caldanaerobacter
subterraneus) 		3 / 3 GLU A  99
ALA A 100
PHE A 103
 None
 0.51A 4v1fC-4ejyA:
undetectable		 4v1fC-4ejyA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MRA_B_DM2B204_1
(SORCIN)		 4ejy 3-METHYLADENINE DNA
GLYCOSYLASE
(Caldanaerobacter
subterraneus) 		4 / 6 TYR A  84
PHE A  20
ASP A  83
GLY A  85
 None
 1.24A 5mraA-4ejyA:
undetectable
5mraB-4ejyA:
undetectable		 5mraA-4ejyA:
19.69
5mraB-4ejyA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_E_PFLE406_1
(PROTON-GATED ION
CHANNEL)		 4ejy 3-METHYLADENINE DNA
GLYCOSYLASE
(Caldanaerobacter
subterraneus) 		5 / 10 TYR A 182
ILE A 122
ILE A 183
ILE A 132
ILE A 136
 None
 1.07A 5murE-4ejyA:
undetectable		 5murE-4ejyA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_1
(CYTOCHROME P450 3A4)		 4ejy 3-METHYLADENINE DNA
GLYCOSYLASE
(Caldanaerobacter
subterraneus) 		5 / 12 ASP A  48
PHE A 157
ALA A 180
ALA A 187
GLU A 162
 None
 1.02A 5vcgA-4ejyA:
undetectable		 5vcgA-4ejyA:
21.89