SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ekd'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WRL_E_TFPE212_1 (TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES)	4ekd	GUANINE NUCLEOTIDE-BINDING PROTEIN G(Q) SUBUNIT ALPHA (Mus musculus)	4 / 7	PHE A 272 LEU A 196 MET A 227 SER A 225	None	0.99A	1wrlE-4ekdA: undetectable	1wrlE-4ekdA: 14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YAJ_K_BEZK4387_0 (CES1 PROTEIN)	4ekd	GUANINE NUCLEOTIDE-BINDING PROTEIN G(Q) SUBUNIT ALPHA (Mus musculus)	3 / 3	TRP A 263 LEU A  43 LYS A  41	None	1.40A	1yajK-4ekdA: 2.6	1yajK-4ekdA: 21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2KUH_A_HLTA150_1 (CALMODULIN)	4ekd	GUANINE NUCLEOTIDE-BINDING PROTEIN G(Q) SUBUNIT ALPHA (Mus musculus)	4 / 6	LEU A  42 MET A 227 LEU A  44 MET A 203	None	1.24A	2kuhA-4ekdA: undetectable	2kuhA-4ekdA: 10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VDY_B_HCYB1384_1 (CORTICOSTEROID-BINDI NG GLOBULIN)	4ekd	GUANINE NUCLEOTIDE-BINDING PROTEIN G(Q) SUBUNIT ALPHA (Mus musculus)	5 / 12	VAL A 199 ILE A 348 ASN A 352 SER A 268 PHE A 201	None	1.42A	2vdyB-4ekdA: undetectable	2vdyB-4ekdA: 22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TYE_B_YTZB902_1 (DIHYDROPTEROATE SYNTHASE)	4ekd	GUANINE NUCLEOTIDE-BINDING PROTEIN G(Q) SUBUNIT ALPHA (Mus musculus)	3 / 3	PHE A 292 LYS A 252 SER A 251	None	1.32A	3tyeB-4ekdA: 2.3	3tyeB-4ekdA: 20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L3G_F_ACTF401_0 (METHYLAMINE DEHYDROGENASE HEAVY CHAIN)	4ekd	GUANINE NUCLEOTIDE-BINDING PROTEIN G(Q) SUBUNIT ALPHA (Mus musculus)	3 / 3	ARG A  38 LEU A  40 GLU A  39	None	0.67A	4l3gF-4ekdA: undetectable	4l3gF-4ekdA: 20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4N48_B_SAMB601_1 (CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-M ETHYLTRANSFERASE 1)	4ekd	GUANINE NUCLEOTIDE-BINDING PROTEIN G(Q) SUBUNIT ALPHA (Mus musculus)	4 / 5	ASN A 274 GLY A  51 ASP A 163 ASP A 155	GDP  A 401 (-3.5A) GDP  A 401 (-3.2A) None GDP  A 401 ( 4.8A)	1.10A	4n48B-4ekdA: undetectable	4n48B-4ekdA: 23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4N49_A_SAMA601_1 (CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-M ETHYLTRANSFERASE 1)	4ekd	GUANINE NUCLEOTIDE-BINDING PROTEIN G(Q) SUBUNIT ALPHA (Mus musculus)	4 / 4	ASN A 274 GLY A  51 ASP A 163 ASP A 155	GDP  A 401 (-3.5A) GDP  A 401 (-3.2A) None GDP  A 401 ( 4.8A)	1.09A	4n49A-4ekdA: undetectable	4n49A-4ekdA: 23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UCK_A_SAMA2409_0 (RNA-DIRECTED RNA POLYMERASE L)	4ekd	GUANINE NUCLEOTIDE-BINDING PROTEIN G(Q) SUBUNIT ALPHA (Mus musculus)	6 / 12	GLY A  51 GLY A  48 GLY A 208 SER A  50 ALA A 331 THR A 332	GDP  A 401 (-3.2A) ALF  A 402 (-2.9A) ALF  A 402 (-3.1A) GDP  A 401 (-3.9A) GDP  A 401 (-3.2A) GDP  A 401 (-3.6A)	1.41A	4uckA-4ekdA: undetectable	4uckA-4ekdA: 21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4X5F_A_FOLA201_0 (DIHYDROFOLATE REDUCTASE)	4ekd	GUANINE NUCLEOTIDE-BINDING PROTEIN G(Q) SUBUNIT ALPHA (Mus musculus)	5 / 12	ILE A 217 PHE A 220 THR A 257 ILE A 258 LEU A  45	None	1.08A	4x5fA-4ekdA: undetectable	4x5fA-4ekdA: 16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4X5F_B_FOLB201_0 (DIHYDROFOLATE REDUCTASE)	4ekd	GUANINE NUCLEOTIDE-BINDING PROTEIN G(Q) SUBUNIT ALPHA (Mus musculus)	5 / 12	ILE A 217 PHE A 220 THR A 257 ILE A 258 LEU A  45	None	1.10A	4x5fB-4ekdA: undetectable	4x5fB-4ekdA: 16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F6S_B_CXQB705_1 (ENVELOPE GLYCOPROTEIN,ENVELOP E GLYCOPROTEIN,GP1 ENVELOPE GLYCOPROTEIN)	4ekd	GUANINE NUCLEOTIDE-BINDING PROTEIN G(Q) SUBUNIT ALPHA (Mus musculus)	4 / 6	VAL A 199 LEU A  40 LEU A  42 LEU A 351	None	0.90A	6f6sA-4ekdA: undetectable 6f6sB-4ekdA: undetectable	6f6sA-4ekdA: 12.20 6f6sB-4ekdA: 13.13