SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4elz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMA_B_NCAB700_0
(EXOTOXIN A)		 4elz DNA GYRASE SUBUNIT A
(Aliivibrio
fischeri) 		4 / 6 GLY A 418
TYR A 448
ALA A 384
GLU A 381
 None
None
None
GOL  A 501 (-3.0A)
 1.01A 1dmaB-4elzA:
undetectable		 1dmaB-4elzA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFP_A_8W5A804_2
(GLUCOCORTICOID
RECEPTOR)		 4elz DNA GYRASE SUBUNIT A
(Aliivibrio
fischeri) 		4 / 4 LEU A 385
MET A 423
ILE A 390
LEU A 475
 None
 1.25A 5nfpA-4elzA:
undetectable		 5nfpA-4elzA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4elz DNA GYRASE SUBUNIT A
(Aliivibrio
fischeri) 		4 / 5 LEU A 380
ALA A 384
LEU A 387
LEU A 424
 None
 0.83A 5vkqA-4elzA:
3.5
5vkqD-4elzA:
3.5		 5vkqA-4elzA:
6.63
5vkqD-4elzA:
6.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4elz DNA GYRASE SUBUNIT A
(Aliivibrio
fischeri) 		4 / 5 LEU A 424
LEU A 380
ALA A 384
LEU A 387
 None
 0.86A 5vkqA-4elzA:
3.5
5vkqB-4elzA:
3.5		 5vkqA-4elzA:
6.63
5vkqB-4elzA:
6.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4elz DNA GYRASE SUBUNIT A
(Aliivibrio
fischeri) 		4 / 5 LEU A 424
LEU A 380
ALA A 384
LEU A 387
 None
 0.85A 5vkqC-4elzA:
3.5
5vkqD-4elzA:
3.5		 5vkqC-4elzA:
6.63
5vkqD-4elzA:
6.63