SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4em6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		4 / 7 VAL D 265
VAL D 241
LEU D 292
LEU D 100
 None
 0.87A 1cqpA-4em6D:
undetectable
1cqpB-4em6D:
2.2		 1cqpA-4em6D:
15.90
1cqpB-4em6D:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZ4_A_BEZA784_0
(MALT REGULATORY
PROTEIN)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		4 / 6 LEU D  43
LEU D 311
PRO D 312
MET D 314
 None
 1.11A 1hz4A-4em6D:
undetectable		 1hz4A-4em6D:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J7K_A_ACTA701_0
(HOLLIDAY JUNCTION
DNA HELICASE RUVB)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		4 / 4 GLY D 316
LEU D 315
GLY D 319
ARG D 491
 None
 1.33A 1j7kA-4em6D:
undetectable		 1j7kA-4em6D:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRJ_A_ADNA300_1
(ALPHA-TRICHOSANTHIN)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		4 / 8 ILE D 146
GLY D 136
ILE D 133
ARG D 257
 None
 0.90A 1mrjA-4em6D:
undetectable		 1mrjA-4em6D:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_A_SALA710_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		4 / 7 VAL D 279
LEU D 484
ALA D 167
LEU D 168
 None
 0.75A 1pthA-4em6D:
0.0		 1pthA-4em6D:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_B_SALB711_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		4 / 7 VAL D 279
LEU D 484
ALA D 167
LEU D 168
 None
 0.75A 1pthB-4em6D:
undetectable		 1pthB-4em6D:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_A_SAMA500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		4 / 7 ASP D  51
PHE D  38
PHE D  31
SER D 427
 None
 1.25A 1rqpB-4em6D:
undetectable		 1rqpB-4em6D:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_C_SAMC500_0
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		4 / 8 ASP D  51
PHE D  38
PHE D  31
SER D 427
 None
 1.19A 1rqpA-4em6D:
undetectable		 1rqpA-4em6D:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		4 / 8 GLN D 349
ILE D 275
VAL D 271
PRO D 161
 None
 0.87A 1rxcB-4em6D:
undetectable		 1rxcB-4em6D:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_C_URFC2081_1
(URIDINE
PHOSPHORYLASE)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		4 / 7 GLN D 349
ILE D 275
VAL D 271
PRO D 161
 None
 0.90A 1rxcC-4em6D:
undetectable		 1rxcC-4em6D:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_D_URFD2021_1
(URIDINE
PHOSPHORYLASE)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		4 / 7 GLN D 349
ILE D 275
VAL D 271
PRO D 161
 None
 0.90A 1rxcD-4em6D:
undetectable		 1rxcD-4em6D:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_E_URFE2031_1
(URIDINE
PHOSPHORYLASE)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		4 / 8 GLN D 349
ILE D 275
VAL D 271
PRO D 161
 None
 0.93A 1rxcE-4em6D:
undetectable		 1rxcE-4em6D:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		4 / 7 GLN D 349
ILE D 275
VAL D 271
PRO D 161
 None
 0.89A 1rxcF-4em6D:
3.0		 1rxcF-4em6D:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_I_URFI2041_1
(URIDINE
PHOSPHORYLASE)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		4 / 8 GLN D 349
ILE D 275
VAL D 271
PRO D 161
 None
 0.93A 1rxcI-4em6D:
undetectable		 1rxcI-4em6D:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_K_URFK2061_1
(URIDINE
PHOSPHORYLASE)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		4 / 8 GLN D 349
ILE D 275
VAL D 271
PRO D 161
 None
 0.86A 1rxcK-4em6D:
undetectable		 1rxcK-4em6D:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		4 / 7 GLN D 349
ILE D 275
VAL D 271
PRO D 161
 None
 0.90A 1rxcL-4em6D:
undetectable		 1rxcL-4em6D:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S1U_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		5 / 10 ILE D 485
VAL D 271
TYR D 269
GLY D 160
LEU D 347
 None
 1.19A 1s1uA-4em6D:
undetectable		 1s1uA-4em6D:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_A_CHDA459_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		4 / 6 ASP D 337
VAL D 403
ILE D 472
TYR D 171
 None
 0.99A 1s9qA-4em6D:
undetectable		 1s9qA-4em6D:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_A_ACTA544_0
(ACETYLCHOLINESTERASE)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		5 / 8 GLY D 482
ALA D 486
ALA D 295
TRP D 272
PHE D 291
 None
 1.47A 2ha4A-4em6D:
undetectable		 2ha4A-4em6D:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HJH_A_NCAA900_0
(NAD-DEPENDENT
HISTONE DEACETYLASE
SIR2)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		4 / 5 ILE D 253
PRO D 254
PHE D 129
ILE D 203
 None
 1.10A 2hjhA-4em6D:
undetectable		 2hjhA-4em6D:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_1
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		5 / 12 ALA D 236
ALA D 221
ALA D 218
ILE D 253
LEU D 277
 None
 1.14A 2nyrA-4em6D:
3.8		 2nyrA-4em6D:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_A_SAMA1299_0
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		4 / 8 ASP D  51
PHE D  38
PHE D  31
SER D 427
 None
 1.18A 2v7uA-4em6D:
undetectable		 2v7uA-4em6D:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_B_SAMB1299_1
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		4 / 7 ASP D  51
PHE D  38
PHE D  31
SER D 427
 None
 1.22A 2v7uB-4em6D:
undetectable		 2v7uB-4em6D:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_2
(BETA-1 ADRENERGIC
RECEPTOR)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		3 / 3 VAL D  95
ASN D 502
TRP D 507
 None
 0.84A 2y00B-4em6D:
undetectable		 2y00B-4em6D:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_A_ADNA401_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		5 / 10 TYR D 171
PHE D 291
ALA D 282
VAL D 271
LEU D 481
 None
 1.20A 3ay0A-4em6D:
undetectable		 3ay0A-4em6D:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_B_SAMB270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		5 / 11 ALA D 205
GLY D 160
ILE D 203
LEU D 277
VAL D 279
 None
 1.12A 3gyqB-4em6D:
undetectable		 3gyqB-4em6D:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA277_0
(UNIVERSAL STRESS
PROTEIN)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		3 / 3 ASP D 102
SER D 105
ARG D 303
 None
 0.58A 3loqA-4em6D:
3.5		 3loqA-4em6D:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		5 / 12 ALA D 130
GLY D 276
ILE D 203
ASP D 158
VAL D 279
 None
 1.11A 3o7wA-4em6D:
3.5		 3o7wA-4em6D:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD2_1
(CYTOCHROME P450 2D6)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		5 / 9 PHE D 129
LEU D 201
THR D 200
LEU D 277
ILE D 281
 None
 1.06A 3tbgD-4em6D:
undetectable		 3tbgD-4em6D:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		5 / 12 VAL D 122
PHE D 288
ILE D 485
VAL D 265
VAL D 119
 None
 1.05A 3w68D-4em6D:
undetectable		 3w68D-4em6D:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_I_ZPCI1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		4 / 6 GLU D 400
ILE D 333
HIS D 490
VAL D  74
 None
 1.17A 4a97I-4em6D:
2.2		 4a97I-4em6D:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_A_URFA1301_1
(URIDINE
PHOSPHORYLASE)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		4 / 8 GLN D 349
ILE D 275
VAL D 271
PRO D 161
 None
 0.84A 4e1vA-4em6D:
2.6		 4e1vA-4em6D:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_B_URFB1301_1
(URIDINE
PHOSPHORYLASE)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		4 / 7 GLN D 349
ILE D 275
VAL D 271
PRO D 161
 None
 0.87A 4e1vB-4em6D:
undetectable		 4e1vB-4em6D:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_C_URFC1301_1
(URIDINE
PHOSPHORYLASE)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		4 / 8 GLN D 349
ILE D 275
VAL D 271
PRO D 161
 None
 0.86A 4e1vC-4em6D:
undetectable		 4e1vC-4em6D:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_D_URFD1301_1
(URIDINE
PHOSPHORYLASE)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		4 / 8 GLN D 349
ILE D 275
VAL D 271
PRO D 161
 None
 0.90A 4e1vD-4em6D:
undetectable		 4e1vD-4em6D:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		4 / 8 GLN D 349
ILE D 275
VAL D 271
PRO D 161
 None
 0.90A 4e1vE-4em6D:
2.7		 4e1vE-4em6D:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_G_URFG1301_1
(URIDINE
PHOSPHORYLASE)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		4 / 8 GLN D 349
ILE D 275
VAL D 271
PRO D 161
 None
 0.88A 4e1vG-4em6D:
undetectable		 4e1vG-4em6D:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_H_URFH1301_1
(URIDINE
PHOSPHORYLASE)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		4 / 8 GLN D 349
ILE D 275
VAL D 271
PRO D 161
 None
 0.89A 4e1vH-4em6D:
undetectable		 4e1vH-4em6D:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ENH_A_FVXA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		5 / 12 LEU D 201
ILE D 133
ALA D 130
GLY D 260
ALA D 239
 None
 1.09A 4enhA-4em6D:
undetectable		 4enhA-4em6D:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_1
(METHYLTRANSFERASE
NSUN4)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		3 / 3 ASP D 131
ARG D 134
ASP D 124
 None
 0.79A 4fp9C-4em6D:
undetectable		 4fp9C-4em6D:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_1
(METHYLTRANSFERASE
NSUN4)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		3 / 3 ASP D 131
ARG D 134
ASP D 124
 None
 0.76A 4fp9F-4em6D:
undetectable		 4fp9F-4em6D:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_A_ACTA708_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		3 / 3 GLY D 266
GLY D 267
GLN D 506
 None
 0.38A 5imsA-4em6D:
2.8		 5imsA-4em6D:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		5 / 12 ARG D   3
LEU D 317
VAL D  74
ALA D  72
LEU D   8
 None
 0.95A 5jw1B-4em6D:
undetectable		 5jw1B-4em6D:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_1
(ADENOSINE KINASE)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		5 / 12 LEU D 476
GLY D 160
ALA D 167
LEU D 340
GLY D 276
 None
 0.99A 5kb5A-4em6D:
2.5		 5kb5A-4em6D:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		5 / 12 ILE D 253
GLY D 235
HIS D 237
ALA D 239
PHE D 129
 None
 1.06A 5n0oB-4em6D:
2.1		 5n0oB-4em6D:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		5 / 12 ILE D 253
GLY D 235
HIS D 237
ALA D 239
PHE D 129
 None
 1.01A 5n0tB-4em6D:
undetectable		 5n0tB-4em6D:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0C_D_TA1D502_1
(TUBULIN BETA CHAIN)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		5 / 12 VAL D 374
LEU D 343
LEU D 484
GLY D 316
LEU D 315
 None
 0.98A 6b0cD-4em6D:
undetectable		 6b0cD-4em6D:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		4 / 6 SER D 157
ALA D 274
SER D 273
ALA D 205
 None
 0.82A 6bocA-4em6D:
undetectable
6bocB-4em6D:
undetectable
6bocC-4em6D:
undetectable
6bocD-4em6D:
undetectable		 6bocA-4em6D:
4.09
6bocB-4em6D:
4.09
6bocC-4em6D:
4.09
6bocD-4em6D:
4.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FK2_A_SORA302_0
(GALECTIN-3)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		4 / 4 ARG D 331
GLU D 400
GLU D 495
ARG D 491
 None
 1.08A 6fk2A-4em6D:
undetectable		 6fk2A-4em6D:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FK2_A_SORA302_0
(GALECTIN-3)		 4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		4 / 4 ARG D 491
GLU D 495
GLU D 400
ARG D 331
 None
 1.07A 6fk2A-4em6D:
undetectable		 6fk2A-4em6D:
12.14