SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4emy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9H_A_RAPA108_1
(FKBP12.6)		 4emy AMINOTRANSFERASE
CLASS I AND II
(Anaerococcus
prevotii) 		5 / 12 VAL A 250
ILE A 273
PHE A 241
VAL A  85
ILE A  86
 None
 0.96A 1c9hA-4emyA:
undetectable		 1c9hA-4emyA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXH_B_PACB1001_0
(PENICILLIN ACYLASE)		 4emy AMINOTRANSFERASE
CLASS I AND II
(Anaerococcus
prevotii) 		4 / 7 PHE A 249
SER A 100
ALA A 270
ILE A 102
 None
 0.83A 1fxhA-4emyA:
undetectable
1fxhB-4emyA:
undetectable		 1fxhA-4emyA:
22.08
1fxhB-4emyA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 4emy AMINOTRANSFERASE
CLASS I AND II
(Anaerococcus
prevotii) 		4 / 8 SER A 179
ASP A 195
PHE A 158
LEU A 218
 None
 1.08A 1lhvA-4emyA:
undetectable		 1lhvA-4emyA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PNL_B_PACB559_0
(PENICILLIN
AMIDOHYDROLASE)		 4emy AMINOTRANSFERASE
CLASS I AND II
(Anaerococcus
prevotii) 		4 / 8 PHE A 249
SER A 100
ALA A 270
ILE A 102
 None
 0.94A 1pnlA-4emyA:
undetectable
1pnlB-4emyA:
undetectable		 1pnlA-4emyA:
22.08
1pnlB-4emyA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 4emy AMINOTRANSFERASE
CLASS I AND II
(Anaerococcus
prevotii) 		3 / 3 GLY A 231
GLU A 226
ASP A 232
 None
 0.57A 2b25B-4emyA:
2.3		 2b25B-4emyA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_B_CHDB701_0
(FERROCHELATASE)		 4emy AMINOTRANSFERASE
CLASS I AND II
(Anaerococcus
prevotii) 		3 / 3 LYS A 315
GLY A  91
PRO A  92
 None
 0.83A 2hreB-4emyA:
2.0		 2hreB-4emyA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		 4emy AMINOTRANSFERASE
CLASS I AND II
(Anaerococcus
prevotii) 		3 / 3 TYR A 191
GLY A 185
PHE A 351
 None
 0.66A 2m2pB-4emyA:
undetectable		 2m2pB-4emyA:
4.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1003_0
(ALDEHYDE
DEHYDROGENASE A)		 4emy AMINOTRANSFERASE
CLASS I AND II
(Anaerococcus
prevotii) 		4 / 5 ILE A 102
LEU A 287
ALA A 101
PHE A 249
 None
 1.05A 2opxA-4emyA:
undetectable		 2opxA-4emyA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_B_BRLB2_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 4emy AMINOTRANSFERASE
CLASS I AND II
(Anaerococcus
prevotii) 		5 / 12 LEU A  89
VAL A 252
HIS A 260
LEU A 322
TYR A 318
 None
 1.39A 2prgB-4emyA:
undetectable		 2prgB-4emyA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_0
(WNT INHIBITORY
FACTOR 1)		 4emy AMINOTRANSFERASE
CLASS I AND II
(Anaerococcus
prevotii) 		5 / 12 ILE A 375
LEU A 403
ILE A  37
ARG A 332
ILE A 358
 None
 1.12A 2ygnA-4emyA:
undetectable		 2ygnA-4emyA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA601_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 4emy AMINOTRANSFERASE
CLASS I AND II
(Anaerococcus
prevotii) 		4 / 7 ALA A 269
ALA A 110
VAL A  85
ILE A  99
 None
 0.79A 3a2qA-4emyA:
undetectable		 3a2qA-4emyA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 4emy AMINOTRANSFERASE
CLASS I AND II
(Anaerococcus
prevotii) 		4 / 4 SER A 267
GLY A 268
GLY A 298
GLY A  77
 None
 0.79A 3bogB-4emyA:
undetectable
3bogD-4emyA:
undetectable		 3bogB-4emyA:
undetectable
3bogD-4emyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HBB_A_TMQA611_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4emy AMINOTRANSFERASE
CLASS I AND II
(Anaerococcus
prevotii) 		5 / 10 ALA A  24
ILE A  20
ILE A 384
LEU A 403
ILE A 375
 None
 1.10A 3hbbA-4emyA:
2.2		 3hbbA-4emyA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 4emy AMINOTRANSFERASE
CLASS I AND II
(Anaerococcus
prevotii) 		3 / 3 ASP A 213
LYS A 212
ASP A 211
 None
 0.75A 4a7tA-4emyA:
undetectable		 4a7tA-4emyA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DU2_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT B7)		 4emy AMINOTRANSFERASE
CLASS I AND II
(Anaerococcus
prevotii) 		4 / 7 ALA A 103
ALA A 302
ALA A  73
PRO A  74
 None
 0.76A 4du2A-4emyA:
undetectable		 4du2A-4emyA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DU2_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT B7)		 4emy AMINOTRANSFERASE
CLASS I AND II
(Anaerococcus
prevotii) 		4 / 7 ALA A 103
ALA A 302
ALA A  73
PRO A  74
 None
 0.70A 4du2B-4emyA:
undetectable		 4du2B-4emyA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_A_ACTA1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 4emy AMINOTRANSFERASE
CLASS I AND II
(Anaerococcus
prevotii) 		4 / 5 GLY A 109
ALA A 110
GLY A 106
PRO A 105
 None
None
PLP  A 501 (-3.2A)
None
 0.90A 4u9uA-4emyA:
undetectable		 4u9uA-4emyA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_B_ACTB1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 4emy AMINOTRANSFERASE
CLASS I AND II
(Anaerococcus
prevotii) 		4 / 5 GLY A 109
ALA A 110
GLY A 106
PRO A 105
 None
None
PLP  A 501 (-3.2A)
None
 0.94A 4u9uB-4emyA:
undetectable		 4u9uB-4emyA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_A_CL6A502_1
(CYTOCHROME P-450)		 4emy AMINOTRANSFERASE
CLASS I AND II
(Anaerococcus
prevotii) 		4 / 5 LEU A 399
ALA A 404
THR A 407
ILE A 366
 None
 0.92A 4xe3A-4emyA:
undetectable		 4xe3A-4emyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_B_CL6B502_1
(CYTOCHROME P-450)		 4emy AMINOTRANSFERASE
CLASS I AND II
(Anaerococcus
prevotii) 		4 / 5 LEU A 399
ALA A 404
THR A 407
ILE A 366
 None
 0.96A 4xe3B-4emyA:
undetectable		 4xe3B-4emyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HKG_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1B)		 4emy AMINOTRANSFERASE
CLASS I AND II
(Anaerococcus
prevotii) 		5 / 12 VAL A 250
ILE A 273
PHE A 241
VAL A  85
ILE A  86
 None
 0.97A 5hkgA-4emyA:
undetectable		 5hkgA-4emyA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_1
(CYTOCHROME P450 3A4)		 4emy AMINOTRANSFERASE
CLASS I AND II
(Anaerococcus
prevotii) 		5 / 12 PHE A  90
ILE A  86
ALA A 270
ALA A 223
GLU A 226
 None
None
None
PLP  A 501 ( 4.1A)
None
 1.22A 5vcgA-4emyA:
0.4		 5vcgA-4emyA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 4emy AMINOTRANSFERASE
CLASS I AND II
(Anaerococcus
prevotii) 		3 / 3 ARG A 385
PHE A 376
LEU A  41
 None
 0.91A 5x1bC-4emyA:
undetectable		 5x1bC-4emyA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_A_ADNA506_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 4emy AMINOTRANSFERASE
CLASS I AND II
(Anaerococcus
prevotii) 		4 / 6 LEU A  54
LYS A 315
GLU A 319
LEU A 322
 None
 1.38A 5xooA-4emyA:
undetectable		 5xooA-4emyA:
13.01