SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4eo0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DDR_A_MTXA200_1 (DIHYDROFOLATE REDUCTASE)	4eo0	ATTACHMENT PROTEIN G3P (Salmonella virus IKe)	5 / 12	ALA A 51 THR A 7 SER A 5 ILE A 6 LEU A 62	None	0.97A	1ddrA-4eo0A: undetectable	1ddrA-4eo0A: 21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RG7_A_MTXA161_1 (DIHYDROFOLATE REDUCTASE)	4eo0	ATTACHMENT PROTEIN G3P (Salmonella virus IKe)	5 / 12	ALA A 51 THR A 7 SER A 5 ILE A 6 LEU A 62	None	1.01A	1rg7A-4eo0A: undetectable	1rg7A-4eo0A: 21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DFR_A_MTXA161_1 (DIHYDROFOLATE REDUCTASE)	4eo0	ATTACHMENT PROTEIN G3P (Salmonella virus IKe)	5 / 12	ALA A 51 THR A 7 SER A 5 ILE A 6 LEU A 62	None	1.03A	4dfrA-4eo0A: undetectable	4dfrA-4eo0A: 21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LAK_J_BEZJ1_0 (3CL PROTEASE BEZ-TYR-TYR-ASN-ECC PEPTIDE INHIBITOR)	4eo0	ATTACHMENT PROTEIN G3P (Salmonella virus IKe)	3 / 3	SER A 9 TYR A 10 TYR A 11	None	0.90A	5lakC-4eo0A: undetectable 5lakJ-4eo0A: undetectable	5lakC-4eo0A: 14.01 5lakJ-4eo0A: 6.90

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DDR_A_MTXA200_1","DIHYDROFOLATE REDUCTASE","4eo0","ATTACHMENT PROTEIN G3P","Salmonella virus IKe",5,"ALA A  51;THR A   7;SER A   5;ILE A   6;LEU A  62","None","0.97A","1ddrA-4eo0A:undetectable","1ddrA-4eo0A:21.66"],["1RG7_A_MTXA161_1","DIHYDROFOLATE REDUCTASE","4eo0","ATTACHMENT PROTEIN G3P","Salmonella virus IKe",5,"ALA A  51;THR A   7;SER A   5;ILE A   6;LEU A  62","None","1.01A","1rg7A-4eo0A:undetectable","1rg7A-4eo0A:21.66"],["4DFR_A_MTXA161_1","DIHYDROFOLATE REDUCTASE","4eo0","ATTACHMENT PROTEIN G3P","Salmonella virus IKe",5,"ALA A  51;THR A   7;SER A   5;ILE A   6;LEU A  62","None","1.03A","4dfrA-4eo0A:undetectable","4dfrA-4eo0A:21.66"],["5LAK_J_BEZJ1_0","3CL PROTEASE;BEZ-TYR-TYR-ASN-ECC PEPTIDE INHIBITOR","4eo0","ATTACHMENT PROTEIN G3P","Salmonella virus IKe",3,"SER A   9;TYR A  10;TYR A  11","None","0.90A","5lakC-4eo0A:undetectable;5lakJ-4eo0A:undetectable","5lakC-4eo0A:14.01;5lakJ-4eo0A:6.90"]]