SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4eo3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)		 4eo3 BACTERIOFERRITIN
COMIGRATORY
PROTEIN/NADH
DEHYDROGENASE
(Thermotoga
maritima) 		4 / 8 PRO A  33
THR A  37
GLY A  39
ARG A 103
 None
SO4  A 402 (-3.4A)
SO4  A 402 (-3.3A)
SO4  A 402 (-3.5A)
 0.48A 1h4oB-4eo3A:
18.0		 1h4oB-4eo3A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_G_BEZG1162_0
(PEROXIREDOXIN 5)		 4eo3 BACTERIOFERRITIN
COMIGRATORY
PROTEIN/NADH
DEHYDROGENASE
(Thermotoga
maritima) 		4 / 8 PRO A  33
THR A  37
GLY A  39
ARG A 103
 None
SO4  A 402 (-3.4A)
SO4  A 402 (-3.3A)
SO4  A 402 (-3.5A)
 0.40A 1h4oG-4eo3A:
17.8		 1h4oG-4eo3A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)		 4eo3 BACTERIOFERRITIN
COMIGRATORY
PROTEIN/NADH
DEHYDROGENASE
(Thermotoga
maritima) 		4 / 8 PRO A  33
THR A  37
GLY A  39
ARG A 103
 None
SO4  A 402 (-3.4A)
SO4  A 402 (-3.3A)
SO4  A 402 (-3.5A)
 0.46A 1oc3A-4eo3A:
17.8		 1oc3A-4eo3A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_B_FUAB703_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4eo3 BACTERIOFERRITIN
COMIGRATORY
PROTEIN/NADH
DEHYDROGENASE
(Thermotoga
maritima) 		3 / 3 VAL A 245
ALA A 244
HIS A 175
 None
 0.75A 1q23C-4eo3A:
undetectable		 1q23C-4eo3A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_G_FUAG708_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4eo3 BACTERIOFERRITIN
COMIGRATORY
PROTEIN/NADH
DEHYDROGENASE
(Thermotoga
maritima) 		3 / 3 VAL A 245
ALA A 244
HIS A 175
 None
 0.65A 1q23H-4eo3A:
undetectable		 1q23H-4eo3A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4eo3 BACTERIOFERRITIN
COMIGRATORY
PROTEIN/NADH
DEHYDROGENASE
(Thermotoga
maritima) 		3 / 3 VAL A 245
ALA A 244
HIS A 175
 None
 0.68A 1q23G-4eo3A:
undetectable		 1q23G-4eo3A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4eo3 BACTERIOFERRITIN
COMIGRATORY
PROTEIN/NADH
DEHYDROGENASE
(Thermotoga
maritima) 		3 / 3 VAL A 245
ALA A 244
HIS A 175
 None
 0.61A 1q23J-4eo3A:
undetectable		 1q23J-4eo3A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1URM_A_BEZA201_0
(PEROXIREDOXIN 5)		 4eo3 BACTERIOFERRITIN
COMIGRATORY
PROTEIN/NADH
DEHYDROGENASE
(Thermotoga
maritima) 		5 / 9 PRO A  33
THR A  37
GLY A  39
SER A  40
ARG A 103
 None
SO4  A 402 (-3.4A)
SO4  A 402 (-3.3A)
SO4  A 402 (-3.6A)
SO4  A 402 (-3.5A)
 0.54A 1urmA-4eo3A:
17.4		 1urmA-4eo3A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_C_BEZC1222_0
(PEROXIREDOXIN 6)		 4eo3 BACTERIOFERRITIN
COMIGRATORY
PROTEIN/NADH
DEHYDROGENASE
(Thermotoga
maritima) 		4 / 8 PRO A  33
THR A  37
SER A  40
ARG A 103
 None
SO4  A 402 (-3.4A)
SO4  A 402 (-3.6A)
SO4  A 402 (-3.5A)
 0.35A 2v32C-4eo3A:
16.7
2v32D-4eo3A:
19.0		 2v32C-4eo3A:
20.88
2v32D-4eo3A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_C_BEZC1218_0
(PEROXIREDOXIN 6.)		 4eo3 BACTERIOFERRITIN
COMIGRATORY
PROTEIN/NADH
DEHYDROGENASE
(Thermotoga
maritima) 		4 / 8 PRO A  33
THR A  37
SER A  40
ARG A 103
 None
SO4  A 402 (-3.4A)
SO4  A 402 (-3.6A)
SO4  A 402 (-3.5A)
 0.44A 2v41C-4eo3A:
19.1
2v41D-4eo3A:
19.1		 2v41C-4eo3A:
20.88
2v41D-4eo3A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_D_BEZD1222_0
(PEROXIREDOXIN 6.)		 4eo3 BACTERIOFERRITIN
COMIGRATORY
PROTEIN/NADH
DEHYDROGENASE
(Thermotoga
maritima) 		4 / 8 PRO A  33
THR A  37
SER A  40
ARG A 103
 None
SO4  A 402 (-3.4A)
SO4  A 402 (-3.6A)
SO4  A 402 (-3.5A)
 0.35A 2v41C-4eo3A:
19.1
2v41D-4eo3A:
19.1		 2v41C-4eo3A:
20.88
2v41D-4eo3A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_H_BEZH1222_0
(PEROXIREDOXIN 6.)		 4eo3 BACTERIOFERRITIN
COMIGRATORY
PROTEIN/NADH
DEHYDROGENASE
(Thermotoga
maritima) 		4 / 8 PRO A  33
THR A  37
SER A  40
ARG A 103
 None
SO4  A 402 (-3.4A)
SO4  A 402 (-3.6A)
SO4  A 402 (-3.5A)
 0.36A 2v41G-4eo3A:
16.6
2v41H-4eo3A:
16.7		 2v41G-4eo3A:
20.88
2v41H-4eo3A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 4eo3 BACTERIOFERRITIN
COMIGRATORY
PROTEIN/NADH
DEHYDROGENASE
(Thermotoga
maritima) 		4 / 4 GLY A 112
LEU A 134
PHE A  52
ILE A  28
 None
 0.95A 4xv2A-4eo3A:
1.9		 4xv2A-4eo3A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPR_A_PAUA404_0
(PANTOTHENATE KINASE
3)		 4eo3 BACTERIOFERRITIN
COMIGRATORY
PROTEIN/NADH
DEHYDROGENASE
(Thermotoga
maritima) 		4 / 5 GLY A  36
SER A  40
ARG A 103
GLY A  39
 None
SO4  A 402 (-3.6A)
SO4  A 402 (-3.5A)
SO4  A 402 (-3.3A)
 1.14A 5kprA-4eo3A:
undetectable		 5kprA-4eo3A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 4eo3 BACTERIOFERRITIN
COMIGRATORY
PROTEIN/NADH
DEHYDROGENASE
(Thermotoga
maritima) 		4 / 4 GLN A 254
THR A 253
LEU A 167
LEU A 170
 None
 1.26A 5m5kB-4eo3A:
3.0		 5m5kB-4eo3A:
21.50