SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4eog'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA8_0
(ACTINOMYCIN D)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		3 / 3 THR A 174
THR A 176
PRO A 173
 None
 0.80A 1a7yA-4eogA:
undetectable		 1a7yA-4eogA:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB8_0
(ACTINOMYCIN D)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		3 / 3 THR A 174
THR A 176
PRO A 173
 None
 0.80A 1a7yB-4eogA:
undetectable		 1a7yB-4eogA:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DF7_A_MTXA501_2
(DIHYDROFOLATE
REDUCTASE)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		3 / 3 TRP A  10
ARG A 212
THR A  33
 None
 1.00A 1df7A-4eogA:
1.3		 1df7A-4eogA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC8_0
(ACTINOMYCIN D)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		3 / 3 THR A 174
THR A 176
PRO A 173
 None
 0.79A 1dscC-4eogA:
undetectable		 1dscC-4eogA:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		5 / 11 PHE A 341
ILE A 347
LEU A 344
LEU A 190
LEU A 310
 None
 0.97A 1dtlA-4eogA:
undetectable		 1dtlA-4eogA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ9_A_CAMA503_0
(CYTOCHROME P450-CAM)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		4 / 8 THR A   8
LEU A   6
VAL A  38
VAL A  94
 None
 1.16A 1dz9A-4eogA:
undetectable		 1dz9A-4eogA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_0
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		4 / 4 THR A 176
LEU A 180
LEU A 159
GLN A 156
 None
 1.15A 1fbmA-4eogA:
undetectable		 1fbmA-4eogA:
6.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		3 / 3 THR A 174
THR A 176
PRO A 173
 None
 0.88A 1fjaC-4eogA:
undetectable		 1fjaC-4eogA:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		3 / 3 THR A 174
THR A 176
PRO A 173
 None
 0.88A 1fjaD-4eogA:
undetectable		 1fjaD-4eogA:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_C_CCSC47_0
(GLUTATHIONE
S-TRANSFERASE)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		4 / 6 TRP A  16
THR A   8
LEU A 165
GLY A 168
 None
 1.28A 1gtiC-4eogA:
undetectable		 1gtiC-4eogA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE2_0
(ACTINOMYCIN D)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		3 / 3 THR A 176
PRO A 173
THR A 174
 None
 0.82A 1i3wE-4eogA:
undetectable		 1i3wE-4eogA:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		3 / 3 THR A 174
THR A 176
PRO A 173
 None
 0.84A 1i3wE-4eogA:
undetectable		 1i3wE-4eogA:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_F_DVAF8_0
(ACTINOMYCIN D)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		3 / 3 THR A 174
THR A 176
PRO A 173
 None
 0.83A 1i3wF-4eogA:
undetectable		 1i3wF-4eogA:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		3 / 3 THR A 176
PRO A 173
THR A 174
 None
 0.84A 1i3wG-4eogA:
undetectable		 1i3wG-4eogA:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		3 / 3 THR A 174
THR A 176
PRO A 173
 None
 0.84A 1i3wG-4eogA:
undetectable		 1i3wG-4eogA:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		3 / 3 THR A 174
THR A 176
PRO A 173
 None
 0.82A 1i3wH-4eogA:
undetectable		 1i3wH-4eogA:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD2_0
(ACTINOMYCIN D)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		3 / 3 THR A 176
PRO A 173
THR A 174
 None
 0.83A 1mnvD-4eogA:
undetectable		 1mnvD-4eogA:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD8_0
(ACTINOMYCIN D)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		3 / 3 THR A 174
THR A 176
PRO A 173
 None
 0.81A 1mnvD-4eogA:
undetectable		 1mnvD-4eogA:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_B_CAMB1420_0
(CYTOCHROME P450-CAM)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		4 / 8 THR A   8
LEU A   6
VAL A  38
VAL A  94
 None
 1.15A 1o76B-4eogA:
undetectable		 1o76B-4eogA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OVF_B_DVAB2_0
(ACTINOMYCIN D)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		3 / 3 THR A 176
PRO A 173
THR A 174
 None
 0.85A 1ovfB-4eogA:
undetectable		 1ovfB-4eogA:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_A_DVAA8_0
(ACTINOMYCIN X2)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		3 / 3 THR A 174
THR A 176
PRO A 173
 None
 0.81A 1qfiA-4eogA:
undetectable		 1qfiA-4eogA:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_B_DVAB8_0
(ACTINOMYCIN X2)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		3 / 3 THR A 174
THR A 176
PRO A 173
 None
 0.77A 1qfiB-4eogA:
undetectable		 1qfiB-4eogA:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_A_SAMA501_0
(BIOTIN SYNTHASE)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		5 / 12 THR A 166
GLY A 168
ILE A  90
LEU A 113
LEU A  37
 None
 1.15A 1r30A-4eogA:
undetectable		 1r30A-4eogA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_B_SAMB501_0
(BIOTIN SYNTHASE)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		5 / 12 THR A 166
GLY A 168
ILE A  90
LEU A 113
LEU A  37
 None
 1.15A 1r30B-4eogA:
undetectable		 1r30B-4eogA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF2_0
(7-AMINO-ACTINOMYCIN
D)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		3 / 3 THR A 176
PRO A 173
THR A 174
 None
 0.85A 1unjF-4eogA:
undetectable		 1unjF-4eogA:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF8_0
(7-AMINO-ACTINOMYCIN
D)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		3 / 3 THR A 174
THR A 176
PRO A 173
 None
 0.83A 1unjF-4eogA:
undetectable		 1unjF-4eogA:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		3 / 3 THR A 176
PRO A 173
THR A 174
 None
 0.82A 1unjL-4eogA:
undetectable		 1unjL-4eogA:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		3 / 3 THR A 174
THR A 176
PRO A 173
 None
 0.78A 1unjL-4eogA:
undetectable		 1unjL-4eogA:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		3 / 3 THR A 176
PRO A 173
THR A 174
 None
 0.85A 1unjR-4eogA:
undetectable		 1unjR-4eogA:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		3 / 3 THR A 174
THR A 176
PRO A 173
 None
 0.80A 1unjR-4eogA:
undetectable		 1unjR-4eogA:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_W_DVAW8_0
(7-AMINO-ACTINOMYCIN
D)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		3 / 3 THR A 174
THR A 176
PRO A 173
 None
 0.75A 1unjW-4eogA:
undetectable		 1unjW-4eogA:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		3 / 3 THR A 176
PRO A 173
THR A 174
 None
 0.80A 1unjX-4eogA:
undetectable		 1unjX-4eogA:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		3 / 3 THR A 174
THR A 176
PRO A 173
 None
 0.77A 1unjX-4eogA:
undetectable		 1unjX-4eogA:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		3 / 3 THR A 176
PRO A 173
THR A 174
 None
 0.78A 1unmE-4eogA:
undetectable		 1unmE-4eogA:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE8_0
(7-AMINOACTINOMYCIN D)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		3 / 3 THR A 174
THR A 176
PRO A 173
 None
 0.73A 1unmE-4eogA:
undetectable		 1unmE-4eogA:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		3 / 3 THR A 176
PRO A 173
THR A 174
 None
 0.83A 1unmF-4eogA:
undetectable		 1unmF-4eogA:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF8_0
(7-AMINOACTINOMYCIN D)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		3 / 3 THR A 174
THR A 176
PRO A 173
 None
 0.78A 1unmF-4eogA:
undetectable		 1unmF-4eogA:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UUJ_B_ACTB1077_0
(PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
ALPHA SUBUNIT)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		3 / 3 ARG A 178
TYR A 142
LYS A 305
 SO4  A 504 (-4.5A)
SO4  A 504 (-4.7A)
SO4  A 504 (-2.8A)
 0.86A 1uujB-4eogA:
undetectable		 1uujB-4eogA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_A_CAMA1416_0
(CYTOCHROME P450-CAM)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		4 / 8 THR A   8
LEU A   6
VAL A  38
VAL A  94
 None
 1.16A 1uyuA-4eogA:
undetectable		 1uyuA-4eogA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC8_0
(N8-ACTINOMYCIN D)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		3 / 3 THR A 174
THR A 176
PRO A 173
 None
 0.85A 209dC-4eogA:
undetectable		 209dC-4eogA:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FL5_F_RBFF204_1
(IMMUNOGLOBULIN IGG1
LAMBDA LIGHT CHAIN
IMMUNOGLOBULIN IGG1
HEAVY CHAIN)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		4 / 8 TYR A 162
ARG A   4
GLU A 160
VAL A 198
 None
 1.16A 2fl5E-4eogA:
undetectable
2fl5F-4eogA:
undetectable		 2fl5E-4eogA:
16.28
2fl5F-4eogA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		5 / 12 TYR A 459
PHE A 341
LEU A 351
ALA A 258
SER A 259
 None
 1.49A 3apvA-4eogA:
undetectable		 3apvA-4eogA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXT_A_SAMA397_0
(PROBABLE
N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE
TRM1)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		5 / 12 LEU A 410
ALA A 408
ILE A 402
SER A 403
ALA A 393
 None
 1.18A 3axtA-4eogA:
undetectable		 3axtA-4eogA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4W_A_MIGA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		5 / 12 ILE A 120
ILE A  48
TRP A  10
PHE A  14
HIS A  89
 None
 1.32A 3l4wA-4eogA:
undetectable		 3l4wA-4eogA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PO7_A_ZONA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		4 / 8 TYR A  75
LEU A 275
TYR A 144
PHE A 278
 None
 1.30A 3po7A-4eogA:
undetectable		 3po7A-4eogA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q1E_D_T44D328_1
(5-HYDROXYISOURATE
HYDROLASE)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		5 / 9 LEU A  37
LEU A   6
THR A   9
LEU A 165
LEU A 163
 None
 1.35A 3q1eB-4eogA:
undetectable
3q1eD-4eogA:
undetectable		 3q1eB-4eogA:
13.07
3q1eD-4eogA:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FWD_A_BO2A801_1
(TTC1975 PEPTIDASE)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		5 / 9 VAL A 430
VAL A 429
ILE A 434
GLY A 438
ALA A 469
 None
 1.14A 4fwdA-4eogA:
undetectable		 4fwdA-4eogA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4E_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		4 / 8 THR A   8
LEU A   6
VAL A  38
VAL A  94
 None
 1.17A 4l4eA-4eogA:
undetectable		 4l4eA-4eogA:
24.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		5 / 12 ILE A 434
LEU A 473
ILE A 347
PHE A 253
SER A 247
 None
 1.29A 5tiwB-4eogA:
undetectable		 5tiwB-4eogA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		4 / 5 ILE A 331
PHE A 457
ASN A 432
TYR A 441
 None
None
ZN  A 502 ( 4.2A)
None
 1.17A 6a93B-4eogA:
undetectable		 6a93B-4eogA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRX_A_H8GA1201_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 4eog PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		5 / 12 ALA A 435
PHE A 253
ASN A 251
VAL A 256
TYR A 459
 None
 1.32A 6drxA-4eogA:
undetectable		 6drxA-4eogA:
22.09